NO940610D0 - Oksazolidinedionderivater, deres fremstilling og anvendelse - Google Patents

Oksazolidinedionderivater, deres fremstilling og anvendelse

Info

Publication number
NO940610D0
NO940610D0 NO940610A NO940610A NO940610D0 NO 940610 D0 NO940610 D0 NO 940610D0 NO 940610 A NO940610 A NO 940610A NO 940610 A NO940610 A NO 940610A NO 940610 D0 NO940610 D0 NO 940610D0
Authority
NO
Norway
Prior art keywords
combine
substituted
alkyl group
hydrocarbon residue
preparation
Prior art date
Application number
NO940610A
Other languages
English (en)
Other versions
NO305079B1 (no
NO940610L (no
Inventor
Takashi Sohda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO940610D0 publication Critical patent/NO940610D0/no
Publication of NO940610L publication Critical patent/NO940610L/no
Publication of NO305079B1 publication Critical patent/NO305079B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
NO940610A 1993-02-26 1994-02-23 Oksazolidindion-derivater, legemidler inneholdende disse og deres anvendelse NO305079B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3823693 1993-02-26
JP19730493 1993-08-09

Publications (3)

Publication Number Publication Date
NO940610D0 true NO940610D0 (no) 1994-02-23
NO940610L NO940610L (no) 1994-08-29
NO305079B1 NO305079B1 (no) 1999-03-29

Family

ID=26377445

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940610A NO305079B1 (no) 1993-02-26 1994-02-23 Oksazolidindion-derivater, legemidler inneholdende disse og deres anvendelse

Country Status (18)

