RU2010113986A - Применение пептида в качестве терапевтического средства - Google Patents
Применение пептида в качестве терапевтического средства Download PDFInfo
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- RU2010113986A RU2010113986A RU2010113986/15A RU2010113986A RU2010113986A RU 2010113986 A RU2010113986 A RU 2010113986A RU 2010113986/15 A RU2010113986/15 A RU 2010113986/15A RU 2010113986 A RU2010113986 A RU 2010113986A RU 2010113986 A RU2010113986 A RU 2010113986A
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- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract 11
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 11
- 239000000203 mixture Substances 0.000 claims abstract 8
- 208000023275 Autoimmune disease Diseases 0.000 claims abstract 5
- 208000035473 Communicable disease Diseases 0.000 claims abstract 5
- 206010016654 Fibrosis Diseases 0.000 claims abstract 5
- 208000019693 Lung disease Diseases 0.000 claims abstract 5
- 210000004204 blood vessel Anatomy 0.000 claims abstract 5
- 201000011510 cancer Diseases 0.000 claims abstract 5
- 201000010099 disease Diseases 0.000 claims abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 5
- 230000004761 fibrosis Effects 0.000 claims abstract 5
- 208000015181 infectious disease Diseases 0.000 claims abstract 5
- 208000027866 inflammatory disease Diseases 0.000 claims abstract 5
- 208000030159 metabolic disease Diseases 0.000 claims abstract 5
- 230000004770 neurodegeneration Effects 0.000 claims abstract 5
- 208000015122 neurodegenerative disease Diseases 0.000 claims abstract 5
- 210000004251 human milk Anatomy 0.000 claims abstract 4
- 235000020256 human milk Nutrition 0.000 claims abstract 4
- 239000007788 liquid Substances 0.000 claims abstract 4
- 230000002265 prevention Effects 0.000 claims abstract 3
- 239000000872 buffer Substances 0.000 claims abstract 2
- 239000007853 buffer solution Substances 0.000 claims abstract 2
- 239000002577 cryoprotective agent Substances 0.000 claims abstract 2
- 239000003085 diluting agent Substances 0.000 claims abstract 2
- 208000016097 disease of metabolism Diseases 0.000 claims abstract 2
- 239000003937 drug carrier Substances 0.000 claims abstract 2
- 238000001990 intravenous administration Methods 0.000 claims abstract 2
- -1 lyoprotector Substances 0.000 claims abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract 2
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Abstract
1. Применение пептида Ac-His-Trp-Ala-Val-Gly-His-Leu-NH2 или его деацетилированной формы для получения фармацевтической композиции для лечения и/или профилактики злокачественной опухоли, аутоиммунных заболеваний, фиброзов, воспалительных заболеваний, нейродегенеративных заболеваний, инфекционных заболеваний, заболеваний легких, заболеваний сердца и сосудов и болезней обмена веществ. ! 2. Применение пептида по п.1, где злокачественная опухоль, аутоиммунное заболевание, фиброз, воспалительное заболевание, нейродегенеративное заболевание, инфекционное заболевание, заболевание легких, заболевание сердца и сосудов или болезнь обмена веществ выбраны из инфекции HBV. ! 3. Применение пептида по п.1 или 2 для получения состава для перорального введения новорожденным, детям ясельного возраста и/или детям дошкольного возраста. !4. Применение пептида по п.1 или 2 для получения лиофилизированного состава или буферного жидкого состава. ! 5. Фармацевтическая композиция, содержащая пептид Ac-His-Trp-Ala-Val-Gly-His-Leu-NH2 или его деацетилированную форму совместно с по меньшей мере одним фармацевтически приемлемым носителем, криопротектором, лиопротектором, эксципиентом и/или разбавителем. ! 6. Фармацевтическая композиция по п.5 в форме лиофилизата или жидкого буферного раствора. ! 7. Фармацевтическая композиция по п.5 или 6, пригодная для внутривенного введения, перорального введения или для введения посредством ингаляции. ! 8. Фармацевтическая композиция по п.5 или 6 в форме состава искусственного материнского молока или заменителя материнского молока, пригодная для пероральной доставки новорожденным, детям ясельного возраста и/или детям дошкольного в
Claims (9)
1. Применение пептида Ac-His-Trp-Ala-Val-Gly-His-Leu-NH2 или его деацетилированной формы для получения фармацевтической композиции для лечения и/или профилактики злокачественной опухоли, аутоиммунных заболеваний, фиброзов, воспалительных заболеваний, нейродегенеративных заболеваний, инфекционных заболеваний, заболеваний легких, заболеваний сердца и сосудов и болезней обмена веществ.
2. Применение пептида по п.1, где злокачественная опухоль, аутоиммунное заболевание, фиброз, воспалительное заболевание, нейродегенеративное заболевание, инфекционное заболевание, заболевание легких, заболевание сердца и сосудов или болезнь обмена веществ выбраны из инфекции HBV.
