RO77170A - Procedeu de preparare a unor derivati de 3(2-hidroxi)-4-substituit-fenil-cicloalchenone,cicloalchenol,cicloalcanone si cicloalcanoli - Google Patents

Procedeu de preparare a unor derivati de 3(2-hidroxi)-4-substituit-fenil-cicloalchenone,cicloalchenol,cicloalcanone si cicloalcanoli

Info

Publication number
RO77170A
RO77170A RO7898208A RO9820878A RO77170A RO 77170 A RO77170 A RO 77170A RO 7898208 A RO7898208 A RO 7898208A RO 9820878 A RO9820878 A RO 9820878A RO 77170 A RO77170 A RO 77170A
Authority
RO
Romania
Prior art keywords
subtitu
cycloalkenoles
cycloalkanoles
cycloalkenones
cycloalkanones
Prior art date
Application number
RO7898208A
Other languages
English (en)
French (fr)
Inventor
Charles A Herbert
Michael R Johnson
Lawrence S Molvin
Original Assignee
Pfizer Inc,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc,Us filed Critical Pfizer Inc,Us
Publication of RO77170A publication Critical patent/RO77170A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C07C37/0555—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group being esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/42—Halogenated derivatives containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C07C41/50—Preparation of compounds having groups by reactions producing groups
    • C07C41/56—Preparation of compounds having groups by reactions producing groups by condensation of aldehydes, paraformaldehyde, or ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/95—Esters of quinone carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
RO7898208A 1977-09-13 1978-09-13 Procedeu de preparare a unor derivati de 3(2-hidroxi)-4-substituit-fenil-cicloalchenone,cicloalchenol,cicloalcanone si cicloalcanoli RO77170A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83310277A 1977-09-13 1977-09-13

Publications (1)

Publication Number Publication Date
RO77170A true RO77170A (ro) 1981-06-22

Family

ID=25263433

Family Applications (5)

Application Number Title Priority Date Filing Date
RO7898208A RO77170A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a unor derivati de 3(2-hidroxi)-4-substituit-fenil-cicloalchenone,cicloalchenol,cicloalcanone si cicloalcanoli
RO7899162A RO76721A (ro) 1977-09-13 1978-09-13 Procedeu pentru prepararea 3.12.-hidroxi-4-fenil-cicloalcanonei
RO7898207A RO77321A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a unor derivati de 3(2-hidroxi-4-substituit-fenil)-cicloalcanone
RO7898209A RO77296A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a umor derivati de 3(2-hidroxi)-4-substituit-fenilcicloalcanone
RO7898210A RO77297A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a unor derivati de 3(2-hidroxi-4-substituit)-fenilcicloalchenali si cicloalcanol

Family Applications After (4)

Application Number Title Priority Date Filing Date
RO7899162A RO76721A (ro) 1977-09-13 1978-09-13 Procedeu pentru prepararea 3.12.-hidroxi-4-fenil-cicloalcanonei
RO7898207A RO77321A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a unor derivati de 3(2-hidroxi-4-substituit-fenil)-cicloalcanone
RO7898209A RO77296A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a umor derivati de 3(2-hidroxi)-4-substituit-fenilcicloalcanone
RO7898210A RO77297A (ro) 1977-09-13 1978-09-13 Procedeu de preparare a unor derivati de 3(2-hidroxi-4-substituit)-fenilcicloalchenali si cicloalcanol

Country Status (11)

Country Link
JP (4) JPS5538367A (ro)
BE (1) BE870404A (ro)
CS (1) CS216502B2 (ro)
DD (3) DD148631A5 (ro)
HU (1) HU181937B (ro)
PL (5) PL122834B1 (ro)
PT (1) PT68543A (ro)
RO (5) RO77170A (ro)
SU (1) SU991944A3 (ro)
YU (1) YU215478A (ro)
ZA (1) ZA785180B (ro)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486609A (en) * 1981-03-16 1984-12-04 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4831059A (en) * 1980-09-19 1989-05-16 Pfizer Inc. Producing analgesia with pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes derivatives
US4921994A (en) * 1980-09-19 1990-05-01 Pfizer Inc. Pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes and derivatives thereof
US4835192A (en) * 1980-09-19 1989-05-30 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4933475A (en) * 1980-09-19 1990-06-12 Pfizer, Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4285867A (en) 1980-09-19 1981-08-25 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4331602A (en) 1980-09-19 1982-05-25 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted]phenyl)naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4591225A (en) * 1985-01-14 1986-05-27 Molex Incorporated Arrangement for interconnecting a printed circuit board with a multi-conductor cable
GB9007762D0 (en) * 1990-04-05 1990-06-06 Beecham Group Plc Novel compounds
CA2823724A1 (en) * 2006-04-24 2007-11-08 Allergan, Inc. Abnormal cannabidiols as agents for lowering intraocular pressure
UA101004C2 (en) * 2007-12-13 2013-02-25 Теракос, Инк. Derivatives of benzylphenylcyclohexane and use thereof

