|
US6541224B2
(en)
|
1996-03-14 |
2003-04-01 |
Human Genome Sciences, Inc. |
Tumor necrosis factor delta polypeptides
|
|
US7217788B2
(en)
|
1996-03-14 |
2007-05-15 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta polypeptides
|
|
US8212004B2
(en)
|
1999-03-02 |
2012-07-03 |
Human Genome Sciences, Inc. |
Neutrokine-alpha fusion proteins
|
|
US6812327B1
(en)
|
1996-10-25 |
2004-11-02 |
Human Genome Sciences, Inc. |
Neutrokine-alpha polypeptides
|
|
ES2329851T3
(es)
|
1998-06-01 |
2009-12-01 |
Agensys, Inc. |
Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos.
|
|
GB9828628D0
(en)
|
1998-12-23 |
1999-02-17 |
Glaxo Group Ltd |
Novel ligand
|
|
US7833529B1
(en)
|
1999-01-07 |
2010-11-16 |
Zymogenetics, Inc. |
Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
|
|
US20030095967A1
(en)
*
|
1999-01-25 |
2003-05-22 |
Mackay Fabienne |
BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
|
|
US20050100548A1
(en)
*
|
2001-07-24 |
2005-05-12 |
Biogen Idec Ma Inc. |
BAFF, inhibitors thereof and their use in the modulation of B-cell response
|
|
EP1210425B2
(en)
|
1999-08-17 |
2015-06-17 |
Biogen MA Inc. |
Baff receptor (bcma), an immunoregulatory agent
|
|
EP1666052B1
(en)
*
|
2000-02-16 |
2011-06-08 |
Genentech, Inc. |
Anti-APRIL monoclonal antibody and its use for the treatment of an immune related disease or cancer
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US7371388B1
(en)
|
2000-05-04 |
2008-05-13 |
Human Genome Sciences, Inc. |
Treatment of Sjogren's syndrome by administration of TR18 polypeptides
|
|
US6774106B2
(en)
|
2000-05-12 |
2004-08-10 |
Amgen Inc. |
Methods and compositions of matter concerning APRIL/G70, BCMA, BLYS/AGP-3 and TACI
|
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
WO2002002641A1
(en)
|
2000-06-16 |
2002-01-10 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to blys
|
|
AU2001288301A1
(en)
|
2000-08-18 |
2002-03-04 |
Human Genome Sciences, Inc. |
Binding polypeptides and methods based thereon
|
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
|
MEP21708A
(en)
|
2001-05-24 |
2010-06-10 |
Zymogenetics Inc |
Taci-immunoglobulin fusion proteins
|
|
EP1401870A4
(en)
*
|
2001-05-24 |
2006-04-19 |
Human Genome Sciences |
ANTIBODIES AGAINST TUMOR NECROSIS FACTOR DELTA (APRIL)
|
|
PL377119A1
(pl)
*
|
2001-08-03 |
2006-01-23 |
Genentech, Inc. |
Peptydy TACIs i BR3 i ich zastosowanie
|
|
US7494646B2
(en)
|
2001-09-06 |
2009-02-24 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
|
WO2003068977A2
(de)
|
2002-02-10 |
2003-08-21 |
Apoxis Sa |
Fusionkonstrukte, enthaltend aktive abschnitte von tnf-liganden
|
|
WO2003072713A2
(en)
*
|
2002-02-21 |
2003-09-04 |
Biogen Idec Ma Inc. |
Use of bcma as an immunoregulatory agent
|
|
CN1692127A
(zh)
*
|
2002-07-25 |
2005-11-02 |
健泰科生物技术公司 |
Taci抗体及其用途
|
|
WO2004094620A2
(en)
|
2003-03-28 |
2004-11-04 |
Biogen Idec Ma Inc. |
Truncated baff receptors
|
|
WO2005005462A2
(en)
*
|
2003-06-05 |
2005-01-20 |
Genentech, Inc. |
Blys antagonists and uses thereof
|
|
US20050163775A1
(en)
*
|
2003-06-05 |
2005-07-28 |
Genentech, Inc. |
Combination therapy for B cell disorders
|
|
AU2004285455A1
(en)
|
