FI925807A0 - Foerfarande foer framstaellning av terapeutiskt anvaendbara 3(2h)-pyridazinonderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 3(2h)-pyridazinonderivat

Info

Publication number
FI925807A0
FI925807A0 FI925807A FI925807A FI925807A0 FI 925807 A0 FI925807 A0 FI 925807A0 FI 925807 A FI925807 A FI 925807A FI 925807 A FI925807 A FI 925807A FI 925807 A0 FI925807 A0 FI 925807A0
Authority
FI
Finland
Prior art keywords
pyridazinonderivat
analyzer
therapeutic
preparation
frame
Prior art date
Application number
FI925807A
Other languages
English (en)
Other versions
FI106374B (fi
FI925807A (fi
Inventor
Peter Matyus
Klara Czako
Ildiko Varga
Andrea Jednakovics
Agnes Papp
Ilona Bodi
Gyoergy Rabloczky
Andras Varro
Laszlo Jaszlits
Aniko Miklos
Luca Levay
Gyoergy Schmidt
Marton Fekete
Maria Kuerthy
Katalin Szemeredi
Erzsebet Zara
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FI925807A0 publication Critical patent/FI925807A0/fi
Publication of FI925807A publication Critical patent/FI925807A/fi
Application granted granted Critical
Publication of FI106374B publication Critical patent/FI106374B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI925807A 1991-12-20 1992-12-21 Menetelmä terapeuttisesti käyttökelpoisten 3(2H)-pyridatsinonijohdannaisten valmistamiseksi FI106374B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU405791 1991-12-20
HU914057A HU214320B (hu) 1991-12-20 1991-12-20 Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására

Publications (3)

Publication Number Publication Date
FI925807A0 true FI925807A0 (fi) 1992-12-21
FI925807A FI925807A (fi) 1993-06-21
FI106374B FI106374B (fi) 2001-01-31

Family

ID=10966710

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925807A FI106374B (fi) 1991-12-20 1992-12-21 Menetelmä terapeuttisesti käyttökelpoisten 3(2H)-pyridatsinonijohdannaisten valmistamiseksi

Country Status (22)

Country Link
US (1) US5395934A (fi)
JP (1) JP3165935B2 (fi)
KR (1) KR100234596B1 (fi)
CN (1) CN1088578A (fi)
AT (1) AT403282B (fi)
BE (1) BE1006223A4 (fi)
CA (1) CA2085796C (fi)
CH (1) CH684754A5 (fi)
CZ (1) CZ286039B6 (fi)
DE (1) DE4243381B4 (fi)
DK (1) DK152892A (fi)
ES (1) ES2108595B1 (fi)
FI (1) FI106374B (fi)
FR (1) FR2685329B1 (fi)
GB (1) GB2262526B (fi)
GR (1) GR1002281B (fi)
HU (1) HU214320B (fi)
NL (1) NL194966C (fi)
PL (1) PL172933B1 (fi)
RU (1) RU2130019C1 (fi)
YU (1) YU48973B (fi)
ZA (1) ZA929903B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935945A (en) * 1996-10-31 1999-08-10 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
US5969017A (en) * 1996-10-31 1999-10-19 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
BR9815967A (pt) 1998-06-05 2004-06-22 Egyt Gyogyszervegyeszeti Gyar Processo para a preparação de um derivado de amino-5-cloro de 3(2h)-piridazinona-4-substituìdo
ES2162731B1 (es) * 1999-06-04 2003-02-16 Faes Fabrica Espanola De Produ Nuevas arilpiperacilnilalquil-3(2h)-piridacinonas.
AU1592301A (en) * 1999-11-11 2001-06-06 Fred Hutchinson Cancer Research Center Novel topoisomerase poisons for the treatment of proliferative disorders
US7173063B1 (en) 2000-11-10 2007-02-06 Fred Hutchinson Cancer Research Center Topoisomerase poisons for the treatment of proliferative disorders
HUP0103064A3 (en) * 2001-07-26 2005-06-28 Egis Gyogyszergyar Nyilvanosan Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it
HU227237B1 (en) * 2001-09-27 2010-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them
JP2005519895A (ja) * 2002-01-18 2005-07-07 ファルマシア・コーポレーション P38阻害剤としての置換ピリダジノン
HU227181B1 (en) * 2002-09-11 2010-09-28 Egis Gyogyszergyar Nyilvanosan Use of 5-chloro-4-[3-[n-[2-(3,4-dimethoxyphenyl)ethyl)]-n-methylamino]-propylamino]-3-(2h)-pyridazinone for producing pharmaceutical compositions having metabolic modulator effect
KR101122606B1 (ko) * 2009-11-20 2012-03-16 에스케이케미칼주식회사 고나도트로핀 방출 호르몬 수용체 길항제, 이의 제조방법 및 이를 함유하는 약제학적 조성물
BR112012019920A2 (pt) * 2010-02-08 2016-04-26 Allergan Inc derivados de piridazina úteis como agonístas de canabinoide-2.
FR2969606B1 (fr) * 2010-12-22 2013-01-11 Pf Medicament Derives de diarylpyridazinones, leur preparation et leur application en therapeutique humaine
RU2455004C1 (ru) * 2011-04-01 2012-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ФГБОУ ВПО "ЯГТУ") Способ получения сульфохлоридов ряда 6-арилпиридазин-3(2н)-онов

