PT923568E - Novas benzofuran-4-carboxamidas - Google Patents

Novas benzofuran-4-carboxamidas

Info

Publication number
PT923568E
PT923568E PT97942858T PT97942858T PT923568E PT 923568 E PT923568 E PT 923568E PT 97942858 T PT97942858 T PT 97942858T PT 97942858 T PT97942858 T PT 97942858T PT 923568 E PT923568 E PT 923568E
Authority
PT
Portugal
Prior art keywords
carboxamides
new benzofuran
benzofuran
new
substituted
Prior art date
Application number
PT97942858T
Other languages
English (en)
Portuguese (pt)
Inventor
Hans-Peter Kley
Christian Schudt
Rolf Beume
Dietrich Hafner
Ulrich Thibaut
Wolf-Rudiger Ulrich
Dieter Flockerzi
Beate Schmidt
Armin Hatzelmann
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT923568E publication Critical patent/PT923568E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Table Devices Or Equipment (AREA)
PT97942858T 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas PT923568E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19

Publications (1)

Publication Number Publication Date
PT923568E true PT923568E (pt) 2003-04-30

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97942858T PT923568E (pt) 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas

Country Status (11)

Country Link
US (1) US6211203B1 (en:Method)
EP (1) EP0923568B9 (en:Method)
JP (1) JP4309475B2 (en:Method)
AT (1) ATE229516T1 (en:Method)
AU (1) AU4454597A (en:Method)
CY (1) CY2458B1 (en:Method)
DE (1) DE69717827T2 (en:Method)
DK (1) DK0923568T5 (en:Method)
ES (1) ES2188983T4 (en:Method)
PT (1) PT923568E (en:Method)
WO (1) WO1998007715A1 (en:Method)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL329912A1 (en) * 1996-05-20 1999-04-26 Darwin Discovery Ltd Benzofurane carboxyamides and their therapeutic applications
CN1290266A (zh) * 1998-02-09 2001-04-04 达尔文发现有限公司 苯并呋喃－4－甲酰胺和其治疗用途
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
DE59906365D1 (de) * 1998-06-10 2003-08-28 Altana Pharma Ag Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
CA2345459A1 (en) * 1998-11-12 2000-05-18 Regine Bohacek Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
SK287231B6 (sk) 1999-08-21 2010-04-07 Nycomed Gmbh Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
AU2004226353A1 (en) 2003-04-01 2004-10-14 Laboratoires Serono Sa Inhibitors of phosphodiesterases in infertility
EP2275096A3 (en) 2005-08-26 2011-07-13 Braincells, Inc. Neurogenesis via modulation of the muscarinic receptors
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス，インコーポレイティド 神経発生のｇａｂａ受容体媒介調節
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
EP2344458A1 (en) 2008-09-11 2011-07-20 Pfizer Inc. Heteroaryls amide derivatives and their use as glucokinase activators
AR074760A1 (es) 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
DK2406253T3 (da) * 2009-03-11 2013-08-12 Pfizer Benzofuranylderivater anvendt som glucokinase-inhibitorer
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
JP5746334B2 (ja) * 2010-06-16 2015-07-08 シマベイ セラピューティクス， インコーポレーテッド Ｇｐｒ１２０受容体作動薬及びその使用
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
US11390614B2 (en) 2017-11-10 2022-07-19 Jiangsu Hengrui Medicine Co., Ltd. Method for preparing benzofuran derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2137754C1 (ru) * 1993-07-02 1999-09-20 Бик Гульден Ломберг Хемише Фабрик ГмбХ Фторалкоксизамещенные бензамиды, способ их получения и фармацевтическая композиция на их основе
AU702346B2 (en) * 1994-07-22 1999-02-18 Altana Pharma Ag Dihydrobenzofuranes
AU705690B2 (en) * 1995-05-19 1999-05-27 Kyowa Hakko Kogyo Co. Ltd. Oxygen-containing heterocyclic compounds
ATE215540T1 (de) * 1995-12-05 2002-04-15 Darwin Discovery Ltd Benzofuran-carboxamide und -sulfonamide
PL329912A1 (en) * 1996-05-20 1999-04-26 Darwin Discovery Ltd Benzofurane carboxyamides and their therapeutic applications

Also Published As

Publication number Publication date
DK0923568T3 (da) 2003-04-07
JP4309475B2 (ja) 2009-08-05
ATE229516T1 (de) 2002-12-15
CY2458B1 (en) 2005-06-03
EP0923568A1 (en) 1999-06-23
DK0923568T5 (da) 2003-11-03
AU4454597A (en) 1998-03-06
EP0923568B1 (en) 2002-12-11
US6211203B1 (en) 2001-04-03
ES2188983T4 (es) 2004-06-01
ES2188983T3 (es) 2003-07-01
DE69717827D1 (de) 2003-01-23
EP0923568B9 (en) 2003-08-13
DE69717827T2 (de) 2003-09-04
WO1998007715A9 (en) 1999-04-29
JP2000516932A (ja) 2000-12-19
WO1998007715A1 (en) 1998-02-26

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