SI2809320T1 - (1r,4r)-6'-fluoro-(N-metil- ali N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H -spiro(cikloheksan-1,1'-pirano(3,4,b)indol)-4-amin za zdravljenje fibromialgije in sindroma kronične utrujenosti - Google Patents
(1r,4r)-6'-fluoro-(N-metil- ali N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H -spiro(cikloheksan-1,1'-pirano(3,4,b)indol)-4-amin za zdravljenje fibromialgije in sindroma kronične utrujenostiInfo
- Publication number
- SI2809320T1 SI2809320T1 SI201330672A SI201330672A SI2809320T1 SI 2809320 T1 SI2809320 T1 SI 2809320T1 SI 201330672 A SI201330672 A SI 201330672A SI 201330672 A SI201330672 A SI 201330672A SI 2809320 T1 SI2809320 T1 SI 2809320T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pyrano
- indol
- spiro
- dihydro
- cyclohexane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12000743 | 2012-02-03 | ||
| PCT/EP2013/051979 WO2013113857A1 (en) | 2012-02-03 | 2013-02-01 | (1r,4r)-6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro-[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for treating fibromyalgia and chronic fatigue syndrome |
| EP13701807.3A EP2809320B1 (en) | 2012-02-03 | 2013-02-01 | (1r,4r)-6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro-[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for treating fibromyalgia and chronic fatigue syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2809320T1 true SI2809320T1 (sl) | 2017-07-31 |
Family
ID=47628188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201330672A SI2809320T1 (sl) | 2012-02-03 | 2013-02-01 | (1r,4r)-6'-fluoro-(N-metil- ali N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H -spiro(cikloheksan-1,1'-pirano(3,4,b)indol)-4-amin za zdravljenje fibromialgije in sindroma kronične utrujenosti |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20130202701A1 (sl) |
| EP (1) | EP2809320B1 (sl) |
| JP (1) | JP6126134B2 (sl) |
| KR (1) | KR102061482B1 (sl) |
| CN (1) | CN104168897B (sl) |
| AU (1) | AU2013214223B2 (sl) |
| BR (1) | BR112014019136A8 (sl) |
| CA (1) | CA2863572C (sl) |
| CY (1) | CY1118799T1 (sl) |
| DK (1) | DK2809320T3 (sl) |
| EA (1) | EA025500B1 (sl) |
| ES (1) | ES2629211T3 (sl) |
| HK (1) | HK1199218A1 (sl) |
| HR (1) | HRP20170581T1 (sl) |
| IL (1) | IL233871B (sl) |
| LT (1) | LT2809320T (sl) |
| MX (1) | MX353740B (sl) |
| NZ (1) | NZ629800A (sl) |
| PL (1) | PL2809320T3 (sl) |
| PT (1) | PT2809320T (sl) |
| RS (1) | RS56097B1 (sl) |
| SI (1) | SI2809320T1 (sl) |
| WO (1) | WO2013113857A1 (sl) |
| ZA (1) | ZA201406447B (sl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2974578C (en) | 2015-01-23 | 2020-11-17 | Grunenthal Gmbh | Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
| DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10360792A1 (de) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| MXPA06011265A (es) * | 2004-03-29 | 2006-12-15 | Pfizer | Compuestos propanamida alfa aril o heteroaril metil beta piperidino como antagonistas del receptor orl1. |
| CN101484210A (zh) * | 2006-05-31 | 2009-07-15 | 塞普拉科公司 | 用反-4-(3,4-二氯苯基)-1,2,3,4-四氢-1-萘胺及其甲酰胺治疗疼痛病 |
| DE102006046745A1 (de) | 2006-09-29 | 2008-04-03 | Grünenthal GmbH | Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz |
-
2013
- 2013-02-01 CA CA2863572A patent/CA2863572C/en not_active Expired - Fee Related
- 2013-02-01 KR KR1020147024696A patent/KR102061482B1/ko active IP Right Grant
- 2013-02-01 SI SI201330672A patent/SI2809320T1/sl unknown
- 2013-02-01 DK DK13701807.3T patent/DK2809320T3/en active
- 2013-02-01 EP EP13701807.3A patent/EP2809320B1/en active Active