Also Published As

Publication number Publication date
JPS5930692B2 (ja) 1984-07-28
RO77296A (ro) 1981-06-22
PL122765B1 (en) 1982-08-31
RO77321A (ro) 1981-08-17
DD148334A5 (de) 1981-05-20
PT68543A (en) 1978-10-01
JPS5930693B2 (ja) 1984-07-28
JPS5753352B2 (ro) 1982-11-12
PL121079B1 (en) 1982-04-30
RO76721A (ro) 1982-10-11
ZA785180B (en) 1979-08-29
DD140454A5 (de) 1980-03-05
BE870404A (fr) 1979-03-12
JPS5639036A (en) 1981-04-14
PL122834B1 (en) 1982-08-31
CS216502B2 (en) 1982-11-26
SU991944A3 (ru) 1983-01-23
JPS5639035A (en) 1981-04-14
RO77297A (ro) 1981-06-22
PL209554A1 (pl) 1979-06-04
PL122835B1 (en) 1982-08-31
YU215478A (en) 1983-06-30
PL123771B1 (en) 1982-11-30
DD148631A5 (de) 1981-06-03
JPS5538367A (en) 1980-03-17
JPS5639031A (en) 1981-04-14
HU181937B (en) 1983-11-28
JPS605579B2 (ja) 1985-02-12

Similar Documents

Publication Publication Date Title
RO84151A (ro) Procedeu de preparare a unor derivati de penicilanoilo0imetilpenicilanat 1,1-dio0id
LU78861A1 (fr) Procede de preparation de nouveaux derives steroides 4,9-dieniques 11beta-substitues
RO79720A (ro) Procedeu de preparare a unor 2-penem derivati
BE854047A (fr) Derives de 1,2 dihydronaphtalene et leur procede de preparation
RO78632A (ro) Procedeu de preparare a unor derivati de indanil
LU78859A1 (fr) Procede de preparation de nouveaux derives steroides 11beta-substitues 1,3,5(10)-trieniques
RO76087A (ro) Procedeu de preparare a unor derivati ai guanidinei
RO77170A (ro) Procedeu de preparare a unor derivati de 3(2-hidroxi)-4-substituit-fenil-cicloalchenone,cicloalchenol,cicloalcanone si cicloalcanoli
RO79048A (ro) Procedeu pentru prepararea unor derivati de 5,11-dihidro-6h-pirido-(2,3b)-(1,4)-benzodiazepin-6-ona
RO81685A (ro) Procedeu de preparare a unor derivati de antrachinonsulfonamide cu formula generala i
PT68991A (fr) Procede de preparation de derives de thiazolidinedione-2,4
PT67958B (fr) Procede de preparation de derives de pyridazinone
PT66819A (fr) Procede de preparation de n-(1'-allyl 2'-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamida et ses derives
LU78874A1 (fr) Procede de preparation de nouvelles sulfonylhydrazones de 1,4-dioxo-et 4-oxoquinoxaline-2-carboxaldehyde
RO81622A (ro) Procedeu de preparare a unor derivati de 4"-dezoxi-4"-aminoaritromicina a
BE845327A (fr) Procede de preparation de 4,4'-dihydroxy-3-3'-5-5'-tretralcoyldiphenylalcanes
BE866662A (fr) Procede de preparation de 3,5-dihalogenanilines
FR2319615A1 (fr) Procede de preparation de cyclohexane-diones-1,3
PT67729A (fr) Procede de preparation de nouveaux derives de l'oxadiazole-1,3,4 et de compositions iongicides qui en contiennent
RO76179A (ro) Procedeu de preparare a derivatilor de di si tricloracetamida
PT67685B (fr) Procede de preparation de derives 17alpha-acetyleniques del'androst-4-ene
FR2351967A1 (fr) Procede de preparation de derives de 3-benzazepines
RO85269A (ro) Procedeu de preparare a unor derivati de 1,2,4-ozadiazina
RO75249A (ro) Procedeu pentru prepararea unor derivati de n-(1,3,4-triadiazol-2-ol)-benzamide
FR2321479A1 (fr) Procede de preparation de dinitro-2,4 aniline