RU2010113984A - Применение врр-в в качестве терапевтического средства - Google Patents
Применение врр-в в качестве терапевтического средства Download PDFInfo
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- RU2010113984A RU2010113984A RU2010113984/10A RU2010113984A RU2010113984A RU 2010113984 A RU2010113984 A RU 2010113984A RU 2010113984/10 A RU2010113984/10 A RU 2010113984/10A RU 2010113984 A RU2010113984 A RU 2010113984A RU 2010113984 A RU2010113984 A RU 2010113984A
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Abstract
1. Применение пептида Pyr-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro-OH для получения фармацевтической композиции для лечения и/или профилактики злокачественной опухоли, аутоиммунных заболеваний, фиброзов, воспалительных заболеваний, нейродегенеративных заболеваний, инфекционных заболеваний, заболеваний легких, заболеваний сердца и сосудов и болезней обмена веществ. ! 2. Применение пептида по п.1, где злокачественная опухоль, аутоиммунное заболевание, фиброз, воспалительное заболевание, нейродегенеративное заболевание, инфекционное заболевание, заболевание легких, заболевание сердца и сосудов или болезнь обмена веществ выбраны из инфекции вирусом гепатита B, заболеваний, вызываемых инфекцией вирусом гепатита B, а именно острого гепатита, хронического гепатита, острой печеночной недостаточности, цирроза печени, злокачественной опухоли, ассоциированной с инфекцией вирусом гепатита B. ! 3. Применение пептида по п.1 или 2 для получения состава для перорального введения новорожденным, детям ясельного возраста и/или детям дошкольного возраста. ! 4. Применение пептида по п.1 или 2 для получения лиофилизированного состава или буферного жидкого состава. ! 5. Фармацевтическая композиция, содержащая пептид Pyr-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro-OH совместно с по меньшей мере одним фармацевтически приемлемым носителем, криопротектором, лиопротектором, эксципиентом и/или разбавителем. ! 6. Фармацевтическая композиция по п.5 в форме лиофилизата или жидкого буферного раствора. ! 7. Фармацевтическая композиция по п.5 или 6, пригодная для внутривенного введения, перорального введения или для введения посредством ингаляции. ! 8. Фармацевтическая композиция по п.5 и
Claims (9)
1. Применение пептида Pyr-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro-OH для получения фармацевтической композиции для лечения и/или профилактики злокачественной опухоли, аутоиммунных заболеваний, фиброзов, воспалительных заболеваний, нейродегенеративных заболеваний, инфекционных заболеваний, заболеваний легких, заболеваний сердца и сосудов и болезней обмена веществ.
2. Применение пептида по п.1, где злокачественная опухоль, аутоиммунное заболевание, фиброз, воспалительное заболевание, нейродегенеративное заболевание, инфекционное заболевание, заболевание легких, заболевание сердца и сосудов или болезнь обмена веществ выбраны из инфекции вирусом гепатита B, заболеваний, вызываемых инфекцией вирусом гепатита B, а именно острого гепатита, хронического гепатита, острой печеночной недостаточности, цирроза печени, злокачественной опухоли, ассоциированной с инфекцией вирусом гепатита B.
3. Применение пептида по п.1 или 2 для получения состава для перорального введения новорожденным, детям ясельного возраста и/или детям дошкольного возраста.
4. Применение пептида по п.1 или 2 для получения лиофилизированного состава или буферного жидкого состава.
5. Фармацевтическая композиция, содержащая пептид Pyr-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro-OH совместно с по меньшей мере одним фармацевтически приемлемым носителем, криопротектором, лиопротектором, эксципиентом и/или разбавителем.
6. Фармацевтическая композиция по п.5 в форме лиофилизата или жидкого буферного раствора.
7. Фармацевтическая композиция по п.5 или 6, пригодная для внутривенного введения, перорального введения или для введения посредством ингаляции.
8. Фармацевтическая композиция по п.5 или 6 в форме состава искусственного материнского молока или заменителя материнского молока, пригодная для пероральной доставки новорожденным, детям ясельного возраста и/или детям дошкольного возраста.
9. Фармацевтическая композиция по п.5 или 6, пригодная для лечения и/или профилактики злокачественной опухоли, аутоиммунного заболевания, фиброза, воспалительного заболевания, нейродегенеративного заболевания, инфекционного заболевания, заболевания легких, заболевания сердца и сосудов или болезней обмена веществ.