- 2013-02-01 WO PCT/EP2013/051979 patent/WO2013113857A1/en active Application Filing
- 2013-02-01 PT PT137018073T patent/PT2809320T/pt unknown
- 2013-02-01 AU AU2013214223A patent/AU2013214223B2/en not_active Ceased
- 2013-02-01 MX MX2014008865A patent/MX353740B/es active IP Right Grant
- 2013-02-01 PL PL13701807T patent/PL2809320T3/pl unknown
- 2013-02-01 EA EA201400857A patent/EA025500B1/ru not_active IP Right Cessation
- 2013-02-01 RS RS20170602A patent/RS56097B1/sr unknown
- 2013-02-01 JP JP2014555212A patent/JP6126134B2/ja active Active
- 2013-02-01 NZ NZ629800A patent/NZ629800A/en not_active IP Right Cessation
- 2013-02-01 BR BR112014019136A patent/BR112014019136A8/pt not_active Application Discontinuation
- 2013-02-01 LT LTEP13701807.3T patent/LT2809320T/lt unknown
- 2013-02-01 ES ES13701807.3T patent/ES2629211T3/es active Active
- 2013-02-01 US US13/757,223 patent/US20130202701A1/en not_active Abandoned
- 2013-02-01 CN CN201380007809.0A patent/CN104168897B/zh not_active Expired - Fee Related
-
2014
- 2014-07-30 IL IL233871A patent/IL233871B/en active IP Right Grant
- 2014-09-02 ZA ZA2014/06447A patent/ZA201406447B/en unknown
- 2014-12-23 HK HK14112866.0A patent/HK1199218A1/xx not_active IP Right Cessation
-
2017
- 2017-04-03 CY CY20171100395T patent/CY1118799T1/el unknown
- 2017-04-11 HR HRP20170581TT patent/HRP20170581T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014019136A2 (sl) | 2017-06-20 |
| ES2629211T3 (es) | 2017-08-07 |
| HK1199218A1 (en) | 2015-06-26 |
| CY1118799T1 (el) | 2018-01-10 |
| JP6126134B2 (ja) | 2017-05-10 |
| IL233871B (en) | 2018-06-28 |
| CN104168897B (zh) | 2016-09-28 |
| EA025500B1 (ru) | 2016-12-30 |
| AU2013214223B2 (en) | 2017-03-23 |
| JP2015505553A (ja) | 2015-02-23 |
| IL233871A0 (en) | 2014-09-30 |
| US20130202701A1 (en) | 2013-08-08 |
| CN104168897A (zh) | 2014-11-26 |
| KR20140130695A (ko) | 2014-11-11 |
| ZA201406447B (en) | 2016-02-24 |
| RS56097B1 (sr) | 2017-10-31 |
| EP2809320B1 (en) | 2017-03-22 |
| MX353740B (es) | 2018-01-26 |
| LT2809320T (lt) | 2017-05-25 |
| EP2809320A1 (en) | 2014-12-10 |
| MX2014008865A (es) | 2014-08-27 |
| CA2863572A1 (en) | 2013-08-08 |
| KR102061482B1 (ko) | 2020-01-03 |
| WO2013113857A1 (en) | 2013-08-08 |
| AU2013214223A1 (en) | 2014-09-18 |
| HRP20170581T1 (hr) | 2017-06-16 |
| PL2809320T3 (pl) | 2017-09-29 |
| DK2809320T3 (en) | 2017-05-15 |
| CA2863572C (en) | 2019-08-27 |
| BR112014019136A8 (pt) | 2017-07-11 |
| PT2809320T (pt) | 2017-06-30 |
| NZ629800A (en) | 2016-06-24 |
| EA201400857A1 (ru) | 2015-01-30 |
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| GB2492154B (en) | Devices and methods for emanating liquids | |
| GB2492150B (en) | Devices and methods for emanating liquids | |
| ZA201400104B (en) | Devices and methods for emanating liquids | |
| HK1204940A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1- pyrano[3,4,b]indol]-4-amine and paracetamol or propacetamol (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- | |
| HK1204944A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1-pyrano [3,4,b]indol]-4-amine and antidepressants (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- | |
| SI2797923T1 (sl) | Trdne oblike hidroklorida (1r,4r)-6'-fluoro-N,N-dimetil-4-fenil-4',9'-dihidro-3'H-spiro (cikloheksan-1,1'-pirano(3,4,b)indol)-4-amina | |
| HK1204939A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1-pyrano [3,4,b]indol]-4-amine and an oxicam (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- | |
| AU2012904982A0 (en) | Device for treating respiratory disorders |