RS56097B1 - (1r,4r)-6'-fluoro-(n-metil- ili n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro-[cikloheksan-1,1'-pirano[3,4,b]indol]-4-amin za lečenje fibromijalgije i sindroma hroničnog umora - Google Patents

(1r,4r)-6'-fluoro-(n-metil- ili n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro-[cikloheksan-1,1'-pirano[3,4,b]indol]-4-amin za lečenje fibromijalgije i sindroma hroničnog umora

Info

Publication number
RS56097B1
RS56097B1 RS20170602A RSP20170602A RS56097B1 RS 56097 B1 RS56097 B1 RS 56097B1 RS 20170602 A RS20170602 A RS 20170602A RS P20170602 A RSP20170602 A RS P20170602A RS 56097 B1 RS56097 B1 RS 56097B1
Authority
RS
Serbia
Prior art keywords
fibromyalgia
dosage form
pharmaceutical dosage
treatment
fluoro
Prior art date
Application number
RS20170602A
Other languages
English (en)
Serbian (sr)
Inventor
Stefanie Frosch
Klaus Linz
Petra Bloms-Funke
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of RS56097B1 publication Critical patent/RS56097B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
RS20170602A 2012-02-03 2013-02-01 (1r,4r)-6'-fluoro-(n-metil- ili n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro-[cikloheksan-1,1'-pirano[3,4,b]indol]-4-amin za lečenje fibromijalgije i sindroma hroničnog umora RS56097B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12000743 2012-02-03
PCT/EP2013/051979 WO2013113857A1 (en) 2012-02-03 2013-02-01 (1r,4r)-6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro-[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for treating fibromyalgia and chronic fatigue syndrome
EP13701807.3A EP2809320B1 (en) 2012-02-03 2013-02-01 (1r,4r)-6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro-[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for treating fibromyalgia and chronic fatigue syndrome

Publications (1)

Publication Number Publication Date
RS56097B1 true RS56097B1 (sr) 2017-10-31

Family

ID=47628188

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20170602A RS56097B1 (sr) 2012-02-03 2013-02-01 (1r,4r)-6'-fluoro-(n-metil- ili n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro-[cikloheksan-1,1'-pirano[3,4,b]indol]-4-amin za lečenje fibromijalgije i sindroma hroničnog umora

Country Status (23)

Country Link
US (1) US20130202701A1 (enExample)
EP (1) EP2809320B1 (enExample)
JP (1) JP6126134B2 (enExample)
KR (1) KR102061482B1 (enExample)
CN (1) CN104168897B (enExample)
AU (1) AU2013214223B2 (enExample)
BR (1) BR112014019136A8 (enExample)
CA (1) CA2863572C (enExample)
CY (1) CY1118799T1 (enExample)
DK (1) DK2809320T3 (enExample)
EA (1) EA025500B1 (enExample)
ES (1) ES2629211T3 (enExample)
HR (1) HRP20170581T1 (enExample)
IL (1) IL233871B (enExample)
LT (1) LT2809320T (enExample)
MX (1) MX353740B (enExample)
NZ (1) NZ629800A (enExample)
PL (1) PL2809320T3 (enExample)
PT (1) PT2809320T (enExample)
RS (1) RS56097B1 (enExample)
SI (1) SI2809320T1 (enExample)
WO (1) WO2013113857A1 (enExample)
ZA (1) ZA201406447B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10022353B2 (en) 2015-01-23 2018-07-17 Grünenthal GmbH Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900420A (en) * 1997-06-19 1999-05-04 Cole; William L. Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE10360792A1 (de) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
BRPI0509377A (pt) * 2004-03-29 2007-09-11 Pfizer compostos de ácido alfa arila ou heteroaril metil beta piperidino propanóico como antagonistas do receptor orl1
MX2008015048A (es) * 2006-05-31 2008-12-10 Sepracor Inc Tratamiento contra trastornos de dolor con trans 4-(3,4-diclorofenil)-1,2,3,4-tetrahidro-1-naftalenamina y su formamida.
DE102006046745A1 (de) * 2006-09-29 2008-04-03 Grünenthal GmbH Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz

Also Published As

Publication number Publication date
HK1199218A1 (en) 2015-06-26
AU2013214223B2 (en) 2017-03-23
US20130202701A1 (en) 2013-08-08
CN104168897A (zh) 2014-11-26
CA2863572C (en) 2019-08-27
EA201400857A1 (ru) 2015-01-30
EA025500B1 (ru) 2016-12-30
ES2629211T3 (es) 2017-08-07
JP6126134B2 (ja) 2017-05-10
CA2863572A1 (en) 2013-08-08
KR102061482B1 (ko) 2020-01-03
KR20140130695A (ko) 2014-11-11
NZ629800A (en) 2016-06-24
ZA201406447B (en) 2016-02-24
EP2809320A1 (en) 2014-12-10
IL233871B (en) 2018-06-28
PT2809320T (pt) 2017-06-30
SI2809320T1 (sl) 2017-07-31
WO2013113857A1 (en) 2013-08-08
BR112014019136A2 (enExample) 2017-06-20
IL233871A0 (en) 2014-09-30
MX353740B (es) 2018-01-26
PL2809320T3 (pl) 2017-09-29
DK2809320T3 (en) 2017-05-15
MX2014008865A (es) 2014-08-27
BR112014019136A8 (pt) 2017-07-11
EP2809320B1 (en) 2017-03-22
CY1118799T1 (el) 2018-01-10
CN104168897B (zh) 2016-09-28
AU2013214223A1 (en) 2014-09-18
HRP20170581T1 (hr) 2017-06-16
JP2015505553A (ja) 2015-02-23
LT2809320T (lt) 2017-05-25

Similar Documents

Publication Publication Date Title
US20090143344A1 (en) Methods for treating or preventing symptoms of hormonal variations
JP2019089812A (ja) メラトニンアゴニスト治療
AU736005B2 (en) Method for the treatment of neurological or neuropsychiatric disorders
CN107149601A (zh) 青蒿素类化合物在制备治疗神经病理性疼痛和/或并发症的药物中的应用
RS56097B1 (sr) (1r,4r)-6'-fluoro-(n-metil- ili n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro-[cikloheksan-1,1'-pirano[3,4,b]indol]-4-amin za lečenje fibromijalgije i sindroma hroničnog umora
US20030073733A1 (en) Pharmaceutically active compounds and methods of use
Sicuteri et al. Fenfluramine headache
HK1199218B (en) (1r,4r)-6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro-[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for treating fibromyalgia and chronic fatigue syndrome
US12502371B2 (en) Drug for treating and preventing dementia
TWI881778B (zh) 洋薊素用於治療及/或預防癲癇及降低抗癲癇藥物的副作用之用途
JP4615849B2 (ja) プロパフェノン含有神経因性疼痛の鎮痛剤
EP1997486B1 (en) Therapeutic agent for functional brain disease
TWI313607B (enExample)
WO2017113775A1 (zh) 甘油三酯类化合物在制备治疗神经退行性疾病药物中的应用
US20220362202A1 (en) Drug For Treating And Preventing Dementia
Kamath Study of Anticonvulsant Effect of Simvastatin in Maximal Electroshock and Pentylenetetrazole Induced Seizure Model in Albino Mice
JP2000505057A (ja) 膜発現の阻害を目的とするギンゴリド
US20170049737A1 (en) (2r)-2-propyloctanoic acid for functional brain disease
CN107007575A (zh) 治疗颅脑损伤所致精神障碍的药物组合物及应用
EA042299B1 (ru) Фармацевтические композиции и их применения
CN106924224A (zh) 一种治疗颅脑损伤所致精神障碍的药物组合物及其应用
CN107007607A (zh) 一种治疗颅脑损伤所致精神障碍的药物组合物及应用