RO110493B1 - Derivati de benzimidazol si procedee pentru prepararea acestora - Google Patents
Derivati de benzimidazol si procedee pentru prepararea acestora Download PDFInfo
- Publication number
- RO110493B1 RO110493B1 RO92-01581A RO9201581A RO110493B1 RO 110493 B1 RO110493 B1 RO 110493B1 RO 9201581 A RO9201581 A RO 9201581A RO 110493 B1 RO110493 B1 RO 110493B1
- Authority
- RO
- Romania
- Prior art keywords
- methyl
- benzimidazole
- dimethoxy
- sulfinyl
- pyridinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9002206A SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | New compounds |
PCT/SE1991/000415 WO1991019711A1 (fr) | 1990-06-20 | 1991-06-11 | Benzimidazoles substitues, procede de preparation et utilisation pharmaceutique de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
RO110493B1 true RO110493B1 (ro) | 1996-01-30 |
Family
ID=20379831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO92-01581A RO110493B1 (ro) | 1990-06-20 | 1991-06-11 | Derivati de benzimidazol si procedee pentru prepararea acestora |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0535081A1 (fr) |
JP (1) | JPH05507713A (fr) |
CN (1) | CN1058212A (fr) |
AP (1) | AP215A (fr) |
AU (1) | AU649453B2 (fr) |
BG (1) | BG97200A (fr) |
CA (1) | CA2083714A1 (fr) |
CZ (1) | CZ279772B6 (fr) |
FI (1) | FI925766A0 (fr) |
HU (1) | HUT62881A (fr) |
IE (1) | IE912025A1 (fr) |
IL (1) | IL98470A0 (fr) |
IS (1) | IS3721A7 (fr) |
LT (2) | LT3952B (fr) |
LV (1) | LV10953A (fr) |
MA (1) | MA22199A1 (fr) |
NO (1) | NO924775L (fr) |
NZ (1) | NZ238546A (fr) |
OA (1) | OA09682A (fr) |
PT (1) | PT98035A (fr) |
RO (1) | RO110493B1 (fr) |
SE (1) | SE9002206D0 (fr) |
TN (1) | TNSN91049A1 (fr) |
TW (1) | TW216418B (fr) |
WO (1) | WO1991019711A1 (fr) |
YU (1) | YU104191A (fr) |
ZA (2) | ZA914297B (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
SE9103776D0 (sv) * | 1991-12-19 | 1991-12-19 | Astra Ab | New compounds |
IS4232A (is) * | 1993-12-06 | 1995-06-07 | Astra Aktiebolag | Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun |
SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
PT1257269E (pt) | 2000-02-24 | 2005-03-31 | Kopran Res Lab Ltd | Derivados do benzimidazole anti-ulcera estavel em relacao ao acido de administracao oral |
SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
US7906145B2 (en) | 2002-04-09 | 2011-03-15 | Flamel Technologies | Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s) |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
JP4919801B2 (ja) | 2003-09-26 | 2012-04-18 | アルザ・コーポレーシヨン | 高い薬剤配合量を提供する薬剤コーティング及びそれを提供する方法 |
TW200606163A (en) | 2004-04-22 | 2006-02-16 | Eisai Co Ltd | Imidazopyridine compound |
US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
US20070015782A1 (en) | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
US9040564B2 (en) | 2005-04-28 | 2015-05-26 | Eisai R&D Management Co., Ltd. | Stabilized composition |
US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
WO2007122686A1 (fr) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | Composes benzimidazole |
EP2046334B1 (fr) | 2006-07-25 | 2014-05-21 | Vecta Ltd. | Compositions et procédés d'inhibition de sécrétion d'acide gastrique utilisant des dérivés de petits acides dicarboxyliques combinés á un ipp |
JP5492417B2 (ja) * | 2006-10-13 | 2014-05-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 胃酸分泌抑制作用を有するベンズイミダゾール化合物 |
CN102209529A (zh) | 2008-09-09 | 2011-10-05 | 阿斯利康(瑞典)有限公司 | 将药物组合物递送至有需要的患者的方法 |
EP2445499A4 (fr) | 2009-06-25 | 2013-02-27 | Astrazeneca Ab | Procede pour le traitement d'un patient a risque de developer un ulcere associe a nsaid |
WO2011080500A2 (fr) | 2009-12-29 | 2011-07-07 | Orexo Ab | Nouvelle forme pharmaceutique destinée au traitement de troubles liés à l'acide gastrique |
WO2011080502A2 (fr) | 2009-12-29 | 2011-07-07 | Orexo Ab | Nouvelle forme pharmaceutique destinée au traitement de troubles liés à l'acide gastrique |
US20120294937A1 (en) | 2009-12-29 | 2012-11-22 | Novartis Ag | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
EP2601947A1 (fr) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Combinaison à dose fixe pour le traitement de maladies associées à Hélicobacter pylori |