2003-10-20 |
2005-05-12 |
Biogen Idec Ma Inc. |
Therapeutic regimens for BAFF antagonists
|
|
KR101215179B1
(ko)
|
2004-04-22 |
2012-12-24 |
어젠시스 인코포레이티드 |
Steap-1 단백질과 결합하는 항체 및 그로부터 유래된분자
|
|
CN1786016B
(zh)
*
|
2004-12-09 |
2010-12-29 |
中国人民解放军军事医学科学院基础医学研究所 |
一种人工构建的生物活性分子及其制备方法
|
|
AU2005318086B2
(en)
*
|
2004-12-23 |
2011-07-07 |
Merck Serono Sa |
BCMA polypeptides and uses thereof
|
|
EP1855711B1
(en)
*
|
2005-01-28 |
2009-06-17 |
Biogen Idec MA Inc. |
USE OF BAFF TO TREAT Th2-MEDIATED CONDITIONS
|
|
CA2618763A1
(en)
|
2005-08-09 |
2007-02-15 |
Zymogenetics, Inc. |
Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules
|
|
UA93516C2
(ru)
|
2005-08-09 |
2011-02-25 |
Займоджинетикс, Инк. |
Способы лечения b-клеточных злокачественных образований c помощью слитой молекулы taci-ig
|
|
US9168286B2
(en)
|
2005-10-13 |
2015-10-27 |
Human Genome Sciences, Inc. |
Methods and compositions for use in treatment of patients with autoantibody positive disease
|
|
JP5905184B2
(ja)
|
2005-10-13 |
2016-04-20 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッドHuman Genome Sciences, Inc. |
自己抗体陽性疾患を有する患者の処置に使用するための方法および組成物
|
|
US9726673B2
(en)
|
2005-11-23 |
2017-08-08 |
Genentech, Inc. |
Methods and compositions related to B cell assays
|
|
WO2007123765A2
(en)
|
2006-03-31 |
2007-11-01 |
Human Genome Sciences Inc. |
Neutrokine-alpha and neutrokine-alpha splice variant
|
|
AR060935A1
(es)
|
2006-05-15 |
2008-07-23 |
Ares Trading Sa |
Metodos para tratar enfermedades autoinmunes utilizando una molecula de fusion taci- ig
|
|
DK2502938T3
(en)
|
2006-10-27 |
2015-04-20 |
Genentech Inc |
Antibodies and immunoconjugates and uses thereof
|
|
MD23Z
(ro)
*
|
2008-12-02 |
2010-01-31 |
Василе ЖОВМИР |
Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
|
|
MD36Z
(ro)
*
|
2008-12-02 |
2010-01-31 |
Василе ЖОВМИР |
Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
|
|
MD35Z
(ro)
*
|
2008-12-02 |
2010-01-31 |
Василе ЖОВМИР |
Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
|
|
MD24Z
(ro)
*
|
2008-12-02 |
2010-01-31 |
Василе ЖОВМИР |
Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
|
|
EP2488200A4
(en)
*
|
2009-10-14 |
2013-06-12 |
Merck Sharp & Dohme |
APRIL ANTAGONISTS AND METHOD FOR THEIR USE
|
|
UA112434C2
(uk)
|
2011-05-27 |
2016-09-12 |
Ґлаксо Ґруп Лімітед |
Антигензв'язувальний білок, який специфічно зв'язується з всма
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
WO2013171296A1
(en)
|
2012-05-16 |
2013-11-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Diagnostic and treatment of sarcoidosis
|
|
TW201425336A
(zh)
*
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
|
EP3620468A1
(en)
|
2013-02-05 |
2020-03-11 |
EngMab Sàrl |
Method for the selection of antibodies against bcma
|
|
EP2762497A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
WO2014140243A1
(en)
|
2013-03-15 |
2014-09-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and pharmaceutical composition for use in the treatment and prediction of myocardial infarction
|
|
NL2011406C2
(en)
|
2013-09-06 |
2015-03-10 |
Bionovion Holding B V |
Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides.
|
|
GB201317929D0
(en)
*
|
2013-10-10 |
2013-11-27 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
KR102173297B1
(ko)
*
|
2013-11-19 |
2020-11-03 |
리제너론 파마슈티칼스 인코포레이티드 |
인간화된 증식-유도 리간드 유전자를 가지고 있는 비-인간 동물
|
|
US20170247462A1
(en)
|
2014-07-03 |
2017-08-31 |
Oklahoma Medical Research Foundation |
Treatment of multiple sclerosis and neuromyelitis optica
|
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
EP3029068A1
(en)
|
2014-12-03 |
2016-06-08 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA for use in the treatment of diseases
|
|
NL2014108B1
(en)
|
2015-01-09 |
2016-09-30 |
Aduro Biotech Holdings Europe B V |
Altered april binding antibodies.
|
|
PL3331910T3
(pl)
|
2015-08-03 |
2020-05-18 |
Engmab Sàrl |
Przeciwciała monoklonalne przeciwko ludzkiemu antygenowi dojrzewania limfocytów B (BCMA)
|
|
HRP20201375T1
(hr)
|
2015-08-17 |
2020-11-27 |
Janssen Pharmaceutica Nv |
ANTI-BCMA ANTITIJELA, BISPECIFIČNI ANTIGEN VEŽUĆE MOLEKULE KOJE SE VEŽU ZA BCMA i CD3, I NJIHOVE UPOTREBE
|
|
CN108473575B
(zh)
*
|
2015-11-13 |
2022-04-19 |
美国卫生和人力服务部 |
抗-bcma多肽和蛋白质
|
|
PT3380522T
(pt)
|
2015-11-25 |
2024-02-14 |
Visterra Inc |
Moléculas de anticorpos contra april e suas utilizações
|
|
CN108778329B
(zh)
|
2016-02-17 |
2022-09-16 |
西雅图基因公司 |
Bcma抗体和其用以治疗癌症和免疫病症的用途
|
|
EP3471773A4
(en)
|
2016-06-21 |
2020-07-08 |
Teneobio, Inc. |
ANTIBODIES BINDING CD3
|
|
SI4050034T1
(sl)
|
2016-09-14 |
2024-07-31 |
Teneoone, Inc. |
Protitelesa, ki se vežejo na CD3
|
|
JP7267914B2
(ja)
|
2016-11-02 |
2023-05-02 |
エンクマフ エスアーエールエル |
Bcma及びcd3に対する二重特異性抗体、及び多発性骨髄腫を治療するために併用して使用される免疫療法薬
|
|
BR112019012354A2
(pt)
|
2016-12-21 |
2019-11-26 |
Teneobio Inc |
anticorpos apenas de cadeia pesada anti-bcma
|
|
MX2019011769A
(es)
|
2017-04-03 |
2019-11-07 |
Hoffmann La Roche |
Anticuerpos que se unen a steap-1.
|
|
IL312322A
(en)
|
2017-06-20 |
2024-06-01 |
Teneobio Inc |
Anti-BCMA antibodies containing only heavy chains
|
|
MX2019015563A
(es)
|
2017-06-20 |
2020-07-28 |
Teneoone Inc |
Anticuerpos anti-bcma unicamente de cadena pesada.