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1285235A (fr) * 1960-01-21 1962-02-23 Ciba Geigy Procédé de préparation de nouvelles diazines, notamment de 1-aryl-3-r-5-r'pyridazones-(6) dans lesquelles r représente un hydroxyle aliphatiquement éthérifié et r' représente un groupe n-(beta-aryl-éthyl)-pipérazino
US4088764A (en) * 1973-12-27 1978-05-09 Cassella Farbwerke Mainkur Aktiengesellschaft Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol
DE3048487A1 (de) * 1980-12-22 1982-07-29 Cassella Ag, 6000 Frankfurt Basisch substituierte pyridazine, ihre herstellung und ihre verwendung
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
US4892947A (en) * 1985-04-27 1990-01-09 Nissan Chemical Industries Ltd. 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it
MY104343A (en) * 1987-11-23 1994-03-31 Janssen Pharmaceutica Nv Novel pyridizinamine deravatives
US4992433A (en) * 1987-11-23 1991-02-12 Janssen Pharmaceutica N.V. Novel pyridazinamine derivatives
JPH02503673A (ja) * 1988-03-17 1990-11-01 フセソユズニ ナウチノ―イススレドバテルスキ インスティテュト セルスコホズヤイストベンノイ ビオテフノロギイ フセソユズノイ アカデミイ セルスコホズヤイストベンニフ ナウク イメニ ベー.イー.レニナ 葯の不稔性化方法
IE62890B1 (en) * 1988-12-06 1995-03-08 Hafslund Nycomed Pharma New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
DE3902316A1 (de) * 1989-01-26 1990-08-02 Lentia Gmbh Neue piperazinylalkyl-3(2h)-pyridazinone, verfahren zu ihrer herstellung und ihre verwendung als blutdrucksenkende mittel

Also Published As

Publication number Publication date
ATA253592A (de) 1997-05-15
GR1002281B (el) 1996-05-02
JPH05255276A (ja) 1993-10-05
GB2262526B (en) 1995-07-26
CN1088578A (zh) 1994-06-29
FR2685329A1 (fr) 1993-06-25
DE4243381A1 (fi) 1993-06-24
AU652304B2 (en) 1994-08-18
BE1006223A4 (fr) 1994-06-14
DK152892D0 (da) 1992-12-21
US5395934A (en) 1995-03-07
AT403282B (de) 1997-12-29
CH684754A5 (de) 1994-12-15
RU2130019C1 (ru) 1999-05-10
DK152892A (da) 1993-06-21
AU3031792A (en) 1993-06-24
GB9226601D0 (en) 1993-02-17
KR100234596B1 (ko) 1999-12-15
HU914057D0 (en) 1992-03-30
GB2262526A (en) 1993-06-23
PL297070A1 (en) 1994-03-07
NL194966B (nl) 2003-05-01
CA2085796C (en) 2000-08-08
JP3165935B2 (ja) 2001-05-14
FI106374B (fi) 2001-01-31
NL194966C (nl) 2003-09-02
CZ380992A3 (en) 1993-09-15
CA2085796A1 (en) 1993-06-21
ES2108595A1 (es) 1997-12-16
NL9202210A (nl) 1993-07-16
DE4243381B4 (de) 2005-07-28
GR920100570A (el) 1993-08-31
FI925807A (fi) 1993-06-21
YU109292A (sr) 1996-01-09
YU48973B (sh) 2003-02-28
HUT62865A (en) 1993-06-28
ZA929903B (en) 1993-06-24
PL172933B1 (pl) 1997-12-31
ES2108595B1 (es) 1998-08-16
FR2685329B1 (fr) 1994-12-02
CZ286039B6 (cs) 1999-12-15
HU214320B (hu) 1998-03-02

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MA Patent expired