GR920100570A - Παραγωγα 3(2η)-πυριδαζινονης και μεθοδος για την παρασκευη τους. - Google Patents

Παραγωγα 3(2η)-πυριδαζινονης και μεθοδος για την παρασκευη τους.

Info

Publication number
GR920100570A
GR920100570A GR920100570A GR920100570A GR920100570A GR 920100570 A GR920100570 A GR 920100570A GR 920100570 A GR920100570 A GR 920100570A GR 920100570 A GR920100570 A GR 920100570A GR 920100570 A GR920100570 A GR 920100570A
Authority
GR
Greece
Prior art keywords
preparation
pyridazinone derivatives
derivatives
diseases
treatment
Prior art date
Application number
GR920100570A
Other languages
English (en)
Other versions
GR1002281B (el
Inventor
Marton Dr Fekete
Laszlo Dr Jaszlits
Maria Kurthy
Luca Levay
Aniko Dr Miklos
Gyorgy Schmidt
Katalin Dr Szemeredi
Erzsebet Dr Zara
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of GR920100570A publication Critical patent/GR920100570A/el
Publication of GR1002281B publication Critical patent/GR1002281B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Abstract

Η εφεύρεση αφορά ρακεμικά ή οπτικώς δραστικά νέα 3 (2Η)-πυριδαζινονοπαράγωγα, μια μέθοδος δια την παρασκευή αυτών,φαρμακευτικές συνθέσεις οι οποίες περιέχουν αυτά και ηχρησιμοποίηση των αναφερθέντων παραγώγων 3 (2Η) -πυριδαζινόνης δια τη θεραπευτική αγωγή ασθενειών και δια τηνπαρασκευή φαρμακευτικών συνθέσεων κατάλληλων δια τηθεραπευτική αγωγή ασθενειών.ω
GR920100570A 1991-12-20 1992-12-21 Παραγωγα 3(2η)-πυριδαζινονης και μεθοδος για την παρασκευη τους. GR1002281B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU914057A HU214320B (hu) 1991-12-20 1991-12-20 Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására

Publications (2)

Publication Number Publication Date
GR920100570A true GR920100570A (el) 1993-08-31
GR1002281B GR1002281B (el) 1996-05-02

Family

ID=10966710

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920100570A GR1002281B (el) 1991-12-20 1992-12-21 Παραγωγα 3(2η)-πυριδαζινονης και μεθοδος για την παρασκευη τους.

Country Status (22)

Country Link
US (1) US5395934A (el)
JP (1) JP3165935B2 (el)
KR (1) KR100234596B1 (el)
CN (1) CN1088578A (el)
AT (1) AT403282B (el)
BE (1) BE1006223A4 (el)
CA (1) CA2085796C (el)
CH (1) CH684754A5 (el)
CZ (1) CZ286039B6 (el)
DE (1) DE4243381B4 (el)
DK (1) DK152892A (el)
ES (1) ES2108595B1 (el)
FI (1) FI106374B (el)
FR (1) FR2685329B1 (el)
GB (1) GB2262526B (el)
GR (1) GR1002281B (el)
HU (1) HU214320B (el)
NL (1) NL194966C (el)
PL (1) PL172933B1 (el)
RU (1) RU2130019C1 (el)
YU (1) YU48973B (el)
ZA (1) ZA929903B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5969017A (en) * 1996-10-31 1999-10-19 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
US5935945A (en) * 1996-10-31 1999-08-10 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
EP1082309B1 (en) * 1998-06-05 2005-09-14 Egis Gyogyszergyar Process for the preparation of a 3(2h)-pyridazinone- 4-substituted amino- 5-chloro- derivative
ES2162731B1 (es) * 1999-06-04 2003-02-16 Faes Fabrica Espanola De Produ Nuevas arilpiperacilnilalquil-3(2h)-piridacinonas.
WO2001034151A1 (en) * 1999-11-11 2001-05-17 Fred Hutchinson Cancer Research Center Novel topoisomerase poisons for the treatment of proliferative disorders
US7173063B1 (en) 2000-11-10 2007-02-06 Fred Hutchinson Cancer Research Center Topoisomerase poisons for the treatment of proliferative disorders
HUP0103064A3 (en) * 2001-07-26 2005-06-28 Egis Gyogyszergyar Nyilvanosan Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it
HU227237B1 (en) * 2001-09-27 2010-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them
WO2003059891A1 (en) * 2002-01-18 2003-07-24 Pharmacia Corporation Substituted pyridazinones as inhibitors of p38
HU227181B1 (en) * 2002-09-11 2010-09-28 Egis Gyogyszergyar Nyilvanosan Use of 5-chloro-4-[3-[n-[2-(3,4-dimethoxyphenyl)ethyl)]-n-methylamino]-propylamino]-3-(2h)-pyridazinone for producing pharmaceutical compositions having metabolic modulator effect
KR101122606B1 (ko) 2009-11-20 2012-03-16 에스케이케미칼주식회사 고나도트로핀 방출 호르몬 수용체 길항제, 이의 제조방법 및 이를 함유하는 약제학적 조성물
JP2013518907A (ja) * 2010-02-08 2013-05-23 アラーガン インコーポレイテッド カンナビノイド−２作動薬として有用なピリダジン誘導体
FR2969606B1 (fr) * 2010-12-22 2013-01-11 Pf Medicament Derives de diarylpyridazinones, leur preparation et leur application en therapeutique humaine
RU2455004C1 (ru) * 2011-04-01 2012-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ФГБОУ ВПО "ЯГТУ") Способ получения сульфохлоридов ряда 6-арилпиридазин-3(2н)-онов