Country Link
US (4) US5665748A (no)
EP (1) EP0612743B1 (no)
JP (2) JP3328720B2 (no)
KR (1) KR940019699A (no)
CN (1) CN1098411A (no)
AT (1) ATE157975T1 (no)
AU (1) AU673034B2 (no)
CA (1) CA2116387C (no)
DE (1) DE69405425T2 (no)
DK (1) DK0612743T3 (no)
ES (1) ES2108375T3 (no)
FI (1) FI940904A (no)
GR (1) GR3025342T3 (no)
HU (1) HUT70159A (no)
NO (1) NO305079B1 (no)
PH (1) PH31468A (no)
RU (1) RU2126797C1 (no)
TW (1) TW268952B (no)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5468762A (en) * 1994-05-18 1995-11-21 American Home Products Corporation Azolidinediones as antihyperglycemic agents
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
CA2171702A1 (en) * 1995-03-14 1996-09-15 Takashi Sohda Benzofuran compounds and their use
JPH09136877A (ja) * 1995-06-16 1997-05-27 Takeda Chem Ind Ltd 複素環化合物、その製造法及び用途
PT891340E (pt) 1996-04-03 2003-03-31 Takeda Chemical Industries Ltd Derivados de oxazol sua preparacao e utilizacao
JPH09323930A (ja) * 1996-04-04 1997-12-16 Takeda Chem Ind Ltd 悪液質の予防・治療剤
US5889025A (en) * 1996-05-06 1999-03-30 Reddy's Research Foundation Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
FR2749583B1 (fr) 1996-06-07 1998-08-21 Lipha Nouveaux derives de thiazolidine -2,4- dione substitues, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
BR9711098B1 (pt) 1996-07-01 2011-10-04 compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos e seu uso no tratamento de diabetes e doenças relacionadas.
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
BR9711627A (pt) 1996-08-19 1999-08-24 Japan Tobacco Inc Derivados de cido propiÄnico e seu uso
US6011036A (en) * 1997-04-15 2000-01-04 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
US6011031A (en) * 1997-05-30 2000-01-04 Dr. Reddy's Research Foundation Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
EP1087963B1 (en) 1998-06-19 2004-08-25 Chiron Corporation Inhibitors of glycogen synthase kinase 3
CN1053186C (zh) * 1998-07-09 2000-06-07 华东理工大学 喹啉噁唑啉化合物
JP2000044551A (ja) * 1998-07-27 2000-02-15 Konica Corp 3−置換−3−オキソ−2−(2,4−オキサゾリジンジオン−3−イル)プロピオン酸アミド化合物の製造方法
WO2000018745A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Oxazolidine derivatives for the treatment and prevention of metabolic bone disorders
US6121300A (en) * 1998-11-10 2000-09-19 Wagle; Dilip R. Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
DE69929635T2 (de) * 1998-12-01 2006-09-21 Dr. Reddy's Research Foundation, Hyderabad Neue pharmazeutische zusammenstellung und deren herstellungsprozess
AU757729B2 (en) 1999-04-07 2003-03-06 Sankyo Company Limited Amine derivatives
ATE333448T1 (de) 1999-06-18 2006-08-15 Merck & Co Inc Arylthiazolidinedione und aryloxa zolidinedion- derivate
DE60032898T2 (de) 1999-06-18 2007-10-25 Merck & Co., Inc. Arylthiazolidindion- und aryloxazolidinderivate
GB9914977D0 (en) 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
JP4316787B2 (ja) * 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、
US7105551B2 (en) 2000-12-20 2006-09-12 Smithkline Beecham Corporation Thiazole derivatives for treating PPAR related disorders
WO2002076959A1 (fr) * 2001-03-23 2002-10-03 Takeda Chemical Industries, Ltd. Derive heterocyclique a cinq membres d'acide alcanoique
AU2003203170A1 (en) * 2002-01-17 2003-07-30 Takeda Chemical Industries, Ltd. Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof
TWI327462B (en) * 2002-01-18 2010-07-21 Sumitomo Chemical Co Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same
US7232828B2 (en) 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
US7521465B2 (en) * 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US6794401B2 (en) * 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
JP2006525329A (ja) 2003-04-30 2006-11-09 ジ インスチチュート フォー ファーマシューティカル ディスカバリー、エルエルシー 置換カルボン酸類
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
US20060100251A1 (en) * 2004-10-28 2006-05-11 The Institutes For Pharmaceutical Discovery, Llc Substituted phenylalkanoic acids
TW200932219A (en) * 2007-10-24 2009-08-01 Astellas Pharma Inc Oxadiazolidinedione compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US5232925A (en) * 1987-09-04 1993-08-03 Beecham Group P.L.C. Compounds
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
JP2991801B2 (ja) * 1990-04-27 1999-12-20 三共株式会社 ベンジリデンチアゾリジン化合物
US5037842A (en) * 1990-06-05 1991-08-06 Pfizer Inc. Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
ES2161692T3 (es) * 1991-04-11 2001-12-16 Upjohn Co Derivados de tiazolidindiona, produccion y uso de los mismos.
DK0597102T3 (da) * 1991-07-30 1999-08-09 Yamanouchi Pharma Co Ltd Nyt bisheterocyklisk derivat og salt heraf samt hypoglykæmisk sammensætning
JPH05202042A (ja) * 1992-01-24 1993-08-10 Sankyo Co Ltd 糖尿病性合併症治療剤
KR0146931B1 (ko) * 1992-04-30 1998-08-17 고바야시 유끼오 옥사졸리딘 유도체 및 그의 약학적으로 허용가능한 염
US5928152A (en) * 1994-08-05 1999-07-27 Acuson Corporation Method and apparatus for a baseband processor of a receive beamformer system

Also Published As

Publication number Publication date
US6552058B1 (en) 2003-04-22
EP0612743A1 (en) 1994-08-31
DK0612743T3 (da) 1998-04-20
US5665748A (en) 1997-09-09
TW268952B (no) 1996-01-21
HU9400578D0 (en) 1994-05-30
CA2116387A1 (en) 1994-08-27
DE69405425T2 (de) 1998-03-19
DE69405425D1 (de) 1997-10-16
US6147099A (en) 2000-11-14
NO305079B1 (no) 1999-03-29
AU5515894A (en) 1994-09-01
NO940610L (no) 1994-08-29
US5972970A (en) 1999-10-26
FI940904A0 (fi) 1994-02-25
JP3328720B2 (ja) 2002-09-30
EP0612743B1 (en) 1997-09-10
ES2108375T3 (es) 1997-12-16
JP2000191651A (ja) 2000-07-11
ATE157975T1 (de) 1997-09-15
GR3025342T3 (en) 1998-02-27
RU2126797C1 (ru) 1999-02-27
CA2116387C (en) 2003-12-23
FI940904A (fi) 1994-11-29
CN1098411A (zh) 1995-02-08
HUT70159A (en) 1995-09-28
PH31468A (en) 1998-11-03
AU673034B2 (en) 1996-10-24
KR940019699A (ko) 1994-09-14
JPH07165735A (ja) 1995-06-27

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN AUGUST 2002