LTIP1712A - Substituted benzimidazoles, process for their preparation and their pharmaceutical use - Google Patents

Substituted benzimidazoles, process for their preparation and their pharmaceutical use

Info

Publication number
LTIP1712A
LTIP1712A LTIP1712A LTIP1712A LTIP1712A LT IP1712 A LTIP1712 A LT IP1712A LT IP1712 A LTIP1712 A LT IP1712A LT IP1712 A LTIP1712 A LT IP1712A LT IP1712 A LTIP1712 A LT IP1712A
Authority
LT
Lithuania
Prior art keywords
preparation
pharmaceutical use
substituted benzimidazoles
benzimidazoles
substituted
Prior art date
Application number
LTIP1712A
Inventor
Arne Elof Braendstroem
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of LTIP1712A publication Critical patent/LTIP1712A/en
Publication of LT3952B publication Critical patent/LT3952B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
LTIP1712A 1990-06-20 1993-12-30 Substituted benzimidazoles, process for their preparation and their pharmaceutical use LT3952B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002206A SE9002206D0 (en) 1990-06-20 1990-06-20 NEW COMPOUNDS

Publications (2)

Publication Number Publication Date
LTIP1712A true LTIP1712A (en) 1995-08-25
LT3952B LT3952B (en) 1996-05-27

Family

ID=20379831

Family Applications (2)

Application Number Title Priority Date Filing Date
LTIP1713A LT3977B (en) 1990-06-20 1993-12-30 Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
LTIP1712A LT3952B (en) 1990-06-20 1993-12-30 Substituted benzimidazoles, process for their preparation and their pharmaceutical use

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTIP1713A LT3977B (en) 1990-06-20 1993-12-30 Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use

Country Status (27)

