HUT63428A - Process for producing protected4'-demethyl epipodophyllotoxin-4'-phosphates - Google Patents

Process for producing protected4'-demethyl epipodophyllotoxin-4'-phosphates

Info

Publication number
HUT63428A
HUT63428A HU939300731A HU9300731A HUT63428A HU T63428 A HUT63428 A HU T63428A HU 939300731 A HU939300731 A HU 939300731A HU 9300731 A HU9300731 A HU 9300731A HU T63428 A HUT63428 A HU T63428A
Authority
HU
Hungary
Prior art keywords
protected4
phosphates
producing
demethyl epipodophyllotoxin
epipodophyllotoxin
Prior art date
Application number
HU939300731A
Other languages
English (en)
Other versions
HU9300731D0 (en
Inventor
Mark G Saulnier
John F Kadow
David R Langley
Min Min Tun
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HU9300731D0 publication Critical patent/HU9300731D0/hu
Publication of HUT63428A publication Critical patent/HUT63428A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
HU939300731A 1991-04-29 1992-04-22 Process for producing protected4'-demethyl epipodophyllotoxin-4'-phosphates HUT63428A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69398191A 1991-04-29 1991-04-29
US83495492A 1992-02-20 1992-02-20

Publications (2)

Publication Number Publication Date
HU9300731D0 HU9300731D0 (en) 1993-05-28
HUT63428A true HUT63428A (en) 1993-08-30

Family

ID=27105281

Family Applications (3)

Application Number Title Priority Date Filing Date
HU9300730A HUT63431A (en) 1991-04-29 1992-04-22 Process for producing protected 4'-demethyl epipodophyllotoxin-glycoside-4'-phosphates
HU939300731A HUT63428A (en) 1991-04-29 1992-04-22 Process for producing protected4'-demethyl epipodophyllotoxin-4'-phosphates
HU9201341A HUT65255A (en) 1991-04-29 1992-04-22 Process for preparing 4'-demethyl-epipodophyllotoxin-glucoside 4'-phosphates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU9300730A HUT63431A (en) 1991-04-29 1992-04-22 Process for producing protected 4'-demethyl epipodophyllotoxin-glycoside-4'-phosphates

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9201341A HUT65255A (en) 1991-04-29 1992-04-22 Process for preparing 4'-demethyl-epipodophyllotoxin-glucoside 4'-phosphates

Country Status (16)

Country Link
EP (1) EP0511563A1 (hu)
JP (1) JPH05178880A (hu)
KR (1) KR920019812A (hu)
CN (1) CN1030141C (hu)
AU (2) AU653788B2 (hu)
CA (1) CA2062510A1 (hu)
CZ (1) CZ131092A3 (hu)
FI (1) FI921756A (hu)
HU (3) HUT63431A (hu)
IE (1) IE921285A1 (hu)
IL (1) IL101188A (hu)
MY (1) MY131083A (hu)
NO (1) NO178826C (hu)
NZ (1) NZ242059A (hu)
SK (1) SK131092A3 (hu)
TW (1) TW260671B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3061476B2 (ja) * 1992-04-24 2000-07-10 日本化薬株式会社 エトポシド燐酸エステルの製造法
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフィロトキシン誘導体
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
DE3913326A1 (de) * 1989-04-22 1990-11-08 Behringwerke Ag Verfahren zur herstellung von etoposiden
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5034380A (en) * 1989-11-20 1991-07-23 Bristol-Myers Squibb Company Alkoxymethylidene epipodophyllotoxin glucosides

Also Published As

Publication number Publication date
EP0511563A1 (en) 1992-11-04
CN1066268A (zh) 1992-11-18
HUT63431A (en) 1993-08-30
IL101188A (en) 1995-12-08
MY131083A (en) 2007-07-31
NO921363D0 (no) 1992-04-08
FI921756A (fi) 1992-10-30
AU1288692A (en) 1992-11-05
KR920019812A (ko) 1992-11-20
AU658343B2 (en) 1995-04-06
NO178826B (no) 1996-03-04
NZ242059A (en) 1994-07-26
CZ131092A3 (en) 1993-01-13
HU9300730D0 (en) 1993-05-28
AU6898194A (en) 1994-10-06
TW260671B (hu) 1995-10-21
CA2062510A1 (en) 1992-10-30
NO178826C (no) 1996-06-12
JPH05178880A (ja) 1993-07-20
AU653788B2 (en) 1994-10-13
IE921285A1 (en) 1992-11-04
HU9201341D0 (en) 1992-07-28
IL101188A0 (en) 1992-11-15
CN1030141C (zh) 1995-10-25
HUT65255A (en) 1994-05-02
NO921363L (no) 1992-10-30
SK131092A3 (en) 1995-09-13
FI921756A0 (fi) 1992-04-21
HU9300731D0 (en) 1993-05-28

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal