PT93424B - Processo para a preparacao de uma composicao contendo d-cicloserina e d- -alanina para melhoria de memoria e de aprendizagem ou para tratamento de doencas psicoticas ou cognitivas - Google Patents

Processo para a preparacao de uma composicao contendo d-cicloserina e d- -alanina para melhoria de memoria e de aprendizagem ou para tratamento de doencas psicoticas ou cognitivas Download PDF

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Publication number
PT93424B
PT93424B PT93424A PT9342490A PT93424B PT 93424 B PT93424 B PT 93424B PT 93424 A PT93424 A PT 93424A PT 9342490 A PT9342490 A PT 9342490A PT 93424 B PT93424 B PT 93424B
Authority
PT
Portugal
Prior art keywords
cycloserine
therapeutically effective
alanine
effective amount
treatment
Prior art date
Application number
PT93424A
Other languages
English (en)
Portuguese (pt)
Other versions
PT93424A (pt
Inventor
Alexis A Cordi
Michael R Jans
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT93424A publication Critical patent/PT93424A/pt
Publication of PT93424B publication Critical patent/PT93424B/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
PT93424A 1989-03-15 1990-03-14 Processo para a preparacao de uma composicao contendo d-cicloserina e d- -alanina para melhoria de memoria e de aprendizagem ou para tratamento de doencas psicoticas ou cognitivas PT93424B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32427989A 1989-03-15 1989-03-15
US07/473,241 US5061721A (en) 1989-03-15 1990-02-06 Composition containing d-cycloserine and d-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder

Publications (2)

Publication Number Publication Date
PT93424A PT93424A (pt) 1990-11-07
PT93424B true PT93424B (pt) 1996-08-30

Family

ID=26984373

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93424A PT93424B (pt) 1989-03-15 1990-03-14 Processo para a preparacao de uma composicao contendo d-cicloserina e d- -alanina para melhoria de memoria e de aprendizagem ou para tratamento de doencas psicoticas ou cognitivas

Country Status (17)

Country Link
US (1) US5061721A (Direct)
EP (1) EP0387867B1 (Direct)
JP (1) JP2963720B2 (Direct)
KR (1) KR900013961A (Direct)
AT (1) ATE88890T1 (Direct)
AU (1) AU624917B2 (Direct)
CA (1) CA2010635C (Direct)
DE (1) DE69001503T2 (Direct)
DK (1) DK0387867T3 (Direct)
ES (1) ES2055197T3 (Direct)
FI (1) FI901289A7 (Direct)
GR (1) GR3008225T3 (Direct)
IE (1) IE64130B1 (Direct)
IL (1) IL93562A (Direct)
NO (1) NO901198L (Direct)
NZ (1) NZ232809A (Direct)
PT (1) PT93424B (Direct)

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US5302609A (en) * 1992-12-16 1994-04-12 The Regents Of The University Of Michigan Treatment of diabetic nephropathy
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US20040208875A1 (en) 1995-03-15 2004-10-21 Queen's University At Kingston Method for treating amyloidosis
US5523323A (en) * 1993-09-14 1996-06-04 Maccecchini; Maria-Luisa Use of partial agonists of the NMDA receptor to reduce opiate induced tolerance and dependence
WO1996015788A1 (en) * 1994-11-23 1996-05-30 G.D. Searle & Co. Use of amino-isoxazolidone compounds for improvement of implicit memory
JPH11501619A (ja) * 1995-02-15 1999-02-09 ベアーズデン バイオ，インコーポレイテッド アルキルカルボキシアミノ酸−カイネートレセプターのモジュレーター
EP0964691A4 (en) 1996-07-22 2002-10-30 Cognetix Inc USE OF CONANTOKINE
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US6277825B1 (en) 1996-07-22 2001-08-21 University Of Utah Research Foundation Use of conantokins for treating pain
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US6551993B1 (en) * 1999-08-16 2003-04-22 Thomas Jefferson University Partial agonists at the glycine modulatory site of the NMDA receptor for treating cognitive dysfunction
US6399574B1 (en) 2000-03-22 2002-06-04 University Of Utah Research Foundation Use of conantokins
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
US20050096396A1 (en) * 2002-03-28 2005-05-05 Emory University Acute pharmacologic augmentation of psychotherapy with enhancers of learning or conditioning
US7846913B2 (en) 2003-12-29 2010-12-07 Mcdevitt Jason Patrick Compositions and methods to treat recurrent medical conditions
AU2002311784B2 (en) * 2001-03-29 2007-11-22 Michael Davis Acute pharmacologic augmentation of psychotherapy with enhancers of learning or conditioning
CN1527813A (zh) 2001-04-02 2004-09-08 О 作为治疗剂的抗氧化剂硝基氧和亚硝氮碳基
DE60229371D1 (de) * 2001-05-02 2008-11-27 Brni Neurosciences Inst Kohlensäureanhydrase-aktivatoren zur verbesserung der lern- und gedächtnisleistung
AU2003215522A1 (en) * 2002-03-15 2003-09-29 H. Lundbeck A/S Use of asc-1 inhibitors to treat neurological and psychiatric disorders
US20050014743A1 (en) * 2003-05-27 2005-01-20 Forest Laboratories, Inc. Combination of an NMDA receptor antagonist and a selective serotonin reuptake inhibitor for the treatment of depression and other mood disorders
US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
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TW200716088A (en) 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
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US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
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KR101692275B1 (ko) 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 ２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도
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CN109661398B (zh) 2016-08-01 2022-07-05 阿普廷伊克斯股份有限公司 螺-内酰胺和二-螺-内酰胺nmda受体调节剂及其用途
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Also Published As

Publication number Publication date
EP0387867A1 (en) 1990-09-19
IL93562A0 (en) 1990-11-29
DE69001503T2 (de) 1993-09-09
EP0387867B1 (en) 1993-05-05
AU624917B2 (en) 1992-06-25
KR900013961A (ko) 1990-10-22
IL93562A (en) 1996-01-31
AU5073490A (en) 1990-09-20
CA2010635C (en) 2001-03-06
CA2010635A1 (en) 1990-09-15
DK0387867T3 (da) 1993-06-01
NO901198D0 (no) 1990-03-14
GR3008225T3 (Direct) 1993-09-30
FI901289A0 (fi) 1990-03-15
JP2963720B2 (ja) 1999-10-18
US5061721A (en) 1991-10-29
NO901198L (no) 1990-09-17
DE69001503D1 (de) 1993-06-09
NZ232809A (en) 1992-05-26
IE64130B1 (en) 1995-07-12
PT93424A (pt) 1990-11-07
IE900921L (en) 1990-09-15
ES2055197T3 (es) 1994-08-16
ATE88890T1 (de) 1993-05-15
FI901289A7 (fi) 1990-09-16
JPH03148221A (ja) 1991-06-25

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FG3A Patent granted, date of granting

Effective date: 19960502

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19971130