NO178826C - Fremgangsmåte til fremstilling av 4'-demetylepipodofyllotoksin-glukosid-4'-fosfater - Google Patents

Fremgangsmåte til fremstilling av 4'-demetylepipodofyllotoksin-glukosid-4'-fosfater

Info

Publication number
NO178826C
NO178826C NO921363A NO921363A NO178826C NO 178826 C NO178826 C NO 178826C NO 921363 A NO921363 A NO 921363A NO 921363 A NO921363 A NO 921363A NO 178826 C NO178826 C NO 178826C
Authority
NO
Norway
Prior art keywords
demethylpipodophyllotoxin
glucoside
phosphates
preparation
Prior art date
Application number
NO921363A
Other languages
English (en)
Other versions
NO178826B (no
NO921363L (no
NO921363D0 (no
Inventor
Mark G Saulnier
John F Kadow
David R Langley
Min Min Tun
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO921363D0 publication Critical patent/NO921363D0/no
Publication of NO921363L publication Critical patent/NO921363L/no
Priority to NO954533A priority Critical patent/NO954533D0/no
Publication of NO178826B publication Critical patent/NO178826B/no
Publication of NO178826C publication Critical patent/NO178826C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO921363A 1991-04-29 1992-04-08 Fremgangsmåte til fremstilling av 4'-demetylepipodofyllotoksin-glukosid-4'-fosfater NO178826C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO954533A NO954533D0 (no) 1991-04-29 1995-11-10 Fremgangsmåte til fremstilling av et beskyttet 4'-demetylepipodofyllotoksinglukosid-4'-fosfat

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69398191A 1991-04-29 1991-04-29
US83495492A 1992-02-20 1992-02-20

Publications (4)

Publication Number Publication Date
NO921363D0 NO921363D0 (no) 1992-04-08
NO921363L NO921363L (no) 1992-10-30
NO178826B NO178826B (no) 1996-03-04
NO178826C true NO178826C (no) 1996-06-12

Family

ID=27105281

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921363A NO178826C (no) 1991-04-29 1992-04-08 Fremgangsmåte til fremstilling av 4'-demetylepipodofyllotoksin-glukosid-4'-fosfater

Country Status (16)

Country Link
EP (1) EP0511563A1 (no)
JP (1) JPH05178880A (no)
KR (1) KR920019812A (no)
CN (1) CN1030141C (no)
AU (2) AU653788B2 (no)
CA (1) CA2062510A1 (no)
CZ (1) CZ131092A3 (no)
FI (1) FI921756A (no)
HU (3) HUT65255A (no)
IE (1) IE921285A1 (no)
IL (1) IL101188A (no)
MY (1) MY131083A (no)
NO (1) NO178826C (no)
NZ (1) NZ242059A (no)
SK (1) SK131092A3 (no)
TW (1) TW260671B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3061476B2 (ja) * 1992-04-24 2000-07-10 日本化薬株式会社 エトポシド燐酸エステルの製造法
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフィロトキシン誘導体
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
DE3913326A1 (de) * 1989-04-22 1990-11-08 Behringwerke Ag Verfahren zur herstellung von etoposiden
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5034380A (en) * 1989-11-20 1991-07-23 Bristol-Myers Squibb Company Alkoxymethylidene epipodophyllotoxin glucosides

Also Published As

Publication number Publication date
AU6898194A (en) 1994-10-06
KR920019812A (ko) 1992-11-20
IL101188A (en) 1995-12-08
TW260671B (no) 1995-10-21
IL101188A0 (en) 1992-11-15
HU9300731D0 (en) 1993-05-28
FI921756A0 (fi) 1992-04-21
HUT63428A (en) 1993-08-30
JPH05178880A (ja) 1993-07-20
SK131092A3 (en) 1995-09-13
NO178826B (no) 1996-03-04
FI921756A (fi) 1992-10-30
CZ131092A3 (en) 1993-01-13
HU9300730D0 (en) 1993-05-28
CN1066268A (zh) 1992-11-18
AU1288692A (en) 1992-11-05
CA2062510A1 (en) 1992-10-30
NZ242059A (en) 1994-07-26
CN1030141C (zh) 1995-10-25
HU9201341D0 (en) 1992-07-28
AU658343B2 (en) 1995-04-06
EP0511563A1 (en) 1992-11-04
IE921285A1 (en) 1992-11-04
MY131083A (en) 2007-07-31
HUT63431A (en) 1993-08-30
NO921363L (no) 1992-10-30
NO921363D0 (no) 1992-04-08
HUT65255A (en) 1994-05-02
AU653788B2 (en) 1994-10-13

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