RO110905B - Compozitie farmaceutica, antihipertensiva - Google Patents

Compozitie farmaceutica, antihipertensiva Download PDF

Info

Publication number
RO110905B
RO110905B RO92-0990A RO9200990A RO110905B RO 110905 B RO110905 B RO 110905B RO 9200990 A RO9200990 A RO 9200990A RO 110905 B RO110905 B RO 110905B
Authority
RO
Romania
Prior art keywords
composition according
atoms
alkyl
pyridazodiazepine
formula
Prior art date
Application number
RO92-0990A
Other languages
English (en)
Romanian (ro)
Inventor
Clozel Jean-Paul
Muller Rita
Osterrieder Wolfgang
Original Assignee
Hoffmann La Roche Ag Basle F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche Ag Basle F filed Critical Hoffmann La Roche Ag Basle F
Publication of RO110905B publication Critical patent/RO110905B/ro

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
RO92-0990A 1991-07-23 1992-07-21 Compozitie farmaceutica, antihipertensiva RO110905B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH219191 1991-07-23

Publications (1)

Publication Number Publication Date
RO110905B true RO110905B (ro) 1996-05-30

Family

ID=4228024

Family Applications (1)

Application Number Title Priority Date Filing Date
RO92-0990A RO110905B (ro) 1991-07-23 1992-07-21 Compozitie farmaceutica, antihipertensiva

Country Status (31)

Country Link
US (1) US5620975A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0524512B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0680009B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100260479B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1040505C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE260661T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU656207B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG60949B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9202830A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2074039C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ281691B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE59209993D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0524512T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2215160T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HR (1) HRP930953B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU214029B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE922378A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL102541A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IS (1) IS3887A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9204212A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY118064A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO301047B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ243577A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT524512E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO110905B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2084225C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK278918B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW216770B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UY (1) UY23449A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (2) YU49198B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA925322B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT634175E (pt) * 1993-07-15 2001-06-29 Hoffmann La Roche Combinacao farmaceutica que contem um inibidor do sistema renina-angiotensina e o antagonista de endotelina
IL131816A (en) 1997-04-04 2003-06-24 Exxon Res & Engineering Compan Composite structures having high containment strength
EP1438297A1 (en) * 2001-10-10 2004-07-21 Aryx Therapeutics Mibefradil-based compounds as calcium channel blockers useful in the treatment of hypertension and angina
US7687086B1 (en) 2003-02-28 2010-03-30 University Of Portland Method for obtaining taxanes
RU2282443C1 (ru) * 2004-12-29 2006-08-27 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственное средство, обладающее антигипертензивным действием, и способ его изготовления
EP2537534B1 (en) 2011-06-22 2014-12-17 Hexal AG Esters of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their therapeutic use.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
CA1319144C (en) * 1986-11-14 1993-06-15 Quirico Branca Tetrahydronaphthalene derivatives
FR2607004B1 (fr) * 1986-11-20 1990-06-01 Synthelabo Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine
US5110813A (en) * 1987-09-15 1992-05-05 Alcoholism And Drug Addiction Research Foundation Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors
US4871731A (en) * 1987-10-07 1989-10-03 Marion Laboratories, Inc. Captopril and diltiazem composition and the like
KR940005408B1 (ko) * 1990-12-03 1994-06-18 만도기계 주식회사 파워 윈도우 모우터 회전자의 선단부 흔들림 측정장치

Also Published As

Publication number Publication date
MY118064A (en) 2004-08-30
JPH0680009B2 (ja) 1994-10-12
EP0524512A2 (de) 1993-01-27
EP0524512B1 (de) 2004-03-03
KR930001910A (ko) 1993-02-22
EP0524512A3 (en) 1993-09-01
SK227092A3 (en) 1996-02-07
IL102541A0 (en) 1993-01-14
KR100260479B1 (ko) 2000-07-01
IL102541A (en) 1995-12-08
HUT62792A (en) 1993-06-28
MX9204212A (es) 1993-08-01
HU9202367D0 (en) 1992-10-28
NO922903D0 (no) 1992-07-22
BG60949B1 (bg) 1996-07-31
ES2215160T3 (es) 2004-10-01
HRP930953B1 (en) 2003-06-30
ATE260661T1 (de) 2004-03-15
IS3887A (is) 1993-01-24
YU49198B (sh) 2004-09-03
BR9202830A (pt) 1993-03-23
YU72392A (sh) 1997-05-28
RU2084225C1 (ru) 1997-07-20
CA2074039A1 (en) 1993-01-24
CZ281691B6 (cs) 1996-12-11
AU656207B2 (en) 1995-01-27
PT524512E (pt) 2004-07-30
UY23449A1 (es) 1993-01-21
CA2074039C (en) 2004-11-02
JPH05194217A (ja) 1993-08-03
HRP930953A2 (en) 1995-10-31
IE922378A1 (en) 1993-01-27
DE59209993D1 (de) 2004-04-08
CN1068737A (zh) 1993-02-10
ZA925322B (en) 1993-03-31
NZ243577A (en) 1994-09-27
DK0524512T3 (da) 2004-07-05
NO301047B1 (no) 1997-09-08
SK278918B6 (sk) 1998-04-08
CN1040505C (zh) 1998-11-04
NO922903L (no) 1993-01-25
TW216770B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-12-01
AU2041692A (en) 1993-01-28
BG96664A (bg) 1993-12-24
HU214029B (en) 1997-12-29
CZ227092A3 (en) 1993-02-17
US5620975A (en) 1997-04-15

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