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054946A1 (de) * 1980-12-22 1982-06-30 CASSELLA Aktiengesellschaft Basisch substituierte Pyridazine, ihre Herstellung und ihre Verwendung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1285235A (fr) * 1960-01-21 1962-02-23 Ciba Geigy Procédé de préparation de nouvelles diazines, notamment de 1-aryl-3-r-5-r'pyridazones-(6) dans lesquelles r représente un hydroxyle aliphatiquement éthérifié et r' représente un groupe n-(beta-aryl-éthyl)-pipérazino
US4088764A (en) * 1973-12-27 1978-05-09 Cassella Farbwerke Mainkur Aktiengesellschaft Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
EP0201765B1 (en) * 1985-04-27 1991-09-18 Nissan Chemical Industries Ltd. 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it
US4992433A (en) * 1987-11-23 1991-02-12 Janssen Pharmaceutica N.V. Novel pyridazinamine derivatives
MY104343A (en) * 1987-11-23 1994-03-31 Janssen Pharmaceutica Nv Novel pyridizinamine deravatives
EP0363486A1 (de) * 1988-03-17 1990-04-18 Vsesojuzny Nauchno-Issledovatelsky Inst. Selskokhozyaistv. Biotekh. Vsesojuznoi Ak. Selskokhozyaistv. Nauk Imeni V.I. Lenina Verfahren zur Sterilisation der Staubbeutel von Pflanzen
IE62890B1 (en) * 1988-12-06 1995-03-08 Hafslund Nycomed Pharma New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
DE3902316A1 (de) * 1989-01-26 1990-08-02 Lentia Gmbh Neue piperazinylalkyl-3(2h)-pyridazinone, verfahren zu ihrer herstellung und ihre verwendung als blutdrucksenkende mittel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054946A1 (de) * 1980-12-22 1982-06-30 CASSELLA Aktiengesellschaft Basisch substituierte Pyridazine, ihre Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
PL297070A1 (en) 1994-03-07
NL9202210A (nl) 1993-07-16
DK152892D0 (da) 1992-12-21
JP3165935B2 (ja) 2001-05-14
DE4243381B4 (de) 2005-07-28
NL194966C (nl) 2003-09-02
FI925807A (fi) 1993-06-21
CN1088578A (zh) 1994-06-29
US5395934A (en) 1995-03-07
HUT62865A (en) 1993-06-28
ZA929903B (en) 1993-06-24
ES2108595B1 (es) 1998-08-16
CH684754A5 (de) 1994-12-15
AT403282B (de) 1997-12-29
AU3031792A (en) 1993-06-24
AU652304B2 (en) 1994-08-18
JPH05255276A (ja) 1993-10-05
HU914057D0 (en) 1992-03-30
YU109292A (sr) 1996-01-09
FR2685329B1 (fr) 1994-12-02
KR100234596B1 (ko) 1999-12-15
BE1006223A4 (fr) 1994-06-14
FI925807A0 (fi) 1992-12-21
ATA253592A (de) 1997-05-15
CZ286039B6 (cs) 1999-12-15
FI106374B (fi) 2001-01-31
NL194966B (nl) 2003-05-01
GB9226601D0 (en) 1993-02-17
GR1002281B (el) 1996-05-02
GB2262526B (en) 1995-07-26
DK152892A (da) 1993-06-21
HU214320B (hu) 1998-03-02
CA2085796C (en) 2000-08-08
FR2685329A1 (fr) 1993-06-25
DE4243381A1 (el) 1993-06-24
PL172933B1 (pl) 1997-12-31
CA2085796A1 (en) 1993-06-21
GB2262526A (en) 1993-06-23
RU2130019C1 (ru) 1999-05-10
CZ380992A3 (en) 1993-09-15
ES2108595A1 (es) 1997-12-16
YU48973B (sh) 2003-02-28

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