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
EP3793606A4
(en)
|
2018-05-16 |
2022-08-31 |
Janssen Biotech, Inc. |
METHODS OF TREATMENT OF CANCER AND ENHANCEMENT OF THE EFFECTIVENESS OF T-CELL REFERRING THERAPEUTICS
|
|
CN112384531B
(zh)
|
2018-06-01 |
2024-05-14 |
诺华股份有限公司 |
针对bcma的结合分子及其用途
|
|
AU2019297451A1
(en)
|
2018-07-03 |
2021-01-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
WO2020018922A1
(en)
|
2018-07-20 |
2020-01-23 |
Teneobio, Inc. |
Heavy chain antibodies binding to cd19
|
|
CA3130754A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
|
WO2020172605A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
|
CR20210500A
(es)
|
2019-04-05 |
2021-11-05 |
Teneobio Inc |
Anticuerpos de cadena pesada que se unen al psma
|
|
JOP20210309A1
(ar)
|
2019-05-21 |
2023-01-30 |
Novartis Ag |
جزيئات ربط بـ cd19 واستخدامتها
|
|
UA128906C2
(uk)
|
2019-06-14 |
2024-11-20 |
Тенеобіо, Інк. |
Поліспецифічні антитіла, що містять тільки важкі ланцюги, які зв'язуються з cd22 та cd3
|
|
AU2020322588A1
(en)
|
2019-07-30 |
2022-02-03 |
Jiangsu Hansoh Pharmaceutical Group Co., Ltd. |
Anti-BCMA antibody, antigen-binding fragment thereof and medical use thereof
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
CN115894703A
(zh)
|
2020-04-29 |
2023-04-04 |
特尼奥生物股份有限公司 |
具有经修饰重链恒定区的多特异性重链抗体
|
|
UY39191A
(es)
|
2020-04-29 |
2021-11-30 |
Teneobio Inc |
Anticuerpos de cadena pesada multiespecíficos con regiones constantes de cadena pesada modificadas
|
|
AU2021272291A1
(en)
|
2020-05-11 |
2023-02-02 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma
|
|
MX2022014995A
(es)
*
|
2020-05-29 |
2023-02-09 |
Chinook Therapeutics Inc |
Metodos de tratamiento de la nefropatia por iga con un anticuerpo de union a april.
|
|
PE20230464A1
(es)
|
2020-06-30 |
2023-03-14 |
Teneobio Inc |
Union de anticuerpos multiespecificos a bcma
|
|
IL305144A
(en)
|
2021-02-16 |
2023-10-01 |
Janssen Pharmaceutica Nv |
Trispecific antibodies targeting BCMA, GPRC5D and CD3
|
|
CA3214757A1
(en)
|
2021-04-08 |
2022-10-13 |
Andreas Loew |
Multifuntional molecules binding to tcr and uses thereof
|
|
TW202309522A
(zh)
|
2021-05-11 |
2023-03-01 |
美商健生生物科技公司 |
用於監測復發性及/或難治性多發性骨髓瘤之治療的方法及組成物
|
|
CN118678963A
(zh)
|
2021-08-11 |
2024-09-20 |
艾克索生物制药有限公司 |
使用sBCMA变体及其FC融合蛋白减少IgA、IgM和/或IgG的产生的方法
|
|
IL312503A
(en)
|
2021-11-03 |
2024-07-01 |
Janssen Biotech Inc |
Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
|
|
TW202440636A
(zh)
|
2023-03-21 |
2024-10-16 |
美商傳記55有限公司 |
Cd19/cd38多特異性抗體
|
|
WO2025134049A1
(en)
|
2023-12-21 |
2025-06-26 |
Janssen Biotech, Inc |
Trispecific antibody targeting bcma, gprc5d and cd3 for the treatment of al amyloidosis
|
|
WO2025134050A1
(en)
|
2023-12-21 |
2025-06-26 |
Janssen Biotech, Inc |
Trispecific antibody targeting bcma, gprc5d and cd3 for the treatment of multiple myeloma
|
|
WO2025174963A1
(en)
|
2024-02-16 |
2025-08-21 |
Kite Pharma, Inc. |
Systems, methods, and kits for generating and administering engineered t cells and cd38 targeting compounds as a combination therapy
|