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| CA2535748A1 (en) * | 2002-08-15 | 2004-02-26 | Vasculostatin, Llc | Pthrp-derived modulators of smooth muscle proliferation |
| US20050101535A1 (en) * | 2003-05-06 | 2005-05-12 | Rosenstein David H. | Use of a synthetic alpha-melanocyte stimulating hormone agonist to decrease steroid induced weight gain |
| FR2860004A1 (fr) * | 2003-09-18 | 2005-03-25 | Roussy Inst Gustave | Nouveau vecteur adenoviral pour l'infection de cellules deficientes ou depourvues en recepteurs car |
| US20050130893A1 (en) * | 2003-09-30 | 2005-06-16 | Joan Smith-Sonneborn | Use of opioids in prevention of and recovery from a stress-induced crash in blood pressure |
| CA2562676A1 (en) * | 2004-04-23 | 2005-12-15 | Applied Research Systems Ars Holding N.V. | Use of gpcr54 ligands for the treatment of infertility |
| US20070185025A1 (en) * | 2005-09-11 | 2007-08-09 | The Trustees Of Columbia University In The City Of New York | Filoviral immunosuppressive peptides and uses thereof |
| WO2007084211A2 (en) * | 2005-11-11 | 2007-07-26 | The General Hospital Corporation | Use of gpr54 ligands for treatment of reproductive disorders, proliferative disorders, and for contraception |
-
2008
- 2008-09-09 AU AU2008297930A patent/AU2008297930A1/en not_active Abandoned
- 2008-09-09 WO PCT/EP2008/007717 patent/WO2009040023A2/en active Application Filing
- 2008-09-09 JP JP2010523363A patent/JP2010538990A/ja active Pending
- 2008-09-09 AU AU2008297896A patent/AU2008297896A1/en not_active Abandoned
- 2008-09-09 EP EP08802149A patent/EP2188016B1/en not_active Not-in-force
- 2008-09-09 WO PCT/EP2008/007972 patent/WO2009033788A2/en active Application Filing
- 2008-09-09 KR KR1020107005608A patent/KR20100057051A/ko not_active Application Discontinuation
- 2008-09-09 EP EP08802072A patent/EP2187909A1/en not_active Withdrawn
- 2008-09-09 US US12/677,317 patent/US20100204141A1/en not_active Abandoned
- 2008-09-09 WO PCT/EP2008/007970 patent/WO2009033786A2/en active Application Filing
- 2008-09-09 JP JP2010523349A patent/JP2010538978A/ja active Pending
- 2008-09-09 WO PCT/EP2008/007796 patent/WO2009033748A2/en active Application Filing
- 2008-09-09 US US12/677,293 patent/US8541364B2/en not_active Expired - Fee Related
- 2008-09-09 WO PCT/EP2008/007512 patent/WO2009039970A1/en active Application Filing
- 2008-09-09 CA CA2698789A patent/CA2698789A1/en not_active Abandoned
- 2008-09-09 RU RU2010113984/10A patent/RU2010113984A/ru not_active Application Discontinuation
- 2008-09-09 AU AU2008303932A patent/AU2008303932A1/en not_active Abandoned
- 2008-09-09 EP EP08801998A patent/EP2185240A2/en not_active Withdrawn
- 2008-09-09 RU RU2010114039/15A patent/RU2010114039A/ru not_active Application Discontinuation
- 2008-09-09 RU RU2010114010/15A patent/RU2010114010A/ru not_active Application Discontinuation
- 2008-09-09 JP JP2010523385A patent/JP5385280B2/ja not_active Expired - Fee Related
- 2008-09-09 KR KR1020107005589A patent/KR20100058548A/ko not_active Application Discontinuation
- 2008-09-09 CA CA2698745A patent/CA2698745A1/en not_active Abandoned
- 2008-09-09 WO PCT/EP2008/007598 patent/WO2009033722A2/en active Application Filing
- 2008-09-09 CA CA2699039A patent/CA2699039A1/en not_active Abandoned
- 2008-09-09 WO PCT/EP2008/007435 patent/WO2009033660A2/en active Application Filing
- 2008-09-09 WO PCT/EP2008/008026 patent/WO2009046860A2/en active Application Filing
- 2008-09-09 WO PCT/EP2008/007546 patent/WO2009039996A2/en active Application Filing
- 2008-09-09 US US12/676,926 patent/US20100204149A1/en not_active Abandoned
- 2008-09-09 KR KR1020107005625A patent/KR20100058555A/ko not_active Application Discontinuation
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