WO2013101897A2 (fr) | 2011-12-28 | 2013-07-04 | Pozen Inc. | Compositions et procédés d'administration d'oméprazole plus acide acétylsalicylique améliorés |
TWI659022B (zh) * | 2016-09-14 | 2019-05-11 | 國立臺灣大學 | 作為d-胺基酸氧化酶(daao)抑制劑之新穎經取代苯并咪唑衍生物 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE418966B (sv) | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
IN148930B (fr) | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
CH644116A5 (de) | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
US4738975A (en) | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
NZ222495A (en) | 1986-11-21 | 1991-04-26 | Haessle Ab | Benzimidazole derivatives and pharmaceutical compositions |
DE3722810A1 (de) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung |
JPH02501930A (ja) * | 1987-10-30 | 1990-06-28 | アクチエボラゲツト・ヘツスレ | 薬学的化合物のための新規な用途 |
AU2817989A (en) * | 1987-12-11 | 1989-07-05 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel benzimidazole derivatives |
WO1989011479A1 (fr) * | 1988-05-25 | 1989-11-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Nouveaux composes fluores d'alkoxyde |
-
1990
- 1990-06-20 SE SE9002206A patent/SE9002206D0/xx unknown
-
1991
- 1991-06-05 ZA ZA914297A patent/ZA914297B/xx unknown
- 1991-06-05 ZA ZA914296A patent/ZA914296B/xx unknown
- 1991-06-11 CA CA002083714A patent/CA2083714A1/fr not_active Abandoned
- 1991-06-11 EP EP91911659A patent/EP0535081A1/fr not_active Withdrawn
- 1991-06-11 HU HU924033A patent/HUT62881A/hu unknown
- 1991-06-11 RO RO92-01581A patent/RO110493B1/ro unknown
- 1991-06-11 AU AU80097/91A patent/AU649453B2/en not_active Ceased
- 1991-06-11 JP JP91511435A patent/JPH05507713A/ja active Pending
- 1991-06-11 WO PCT/SE1991/000415 patent/WO1991019711A1/fr not_active Application Discontinuation
- 1991-06-12 IL IL98470A patent/IL98470A0/xx unknown
- 1991-06-12 TW TW080104582A patent/TW216418B/zh active
- 1991-06-12 YU YU104191A patent/YU104191A/sh unknown
- 1991-06-14 IE IE202591A patent/IE912025A1/en unknown
- 1991-06-14 NZ NZ238546A patent/NZ238546A/en unknown
- 1991-06-18 MA MA22462A patent/MA22199A1/fr unknown
- 1991-06-19 TN TNTNSN91049A patent/TNSN91049A1/fr unknown
- 1991-06-19 AP APAP/P/1991/000285A patent/AP215A/en active
- 1991-06-19 PT PT98035A patent/PT98035A/pt not_active Application Discontinuation
- 1991-06-20 CZ CS911894A patent/CZ279772B6/cs unknown
- 1991-06-20 IS IS3721A patent/IS3721A7/is unknown
- 1991-06-20 CN CN91105024A patent/CN1058212A/zh active Pending
-
1992
- 1992-11-27 OA OA60306A patent/OA09682A/en unknown
- 1992-12-10 NO NO92924775A patent/NO924775L/no unknown
- 1992-12-18 FI FI925766A patent/FI925766A0/fi not_active Application Discontinuation
- 1992-12-18 BG BG097200A patent/BG97200A/bg unknown
-
1993
- 1993-08-27 LV LV931045A patent/LV10953A/xx unknown
- 1993-12-30 LT LTIP1712A patent/LT3952B/lt not_active IP Right Cessation
- 1993-12-30 LT LTIP1713A patent/LT3977B/lt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1991019711A1 (fr) | 1991-12-26 |
SE9002206D0 (sv) | 1990-06-20 |
HUT62881A (en) | 1993-06-28 |
EP0535081A1 (fr) | 1993-04-07 |
LV10953A (lv) | 1995-12-20 |
IS3721A7 (is) | 1991-12-21 |
YU104191A (sh) | 1994-01-20 |
FI925766A (fi) | 1992-12-18 |
AP9100285A0 (en) | 1991-07-31 |
LT3977B (en) | 1996-06-25 |
CA2083714A1 (fr) | 1991-12-21 |
TW216418B (fr) | 1993-11-21 |
ZA914296B (en) | 1992-03-25 |
HU9204033D0 (en) | 1993-03-29 |
PT98035A (pt) | 1992-03-31 |
CZ279772B6 (cs) | 1995-06-14 |
BG97200A (bg) | 1993-12-24 |
OA09682A (en) | 1993-05-15 |
AU8009791A (en) | 1992-01-07 |
LT3952B (en) | 1996-05-27 |
AP215A (en) | 1992-09-02 |
NZ238546A (en) | 1994-03-25 |
LTIP1713A (en) | 1995-08-25 |
CS189491A3 (en) | 1992-04-15 |
IE912025A1 (en) | 1992-01-01 |
MA22199A1 (fr) | 1992-04-01 |
LTIP1712A (en) | 1995-08-25 |
TNSN91049A1 (fr) | 1992-10-25 |
FI925766A0 (fi) | 1992-12-18 |
ZA914297B (en) | 1992-03-25 |
AU649453B2 (en) | 1994-05-26 |
CN1058212A (zh) | 1992-01-29 |
NO924775D0 (no) | 1992-12-10 |
NO924775L (no) | 1992-12-10 |
IL98470A0 (en) | 1992-07-15 |
JPH05507713A (ja) | 1993-11-04 |
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