RO120268B1 - Vaccin polienv, pentru virusul imunodeficienţei umane - Google Patents

Vaccin polienv, pentru virusul imunodeficienţei umane Download PDF

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Publication number
RO120268B1
RO120268B1 RO98-01218A RO9801218A RO120268B1 RO 120268 B1 RO120268 B1 RO 120268B1 RO 9801218 A RO9801218 A RO 9801218A RO 120268 B1 RO120268 B1 RO 120268B1
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RO
Romania
Prior art keywords
vaccine
hiv
recombinant
env
protein
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RO98-01218A
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English (en)
Romanian (ro)
Inventor
Julia Hurwitz
Christopher Coleclough
Randall Owens
Karen Slobod
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St. Jude Children's Research Hospital
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Publication date
Application filed by St. Jude Children's Research Hospital filed Critical St. Jude Children's Research Hospital
Publication of RO120268B1 publication Critical patent/RO120268B1/ro

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16HIV-1 ; HIV-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24171Demonstrated in vivo effect
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RO98-01218A 1996-01-23 1997-01-23 Vaccin polienv, pentru virusul imunodeficienţei umane RO120268B1 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/590,288 US5741492A (en) 1996-01-23 1996-01-23 Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses
PCT/US1997/000669 WO1997027311A1 (en) 1996-01-23 1997-01-23 Mixture of recombinant vaccinia vectors as polyenv vaccines for hiv

Publications (1)

Publication Number Publication Date
RO120268B1 true RO120268B1 (ro) 2005-11-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RO98-01218A RO120268B1 (ro) 1996-01-23 1997-01-23 Vaccin polienv, pentru virusul imunodeficienţei umane

Country Status (28)

Country Link
US (3) US5741492A (OSRAM)
EP (2) EP0876498B1 (OSRAM)
JP (2) JP2000504326A (OSRAM)
KR (1) KR100571479B1 (OSRAM)
CN (1) CN1229501C (OSRAM)
AP (1) AP1200A (OSRAM)
AT (1) ATE278790T1 (OSRAM)
AU (1) AU709174B2 (OSRAM)
BG (1) BG64711B1 (OSRAM)
BR (1) BR9707611A (OSRAM)
CA (1) CA2243570C (OSRAM)
CZ (1) CZ296575B6 (OSRAM)
DE (1) DE69731075T2 (OSRAM)
DK (1) DK0876498T3 (OSRAM)
EA (1) EA002390B1 (OSRAM)
ES (1) ES2230596T3 (OSRAM)
GE (1) GEP20032902B (OSRAM)
HU (2) HU0402182D0 (OSRAM)
IL (2) IL125497A (OSRAM)
NO (1) NO322261B1 (OSRAM)
NZ (1) NZ331024A (OSRAM)
OA (1) OA10814A (OSRAM)
PL (1) PL188641B1 (OSRAM)
PT (1) PT876498E (OSRAM)
RO (1) RO120268B1 (OSRAM)
TR (1) TR199801418T2 (OSRAM)
UA (1) UA73712C2 (OSRAM)
WO (1) WO1997027311A1 (OSRAM)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116981448A (zh) * 2021-01-14 2023-10-31 益生生物科技有限公司 包括工程化的植物来源的细胞外囊泡的组合物及其用作疫苗的用途

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IL156919A0 (en) 2004-02-08
KR19990081931A (ko) 1999-11-15
CN1214083A (zh) 1999-04-14
NZ331024A (en) 2000-02-28
DE69731075D1 (de) 2004-11-11
AP1200A (en) 2003-08-29
HK1016218A1 (en) 1999-10-29
AU1829997A (en) 1997-08-20
DK0876498T3 (da) 2005-02-07
EA002390B1 (ru) 2002-04-25
US5846546A (en) 1998-12-08
JP2000504326A (ja) 2000-04-11
HUP9900389A2 (hu) 1999-06-28
EP0876498B1 (en) 2004-10-06
JP2007259870A (ja) 2007-10-11
EA199800638A1 (ru) 1999-02-25
PL328193A1 (en) 1999-01-18
AU709174B2 (en) 1999-08-26
DE69731075T2 (de) 2006-03-09
NO983377D0 (no) 1998-07-22
HU224344B1 (hu) 2005-08-29
CN1229501C (zh) 2005-11-30
IL125497A0 (en) 1999-03-12
US6086891A (en) 2000-07-11
OA10814A (en) 2003-01-28
GEP20032902B (en) 2003-02-25
PT876498E (pt) 2005-02-28
EP1378516A1 (en) 2004-01-07
CA2243570A1 (en) 1997-07-31
HU0402182D0 (en) 2004-12-28
US5741492A (en) 1998-04-21
NO322261B1 (no) 2006-09-04
HUP9900389A3 (en) 2001-06-28
BG64711B1 (bg) 2005-12-30
BG102712A (en) 1999-04-30
KR100571479B1 (ko) 2007-06-07
PL188641B1 (pl) 2005-03-31
NO983377L (no) 1998-09-23
WO1997027311A1 (en) 1997-07-31
EP0876498A1 (en) 1998-11-11
AP9801325A0 (en) 1998-09-30
ATE278790T1 (de) 2004-10-15
CZ296575B6 (cs) 2006-04-12
CA2243570C (en) 2001-08-14
UA73712C2 (en) 2005-09-15
ES2230596T3 (es) 2005-05-01
IL125497A (en) 2007-07-04
CZ229398A3 (cs) 1998-12-16
TR199801418T2 (xx) 1998-10-21
BR9707611A (pt) 1999-07-27

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