RU2008129731A - Новые пептиды-т-хелперные антигенные детерминанты (thd) - Google Patents
Новые пептиды-т-хелперные антигенные детерминанты (thd) Download PDFInfo
- Publication number
- RU2008129731A RU2008129731A RU2008129731/04A RU2008129731A RU2008129731A RU 2008129731 A RU2008129731 A RU 2008129731A RU 2008129731/04 A RU2008129731/04 A RU 2008129731/04A RU 2008129731 A RU2008129731 A RU 2008129731A RU 2008129731 A RU2008129731 A RU 2008129731A
- Authority
- RU
- Russia
- Prior art keywords
- hla
- seq
- chimeric peptide
- peptide according
- pharmaceutical composition
- Prior art date
Links
- 230000000890 antigenic effect Effects 0.000 title 1
- 108091006116 chimeric peptides Proteins 0.000 claims abstract 19
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 13
- 230000004913 activation Effects 0.000 claims abstract 7
- 108010058597 HLA-DR Antigens Proteins 0.000 claims abstract 6
- 102000006354 HLA-DR Antigens Human genes 0.000 claims abstract 6
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims abstract 5
- 210000002443 helper t lymphocyte Anatomy 0.000 claims abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract 4
- 231100000433 cytotoxic Toxicity 0.000 claims abstract 3
- 230000001472 cytotoxic effect Effects 0.000 claims abstract 3
- 108010093013 HLA-DR1 Antigen Proteins 0.000 claims abstract 2
- 108010051539 HLA-DR2 Antigen Proteins 0.000 claims abstract 2
- 108010064885 HLA-DR3 Antigen Proteins 0.000 claims abstract 2
- 108010046732 HLA-DR4 Antigen Proteins 0.000 claims abstract 2
- 108010001041 HLA-DR7 Antigen Proteins 0.000 claims abstract 2
- 108010086066 HLA-DR8 antigen Proteins 0.000 claims abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract 2
- 150000001413 amino acids Chemical class 0.000 claims abstract 2
- 230000002163 immunogen Effects 0.000 claims abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract 2
- 230000001939 inductive effect Effects 0.000 claims 3
- 230000004936 stimulating effect Effects 0.000 claims 3
- 230000028996 humoral immune response Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ESP200503169 | 2005-12-23 | ||
| ES200503169A ES2310072B1 (es) | 2005-12-23 | 2005-12-23 | Nuevos peptidos determinantes antigenicos t colaboradores (/dth). |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008129731A true RU2008129731A (ru) | 2010-01-27 |
Family
ID=38217710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008129731/04A RU2008129731A (ru) | 2005-12-23 | 2006-12-19 | Новые пептиды-т-хелперные антигенные детерминанты (thd) |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090220533A1 (enExample) |
| EP (1) | EP1978026B1 (enExample) |
| JP (1) | JP2009520772A (enExample) |
| CN (1) | CN101374857A (enExample) |
| AT (1) | ATE502047T1 (enExample) |
| AU (1) | AU2006329789A1 (enExample) |
| BR (1) | BRPI0620243A2 (enExample) |
| CA (1) | CA2634840A1 (enExample) |
| DE (1) | DE602006020781D1 (enExample) |
| ES (1) | ES2310072B1 (enExample) |
| RU (1) | RU2008129731A (enExample) |
| WO (1) | WO2007074188A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375919B (zh) | 2009-03-27 | 2022-07-29 | 台湾地区“中央研究院” | 抗病毒免疫的方法和组合物 |
| TWI537385B (zh) | 2010-11-04 | 2016-06-11 | 中央研究院 | 產生具簡單醣基化之表面蛋白質之病毒顆粒的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0735893B1 (en) * | 1993-09-14 | 2008-11-26 | Pharmexa Inc. | Pan dr-binding peptides for enhancement of the immune response |
| EP0876398B1 (en) | 1996-01-24 | 2002-07-17 | Epimmune, Inc. | Induction of immune response against desired determinants |
| US6413517B1 (en) * | 1997-01-23 | 2002-07-02 | Epimmune, Inc. | Identification of broadly reactive DR restricted epitopes |
| CA2332786A1 (en) * | 1998-05-29 | 1999-12-02 | Epimmune Inc. | Identification of broadly reactive dr restricted epitopes |
| FR2824326B1 (fr) * | 2001-05-04 | 2004-03-19 | Commissariat Energie Atomique | Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications |
| US20040236514A1 (en) * | 2001-12-13 | 2004-11-25 | Lee Stephen C. | Controlling distribution of epitopes in polypeptide sequences |
-
2005
- 2005-12-23 ES ES200503169A patent/ES2310072B1/es not_active Expired - Fee Related
-
2006
- 2006-12-19 AU AU2006329789A patent/AU2006329789A1/en not_active Abandoned
- 2006-12-19 RU RU2008129731/04A patent/RU2008129731A/ru not_active Application Discontinuation
- 2006-12-19 AT AT06841747T patent/ATE502047T1/de not_active IP Right Cessation
- 2006-12-19 US US12/086,972 patent/US20090220533A1/en not_active Abandoned
- 2006-12-19 CA CA002634840A patent/CA2634840A1/en not_active Abandoned
- 2006-12-19 DE DE602006020781T patent/DE602006020781D1/de active Active
- 2006-12-19 JP JP2008546494A patent/JP2009520772A/ja not_active Withdrawn
- 2006-12-19 CN CNA2006800486390A patent/CN101374857A/zh active Pending
- 2006-12-19 BR BRPI0620243-8A patent/BRPI0620243A2/pt not_active IP Right Cessation
- 2006-12-19 EP EP06841747A patent/EP1978026B1/en active Active
- 2006-12-19 WO PCT/ES2006/000695 patent/WO2007074188A1/es not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE502047T1 (de) | 2011-04-15 |
| US20090220533A1 (en) | 2009-09-03 |
| EP1978026B1 (en) | 2011-03-16 |
| CA2634840A1 (en) | 2007-07-05 |
| JP2009520772A (ja) | 2009-05-28 |
| WO2007074188A1 (es) | 2007-07-05 |
| EP1978026A4 (en) | 2010-03-10 |
| EP1978026A1 (en) | 2008-10-08 |
| CN101374857A (zh) | 2009-02-25 |
| DE602006020781D1 (en) | 2011-04-28 |
| AU2006329789A1 (en) | 2007-07-05 |
| ES2310072B1 (es) | 2009-11-16 |
| ES2310072A1 (es) | 2008-12-16 |
| BRPI0620243A2 (pt) | 2011-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20110623 |