Country Link
EP (1) EP0535081A1 (en)
JP (1) JPH05507713A (en)
CN (1) CN1058212A (en)
AP (1) AP215A (en)
AU (1) AU649453B2 (en)
BG (1) BG97200A (en)
CA (1) CA2083714A1 (en)
CZ (1) CZ279772B6 (en)
FI (1) FI925766A0 (en)
HU (1) HUT62881A (en)
IE (1) IE912025A1 (en)
IL (1) IL98470A0 (en)
IS (1) IS3721A7 (en)
LT (2) LT3977B (en)
LV (1) LV10953A (en)
MA (1) MA22199A1 (en)
NO (1) NO924775L (en)
NZ (1) NZ238546A (en)
OA (1) OA09682A (en)
PT (1) PT98035A (en)
RO (1) RO110493B1 (en)
SE (1) SE9002206D0 (en)
TN (1) TNSN91049A1 (en)
TW (1) TW216418B (en)
WO (1) WO1991019711A1 (en)
YU (1) YU104191A (en)
ZA (2) ZA914297B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002043D0 (en) * 1990-06-07 1990-06-07 Astra Ab IMPROVED METHOD FOR SYNTHESIS
SE9103776D0 (en) * 1991-12-19 1991-12-19 Astra Ab NEW COMPOUNDS
IS4232A (en) * 1993-12-06 1995-06-07 Astra Aktiebolag Substituted benzimidazole, its methods of manufacture and pharmacological use
SE9500422D0 (en) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (en) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
SE9600070D0 (en) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
DK1257269T3 (en) 2000-02-24 2005-03-14 Kopran Res Lab Ltd Acid-stable benzimidazole derivatives for oral administration against ulcer
SE0101379D0 (en) 2001-04-18 2001-04-18 Diabact Ab Composition that inhibits gastric acid secretion
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
CA2480826C (en) 2002-04-09 2012-02-07 Flamel Technologies Oral pharmaceutical formulation in the form of microcapsule aqueous suspension allowing modified release of active ingredient(s)
SE0203065D0 (en) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
ATE544447T1 (en) 2003-09-26 2012-02-15 Alza Corp MEDICINAL COATING WITH A HIGH ACTIVE INGREDIENTS CONTENT AND METHODS FOR THE PRODUCTION THEREOF
TW200606163A (en) 2004-04-22 2006-02-16 Eisai Co Ltd Imidazopyridine compound
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070015782A1 (en) * 2005-04-15 2007-01-18 Eisai Co., Ltd. Benzimidazole compound
US9040564B2 (en) 2005-04-28 2015-05-26 Eisai R&D Management Co., Ltd. Stabilized composition
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
WO2007122686A1 (en) * 2006-04-14 2007-11-01 Eisai R & D Management Co., Ltd. Benzimidazole compounds
RU2467747C2 (en) 2006-07-25 2012-11-27 Векта Лтд. Compositions and methods for gastric acid secretion inhibition with using small dicarboxylic acid derivatives in combination with ppi
EP2065379A4 (en) * 2006-10-13 2011-01-19 Eisai R&D Man Co Ltd Benzimidazole compound having gastric acid secretion inhibitory activity
CA2736547C (en) 2008-09-09 2016-11-01 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080501A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (en) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Fixed-dose combination for treatment of helicobacter pylori associated diseases
MX2014007935A (en) 2011-12-28 2014-11-14 Pozen Inc Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid.
KR102409502B1 (en) * 2016-09-14 2022-06-16 위펑 제인 쳉 Novel substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (en) 1974-02-18 1981-07-06 Haessle Ab ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects
SE416649B (en) 1974-05-16 1981-01-26 Haessle Ab PROCEDURE FOR THE PREPARATION OF SUBSTANCES WHICH PREVENT Gastric acid secretion
IN148930B (en) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (en) 1978-04-14 1979-10-15 Haessle Ab Gastric acid secretion
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (en) 1980-08-21 1984-07-13 Hoffmann La Roche IMIDAZOLE DERIVATIVES.
SE8300736D0 (en) 1983-02-11 1983-02-11 Haessle Ab NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS
SE8301182D0 (en) 1983-03-04 1983-03-04 Haessle Ab NOVEL COMPOUNDS
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US4738975A (en) 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (en) * 1985-10-29 1985-10-29 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
DE3722810A1 (en) * 1987-07-10 1989-01-19 Hoechst Ag SUBSTITUTED BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THE USE THEREOF
WO1989003830A1 (en) * 1987-10-30 1989-05-05 Aktiebolaget Hässle 2-pyridinylmethyl (sulfinyl or thio)benzimidazoles for treatment of diseases related to bone loss
ZA889194B (en) * 1987-12-11 1989-08-30 Byk Gulden Lomberg Chemisch Fa Novel benzimidazole derivatives
JPH03504497A (en) * 1988-05-25 1991-10-03 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング New fluoroalkoxy compound

Also Published As

Publication number Publication date
ZA914296B (en) 1992-03-25
IE912025A1 (en) 1992-01-01
YU104191A (en) 1994-01-20
AP215A (en) 1992-09-02
NZ238546A (en) 1994-03-25
TW216418B (en) 1993-11-21
PT98035A (en) 1992-03-31
CN1058212A (en) 1992-01-29
LTIP1713A (en) 1995-08-25
CA2083714A1 (en) 1991-12-21
OA09682A (en) 1993-05-15
CS189491A3 (en) 1992-04-15
BG97200A (en) 1993-12-24
IL98470A0 (en) 1992-07-15
FI925766A (en) 1992-12-18
LT3977B (en) 1996-06-25
HU9204033D0 (en) 1993-03-29
JPH05507713A (en) 1993-11-04
MA22199A1 (en) 1992-04-01
AU8009791A (en) 1992-01-07
CZ279772B6 (en) 1995-06-14
RO110493B1 (en) 1996-01-30
WO1991019711A1 (en) 1991-12-26
NO924775D0 (en) 1992-12-10
LT3952B (en) 1996-05-27
EP0535081A1 (en) 1993-04-07
HUT62881A (en) 1993-06-28
NO924775L (en) 1992-12-10
ZA914297B (en) 1992-03-25
TNSN91049A1 (en) 1992-10-25
AU649453B2 (en) 1994-05-26
AP9100285A0 (en) 1991-07-31
LV10953A (en) 1995-12-20
IS3721A7 (en) 1991-12-21
FI925766A0 (en) 1992-12-18
SE9002206D0 (en) 1990-06-20

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Legal Events

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MM9A Lapsed patents

Effective date: 19961230