RU2011146553A - Праймеры для диагностики дистрофии роговицы авеллино - Google Patents

Праймеры для диагностики дистрофии роговицы авеллино Download PDF

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RU2011146553A
RU2011146553A RU2011146553/10A RU2011146553A RU2011146553A RU 2011146553 A RU2011146553 A RU 2011146553A RU 2011146553/10 A RU2011146553/10 A RU 2011146553/10A RU 2011146553 A RU2011146553 A RU 2011146553A RU 2011146553 A RU2011146553 A RU 2011146553A
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seq
nos
real
time pcr
diagnosis
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RU2534817C2 (ru
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Чин ЛИ
Чон Кук ЮН
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Авеллино Ко., Лтд
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/113—Real time assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

1. Пара праймеров для ПЦР в режиме реального времени для диагностики дистрофии роговицы Авеллино, которая представлена нуклеотидными последовательностями, выбираемыми из группы, состоящей из последовательностей SEQ ID NOs: 1 и 2, SEQ ID NOs: 3 и 4, SEQ ID NOs: 5 и 6, SEQ ID NOs: 7 и 8, SEQ ID NOs: 9 и 10, SEQ ID NOs: 11 и 12, SEQ ID NOs: 13 и 14, SEQ ID NOs: 15 и 16, SEQ ID NOs: 17 и 18, SEQ ID NOs: 19 и 20, SEQ ID NOs: 21 и 22 и SEQ ID NOs: 23 и 24.2. Зонд для ПЦР в режиме реального времени для диагностики дистрофии роговицы Авеллино, который представлен нуклеотидной последовательностью, выбираемой из группы, состоящей из последовательностей от SEQ ID NO: 25 до SEQ ID NO: 42.3. Зонд для ПЦР в режиме реального времени для диагностики дистрофии роговицы Авеллино по п.2, где зонд для ПЦР в режиме реального времени является меченым VIC или FAM.

Claims (3)

1. Пара праймеров для ПЦР в режиме реального времени для диагностики дистрофии роговицы Авеллино, которая представлена нуклеотидными последовательностями, выбираемыми из группы, состоящей из последовательностей SEQ ID NOs: 1 и 2, SEQ ID NOs: 3 и 4, SEQ ID NOs: 5 и 6, SEQ ID NOs: 7 и 8, SEQ ID NOs: 9 и 10, SEQ ID NOs: 11 и 12, SEQ ID NOs: 13 и 14, SEQ ID NOs: 15 и 16, SEQ ID NOs: 17 и 18, SEQ ID NOs: 19 и 20, SEQ ID NOs: 21 и 22 и SEQ ID NOs: 23 и 24.
2. Зонд для ПЦР в режиме реального времени для диагностики дистрофии роговицы Авеллино, который представлен нуклеотидной последовательностью, выбираемой из группы, состоящей из последовательностей от SEQ ID NO: 25 до SEQ ID NO: 42.
3. Зонд для ПЦР в режиме реального времени для диагностики дистрофии роговицы Авеллино по п.2, где зонд для ПЦР в режиме реального времени является меченым VIC или FAM.
RU2011146553/10A 2009-04-17 2009-12-01 Праймеры для диагностики дистрофии роговицы авеллино RU2534817C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2009-0033528 2009-04-17
KR1020090033528A KR101251538B1 (ko) 2009-04-17 2009-04-17 아벨리노 각막이상증 진단용 프라이머
PCT/KR2009/007099 WO2010120027A1 (ko) 2009-04-17 2009-12-01 아벨리노 각막이상증 진단용 프라이머

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RU2011146553A true RU2011146553A (ru) 2013-05-27
RU2534817C2 RU2534817C2 (ru) 2014-12-10

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US (4) US20120077200A1 (ru)
EP (2) EP2420574B1 (ru)
JP (1) JP5738842B2 (ru)
KR (1) KR101251538B1 (ru)
CN (3) CN102459593B (ru)
AU (1) AU2009344501A1 (ru)
BR (1) BRPI0924016A2 (ru)
CA (1) CA2759222A1 (ru)
IL (1) IL215845A0 (ru)
RU (1) RU2534817C2 (ru)
SG (1) SG175732A1 (ru)
WO (1) WO2010120027A1 (ru)
ZA (1) ZA201107967B (ru)

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US20180274034A1 (en) 2018-09-27
CN110872613A (zh) 2020-03-10
EP2420574B1 (en) 2014-10-29
CN102459593A (zh) 2012-05-16
JP2012523831A (ja) 2012-10-11
KR101251538B1 (ko) 2013-04-08
EP2420574A4 (en) 2012-08-29
EP2420574A1 (en) 2012-02-22
US11268146B2 (en) 2022-03-08
EP2848689A1 (en) 2015-03-18
CN104774930A (zh) 2015-07-15
CA2759222A1 (en) 2010-10-21
US9938581B2 (en) 2018-04-10
US20120077200A1 (en) 2012-03-29
AU2009344501A1 (en) 2011-11-17
ZA201107967B (en) 2013-08-28
CN102459593B (zh) 2015-04-08
US20220205044A1 (en) 2022-06-30
JP5738842B2 (ja) 2015-06-24
RU2534817C2 (ru) 2014-12-10
WO2010120027A1 (ko) 2010-10-21
BRPI0924016A2 (pt) 2016-10-11
KR20100115030A (ko) 2010-10-27
US20150093751A1 (en) 2015-04-02
IL215845A0 (en) 2012-01-31
SG175732A1 (en) 2011-12-29

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