3. Применение пептида по п.1 или 2 для получения состава для перорального введения новорожденным, детям ясельного возраста и/или детям дошкольного возраста.
4. Применение пептида по п.1 или 2 для получения лиофилизированного состава или буферного жидкого состава.
5. Фармацевтическая композиция, содержащая пептид Ac-His-Trp-Ala-Val-Gly-His-Leu-NH2 или его деацетилированную форму совместно с по меньшей мере одним фармацевтически приемлемым носителем, криопротектором, лиопротектором, эксципиентом и/или разбавителем.
6. Фармацевтическая композиция по п.5 в форме лиофилизата или жидкого буферного раствора.
7. Фармацевтическая композиция по п.5 или 6, пригодная для внутривенного введения, перорального введения или для введения посредством ингаляции.
8. Фармацевтическая композиция по п.5 или 6 в форме состава искусственного материнского молока или заменителя материнского молока, пригодная для пероральной доставки новорожденным, детям ясельного возраста и/или детям дошкольного возраста.
9. Фармацевтическая композиция по п.5 или 6, пригодная для лечения и/или профилактики злокачественной опухоли, аутоиммунного заболевания, фиброза, воспалительного заболевания, нейродегенеративного заболевания, инфекционного заболевания, заболевания легких, заболевания сердца и сосудов или болезней обмена веществ.
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EP07017766 | 2007-09-11 | ||
EP07017766.2 | 2007-09-11 |
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RU2010114015/15A RU2010114015A (ru) | 2007-09-11 | 2008-09-09 | Применение пептида в качестве терапевтического средства |
RU2010113967/15A RU2010113967A (ru) | 2007-09-11 | 2008-09-09 | Применение родственного стресскопину пептида в качестве терапевтического средства |
RU2010113976/15A RU2010113976A (ru) | 2007-09-11 | 2008-09-09 | Применение glp-1 в качестве терапевтического средства |
RU2010114020/15A RU2010114020A (ru) | 2007-09-11 | 2008-09-09 | Trap-14 в качестве терапевтического средства |
RU2010114036/15A RU2010114036A (ru) | 2007-09-11 | 2008-09-09 | ПРИМЕНЕНИЕ ПЕПТИДА His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe ИНДИВИДУАЛЬНО ИЛИ В СОЧЕТАНИИ С ПЕПТИДОМ Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH В КАЧЕСТВЕ ТЕРАПЕВТИЧЕСКОГО СРЕДСТВА |
RU2010114061/15A RU2010114061A (ru) | 2007-09-11 | 2008-09-09 | ПРИМЕНЕНИЕ ПЕПТИДА His-Ser-Leu-Gly-Lys-Trp-Leu-His-Pro-Asp-Lys-Phe ИНДИВИДУАЛЬНО ИЛИ В КОМБИНАЦИИ С ПЕПТИДОМ Gly-Arg-Gly-Asp-Asn-Pro-OH В КАЧЕСТВЕ ТЕРАПЕВТИЧЕСКОГО СРЕДСТВА |
RU2010113986/15A RU2010113986A (ru) | 2007-09-11 | 2008-09-09 | Применение пептида в качестве терапевтического средства |
RU2010113971/15A RU2010113971A (ru) | 2007-09-11 | 2008-09-09 | Применение пептида yy отдельно или в сочетании с глюкагоноподобным пептидом для применения в медицине |
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RU2010114015/15A RU2010114015A (ru) | 2007-09-11 | 2008-09-09 | Применение пептида в качестве терапевтического средства |
RU2010113967/15A RU2010113967A (ru) | 2007-09-11 | 2008-09-09 | Применение родственного стресскопину пептида в качестве терапевтического средства |
RU2010113976/15A RU2010113976A (ru) | 2007-09-11 | 2008-09-09 | Применение glp-1 в качестве терапевтического средства |
RU2010114020/15A RU2010114020A (ru) | 2007-09-11 | 2008-09-09 | Trap-14 в качестве терапевтического средства |
RU2010114036/15A RU2010114036A (ru) | 2007-09-11 | 2008-09-09 | ПРИМЕНЕНИЕ ПЕПТИДА His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe ИНДИВИДУАЛЬНО ИЛИ В СОЧЕТАНИИ С ПЕПТИДОМ Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH В КАЧЕСТВЕ ТЕРАПЕВТИЧЕСКОГО СРЕДСТВА |
RU2010114061/15A RU2010114061A (ru) | 2007-09-11 | 2008-09-09 | ПРИМЕНЕНИЕ ПЕПТИДА His-Ser-Leu-Gly-Lys-Trp-Leu-His-Pro-Asp-Lys-Phe ИНДИВИДУАЛЬНО ИЛИ В КОМБИНАЦИИ С ПЕПТИДОМ Gly-Arg-Gly-Asp-Asn-Pro-OH В КАЧЕСТВЕ ТЕРАПЕВТИЧЕСКОГО СРЕДСТВА |
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CA (8) | CA2699083A1 (ru) |
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