PT936217E - Compostos de 1-fenilpirazole e sua utilizacao em medicina - Google Patents

Compostos de 1-fenilpirazole e sua utilizacao em medicina

Info

Publication number
PT936217E
PT936217E PT97909603T PT97909603T PT936217E PT 936217 E PT936217 E PT 936217E PT 97909603 T PT97909603 T PT 97909603T PT 97909603 T PT97909603 T PT 97909603T PT 936217 E PT936217 E PT 936217E
Authority
PT
Portugal
Prior art keywords
compounds
phenylpirazole
medicine
hyperuricacidemia
isobutoxyphenyl
Prior art date
Application number
PT97909603T
Other languages
English (en)
Inventor
Seigo Ishibuchi
Hiroshi Morimoto
Atsushi Fukunari
Hiroyoshi Inoue
Yoichi Naka
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Publication of PT936217E publication Critical patent/PT936217E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
PT97909603T 1996-10-25 1997-10-22 Compostos de 1-fenilpirazole e sua utilizacao em medicina PT936217E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28447996 1996-10-25
JP5578697 1997-03-11
JP26130597 1997-09-26

Publications (1)

Publication Number Publication Date
PT936217E true PT936217E (pt) 2002-05-31

Family

ID=27295710

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97909603T PT936217E (pt) 1996-10-25 1997-10-22 Compostos de 1-fenilpirazole e sua utilizacao em medicina

Country Status (17)

Country Link
US (1) US6015829A (pt)
EP (1) EP0936217B1 (pt)
JP (1) JP3220987B2 (pt)
KR (1) KR100345942B1 (pt)
CN (1) CN1105708C (pt)
AT (1) ATE208379T1 (pt)
AU (1) AU731055B2 (pt)
CA (1) CA2269721C (pt)
DE (1) DE69708142T2 (pt)
DK (1) DK0936217T3 (pt)
ES (1) ES2167720T3 (pt)
HK (1) HK1021982A1 (pt)
ID (1) ID21775A (pt)
IL (1) IL129409A (pt)
PL (1) PL332946A1 (pt)
PT (1) PT936217E (pt)
WO (1) WO1998018765A1 (pt)

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JP5222561B2 (ja) * 2005-10-07 2013-06-26 キッセイ薬品工業株式会社 含窒素芳香族複素環化合物およびそれを含有する医薬組成物
CN101282934A (zh) 2005-10-07 2008-10-08 安斯泰来制药株式会社 三芳基羧酸衍生物
CN101389352B (zh) 2006-02-24 2012-09-19 安斯泰来制药株式会社 治疗或预防消化道溃疡的药物
WO2008010315A1 (fr) * 2006-07-19 2008-01-24 Nippon Medical School Foundation Agent thérapeutique destiné à la sclérose latérale amyotrophique
US20090124623A1 (en) * 2006-11-13 2009-05-14 Christopher Lademacher Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors
KR20090103879A (ko) * 2006-11-13 2009-10-01 다케다 파마슈티칼스 노쓰 어메리카, 인코포레이티드 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법
RU2009131454A (ru) * 2007-01-19 2011-02-27 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы предупреждения или уменьшения числа обострений подагры с применением ингибиторов ксантиноксидоредуктазы и противовоспалительных средств
JP5330990B2 (ja) * 2007-04-11 2013-10-30 キッセイ薬品工業株式会社 含窒素複素環化合物およびそれを含有する医薬組成物
BRPI0810523A2 (pt) * 2007-04-11 2014-10-21 Kissei Pharmaceutical Derivado heterocíclico de 5 membros e uso do mesmo para propósitos médicos.
CA2682391C (en) 2007-04-11 2014-07-08 Kissei Pharmaceutical Co., Ltd. (aza)indole derivative and use thereof for medical purposes
CN101386605B (zh) * 2008-10-23 2010-09-08 中国科学院上海药物研究所 非布司他新型晶体及其制备方法
US20100311756A1 (en) * 2009-01-22 2010-12-09 Takeda Pharmaceuticals North America, Inc. Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof
RU2510393C9 (ru) 2009-02-27 2014-08-27 Тейдзин Фарма Лимитед Способ получения фенилзамещенного гетероциклического производного посредством сочетания с использованием переходного металла в качестве катализатора
CN101580495A (zh) * 2009-05-25 2009-11-18 沈阳药科大学 5-取代苯基-3-异噁唑甲酸及其酯类化合物、组合物及其制备方法
TWI423962B (zh) 2009-10-07 2014-01-21 Lg Life Sciences Ltd 有效作為黃嘌呤氧化酶抑制劑之新穎化合物、其製備方法及含該化合物之醫藥組成物
WO2011103439A1 (en) * 2010-02-19 2011-08-25 Takeda Pharmaceuticals North America, Inc. Methods for stabilizing joint damage in subjects using xanthine oxidoreductase inhibitors
MX353203B (es) 2010-08-27 2018-01-05 Teijin Pharma Ltd Metodo para producir un derivado heterociclico fenilo sustituido por medio del metodo de acoplamiento utilizando un compuesto paladio.
KR101797936B1 (ko) 2010-09-10 2017-11-15 다케다 파마슈티칼스 유에스에이, 인코포레이티드 테오필린과 페북소스타트의 병용 치료 방법
CN102766099B (zh) * 2012-08-07 2015-09-23 沈阳药科大学 具有黄嘌呤氧化酶抑制活性的化合物及其盐、制备方法和用途
CN103848798B (zh) 2012-11-30 2016-01-06 镇江新元素医药科技有限公司 2-芳基硒唑化合物及其药物组合物
MY176149A (en) 2013-03-29 2020-07-24 Teijin Pharma Ltd Pyrazole derivative
CN105294584A (zh) * 2015-11-30 2016-02-03 中国医科大学 1-取代苯基-1h-1,2,3-三唑类化合物、制备方法及其用途
CN106279024B (zh) * 2016-07-19 2018-09-14 华南理工大学 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用
CN106632245B (zh) * 2016-09-30 2019-11-15 华南理工大学 氮取代基苯基吡唑类黄嘌呤氧化还原酶抑制剂及制备与应用
CN108218777A (zh) * 2017-12-13 2018-06-29 华南理工大学 一种硫取代苯基吡唑类xor抑制剂及制备与应用
CN110078668B (zh) * 2019-05-16 2023-03-24 华南理工大学 一种苯基咪唑类xor抑制剂及制备与应用

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Also Published As

Publication number Publication date
ID21775A (id) 1999-07-22
IL129409A (en) 2002-02-10
PL332946A1 (en) 1999-10-25
KR20000052738A (ko) 2000-08-25
AU4723097A (en) 1998-05-22
CA2269721C (en) 2003-04-29
IL129409A0 (en) 2000-02-17
ATE208379T1 (de) 2001-11-15
ES2167720T3 (es) 2002-05-16
DE69708142T2 (de) 2002-07-11
KR100345942B1 (ko) 2002-07-27
JP3220987B2 (ja) 2001-10-22
WO1998018765A1 (fr) 1998-05-07
AU731055B2 (en) 2001-03-22
CN1240432A (zh) 2000-01-05
HK1021982A1 (en) 2000-07-21
EP0936217A4 (en) 2000-01-05
EP0936217A1 (en) 1999-08-18
DK0936217T3 (da) 2002-03-04
CA2269721A1 (en) 1998-05-07
US6015829A (en) 2000-01-18
CN1105708C (zh) 2003-04-16
EP0936217B1 (en) 2001-11-07
DE69708142D1 (de) 2001-12-13

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