RU2000133310A - Генетический способ получения рибофлавина - Google Patents

Генетический способ получения рибофлавина Download PDF

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Publication number
RU2000133310A
RU2000133310A RU2000133310/13A RU2000133310A RU2000133310A RU 2000133310 A RU2000133310 A RU 2000133310A RU 2000133310/13 A RU2000133310/13 A RU 2000133310/13A RU 2000133310 A RU2000133310 A RU 2000133310A RU 2000133310 A RU2000133310 A RU 2000133310A
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RU
Russia
Prior art keywords
synthase
riboflavin
seq
genes
organism
Prior art date
Application number
RU2000133310/13A
Other languages
English (en)
Russian (ru)
Inventor
Хеннинг АЛЬТХЕФЕР (DE)
Хеннинг АЛЬТХЕФЕР
Харальд ЗОЙЛЬБЕРГЕР (DE)
Харальд ЗОЙЛЬБЕРГЕР
Оскар ЦЕЛЬДЕР (DE)
Оскар Цельдер
ДОВАЛЬ Хосе Луис РЕВУЭЛЬТА (ES)
ДОВАЛЬ Хосе Луис РЕВУЭЛЬТА
Original Assignee
БАСФ Акциенгезельшафт (DE)
Басф Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by БАСФ Акциенгезельшафт (DE), Басф Акциенгезельшафт filed Critical БАСФ Акциенгезельшафт (DE)
Publication of RU2000133310A publication Critical patent/RU2000133310A/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
RU2000133310/13A 1998-05-28 1999-05-10 Генетический способ получения рибофлавина RU2000133310A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823834A DE19823834A1 (de) 1998-05-28 1998-05-28 Genetisches Verfahren zur Herstellung von Riboflavin
DE19823834.7 1998-05-28

Publications (1)

Publication Number Publication Date
RU2000133310A true RU2000133310A (ru) 2002-12-27

Family

ID=7869161

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000133310/13A RU2000133310A (ru) 1998-05-28 1999-05-10 Генетический способ получения рибофлавина

Country Status (9)

Country Link
EP (1) EP1082438A2 (ko)
JP (1) JP2002516108A (ko)
KR (1) KR20010043867A (ko)
CN (1) CN1303434A (ko)
AU (1) AU4140999A (ko)
DE (1) DE19823834A1 (ko)
ID (1) ID27073A (ko)
RU (1) RU2000133310A (ko)
WO (1) WO1999061623A2 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01012842A (es) 1999-06-25 2002-07-09 Basf Ag Genes de corynebacterium glutamicum que codifican proteinas involucradas en el metabolismo del carbono y la produccion de energia.
CA2377378A1 (en) 1999-07-01 2001-01-11 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding phosphoenolpyruvate:sugar phosphotransferase system proteins
DE1246922T1 (de) 1999-07-01 2003-03-20 Basf Ag Für proteine des phosphoenolpyruvat:zucker phosphotransferase systems kodierende gene aus corynebacterium glutamicum
US7009045B2 (en) 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
AU2001273435A1 (en) * 2000-07-14 2002-01-30 Charles Abbas Transformation systems for flavinogenic yeast
DE10046870A1 (de) 2000-09-20 2002-03-28 Basf Ag Verfahren zur Veränderung des Genoms von Corynebakterien
EP1383903B1 (en) 2001-04-04 2008-09-24 Genencor International, Inc. Methods for the production of ascorbic acid intermediates in host cells
ATE421577T1 (de) 2001-04-04 2009-02-15 Genencor Int Entkoppelte anabole und katabole stoffwechselwege in wirtszellen
CA2454696A1 (en) * 2001-07-27 2003-02-13 Basf Aktiengesellschaft Novel genetic products of ashbya gossypii, associated with the mechanisms of signal transduction and especially with the improvement of vitamin b2 production
KR20040027959A (ko) * 2001-08-23 2004-04-01 바스프 악티엔게젤샤프트 아쉬비아 고쉬피로부터의 신규 대사-관련 유전자 산물
DE10159396A1 (de) * 2001-12-04 2003-06-12 Basf Ag Genetische Stammoptimierung zur verbesserten Herstellung von Riboflavin
DE10209363A1 (de) * 2002-03-02 2003-09-11 Basf Ag Verfahren zur Herstellung von Riboflavin
JP5565992B2 (ja) * 2005-09-28 2014-08-06 興人ライフサイエンス株式会社 酵母キャンディダ・ユティリスの形質転換法
JP5498651B2 (ja) * 2006-07-28 2014-05-21 花王株式会社 ジピコリン酸又はその塩の製造方法
CN104531745B (zh) * 2014-12-09 2018-05-04 江南大学 一种新型抗性质粒的构建及其在核黄素生产菌中的运用
CN113755551A (zh) * 2021-09-30 2021-12-07 天津科技大学 一种提高核黄素产量的发酵方法
CN114317557B (zh) * 2022-01-06 2023-07-07 河南农业大学 玉米ZmRIBA1基因在高赖氨酸玉米育种中的应用
CN116463305B (zh) * 2023-06-15 2023-10-17 北京易醒生物科技有限公司 一种提高用于乙醇氧化的醇氧化酶表达量的方法、优化的核黄素生物合成基因

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1066486C (zh) * 1989-06-22 2001-05-30 霍夫曼-拉罗奇有限公司 高产核黄素的细菌菌株
CA2111709A1 (en) * 1991-08-22 1993-03-04 Sabine Steiner The specific genetic modification of ashbya gossypii
DK0569806T3 (da) * 1992-05-11 2001-12-31 Basf Ag DNA-forbindelser og rekombinante DNA-ekspressionsvektorer, der koder for riboflavinsyntetaseaktivitet af S. cerevisiae
DE4420785A1 (de) * 1994-03-25 1995-10-05 Basf Ag Riboflavin-Biosynthese in Pilzen
DK0839211T3 (da) * 1995-07-13 2001-09-03 Basf Ag Fremgangsmåde til fremstilling af riboflavin ved hjælp af mikroorganismer med ændret isocitratlyaseaktivitet
JPH1084978A (ja) * 1996-07-24 1998-04-07 F Hoffmann La Roche Ag 改良されたリボフラビン生産

Also Published As

Publication number Publication date
WO1999061623A3 (de) 2000-01-27
KR20010043867A (ko) 2001-05-25
AU4140999A (en) 1999-12-13
EP1082438A2 (de) 2001-03-14
DE19823834A1 (de) 1999-12-02
WO1999061623A2 (de) 1999-12-02
ID27073A (id) 2001-02-22
CN1303434A (zh) 2001-07-11
JP2002516108A (ja) 2002-06-04

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Effective date: 20060215