PT93527A - Processo para a preparacao de derivados de xantina - Google Patents

Processo para a preparacao de derivados de xantina

Info

Publication number
PT93527A
PT93527A PT93527A PT9352790A PT93527A PT 93527 A PT93527 A PT 93527A PT 93527 A PT93527 A PT 93527A PT 9352790 A PT9352790 A PT 9352790A PT 93527 A PT93527 A PT 93527A
Authority
PT
Portugal
Prior art keywords
formula
disorders
group
alkyl
preparation
Prior art date
Application number
PT93527A
Other languages
English (en)
Other versions
PT93527B (pt
Inventor
Harald Maschler
Barbara Ann Spicer
Harry Smith
Original Assignee
Beecham Group Plc
Beecham Wuelfing Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc, Beecham Wuelfing Gmbh & Co Kg filed Critical Beecham Group Plc
Publication of PT93527A publication Critical patent/PT93527A/pt
Publication of PT93527B publication Critical patent/PT93527B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT93527A 1989-03-23 1990-03-21 Processo para a preparacao de derivados de xantina PT93527B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906792A GB8906792D0 (en) 1989-03-23 1989-03-23 Treatment and compounds

Publications (2)

Publication Number Publication Date
PT93527A true PT93527A (pt) 1990-11-07
PT93527B PT93527B (pt) 1996-08-30

Family

ID=10653940

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93527A PT93527B (pt) 1989-03-23 1990-03-21 Processo para a preparacao de derivados de xantina

Country Status (27)

Country Link
US (4) US5981535A (pt)
EP (2) EP1120417A3 (pt)
JP (1) JP2510889B2 (pt)
KR (1) KR0160768B1 (pt)
CN (1) CN1031641C (pt)
AT (1) ATE213498T1 (pt)
AU (1) AU629315B2 (pt)
CA (1) CA2012686C (pt)
CZ (1) CZ391891A3 (pt)
DE (1) DE69033915T2 (pt)
DK (1) DK0389282T3 (pt)
ES (1) ES2173074T3 (pt)
FI (1) FI95033C (pt)
GB (1) GB8906792D0 (pt)
HK (1) HK1040392A1 (pt)
HU (1) HU207081B (pt)
IL (1) IL93832A (pt)
MA (1) MA21800A1 (pt)
MY (1) MY109737A (pt)
NO (1) NO175592C (pt)
NZ (1) NZ233021A (pt)
PL (1) PL164811B1 (pt)
PT (1) PT93527B (pt)
SA (1) SA90100215B1 (pt)
SK (1) SK391891A3 (pt)
ZA (1) ZA902170B (pt)
ZW (1) ZW3690A1 (pt)

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Also Published As

Publication number Publication date
EP1120417A3 (en) 2001-08-08
JPH02273676A (ja) 1990-11-08
MA21800A1 (fr) 1990-12-31
EP0389282B1 (en) 2002-02-20
KR0160768B1 (ko) 1998-12-01
CN1031641C (zh) 1996-04-24
AU5208390A (en) 1990-09-27
DE69033915T2 (de) 2002-10-10
CA2012686C (en) 1999-12-07
FI901447A0 (fi) 1990-03-22
IL93832A0 (en) 1990-12-23
ATE213498T1 (de) 2002-03-15
ZW3690A1 (en) 1991-02-06
GB8906792D0 (en) 1989-05-10
SK391891A3 (en) 2000-12-11
ES2173074T3 (es) 2002-10-16
HK1040392A1 (zh) 2002-06-07
CZ391891A3 (en) 1993-11-17
NO175592C (no) 1994-11-02
US5734051A (en) 1998-03-31
EP1120417A2 (en) 2001-08-01
CA2012686A1 (en) 1990-09-23
KR900013962A (ko) 1990-10-22
PT93527B (pt) 1996-08-30
US6531600B1 (en) 2003-03-11
NO901300L (no) 1990-09-24
NO175592B (no) 1994-07-25
FI95033B (fi) 1995-08-31
DE69033915D1 (de) 2002-03-28
CN1047502A (zh) 1990-12-05
JP2510889B2 (ja) 1996-06-26
EP0389282A3 (en) 1992-07-01
NO901300D0 (no) 1990-03-21
AU629315B2 (en) 1992-10-01
SA90100215B1 (ar) 2001-10-07
HU901792D0 (en) 1990-06-28
US5981535A (en) 1999-11-09
US6180791B1 (en) 2001-01-30
EP0389282A2 (en) 1990-09-26
NZ233021A (en) 1993-12-23
IL93832A (en) 1994-07-31
DK0389282T3 (da) 2002-06-03
HUT54155A (en) 1991-01-28
ZA902170B (en) 1991-03-27
FI95033C (fi) 1995-12-11
PL164811B1 (pl) 1994-10-31
HU207081B (en) 1993-03-01
MY109737A (en) 1997-05-31

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