PT86115B - Processo de preparacao de 7(4h)-tieno{3,2-b}-piridinonas - Google Patents

Processo de preparacao de 7(4h)-tieno{3,2-b}-piridinonas Download PDF

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Publication number
PT86115B
PT86115B PT86115A PT8611587A PT86115B PT 86115 B PT86115 B PT 86115B PT 86115 A PT86115 A PT 86115A PT 8611587 A PT8611587 A PT 8611587A PT 86115 B PT86115 B PT 86115B
Authority
PT
Portugal
Prior art keywords
formula
compounds
mixture
prepared
lower alkyl
Prior art date
Application number
PT86115A
Other languages
English (en)
Portuguese (pt)
Other versions
PT86115A (en
Inventor
Roy Victor Davies
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of PT86115A publication Critical patent/PT86115A/pt
Publication of PT86115B publication Critical patent/PT86115B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PT86115A 1986-11-20 1987-11-11 Processo de preparacao de 7(4h)-tieno{3,2-b}-piridinonas PT86115B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868627698A GB8627698D0 (en) 1986-11-20 1986-11-20 Therapeutic agents

Publications (2)

Publication Number Publication Date
PT86115A PT86115A (en) 1987-12-01
PT86115B true PT86115B (pt) 1990-08-31

Family

ID=10607612

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86115A PT86115B (pt) 1986-11-20 1987-11-11 Processo de preparacao de 7(4h)-tieno{3,2-b}-piridinonas

Country Status (24)

Country Link
US (1) US4877793A (de)
EP (1) EP0269295B1 (de)
JP (1) JPS63141984A (de)
KR (1) KR880006247A (de)
CN (1) CN1019491B (de)
AT (1) ATE64736T1 (de)
AU (1) AU599721B2 (de)
DD (1) DD282690A5 (de)
DE (1) DE3771039D1 (de)
DK (1) DK599887A (de)
ES (1) ES2038188T3 (de)
FI (1) FI875020L (de)
GB (1) GB8627698D0 (de)
GR (1) GR3002500T3 (de)
HU (1) HU198060B (de)
IL (1) IL84505A (de)
JO (1) JO1520B1 (de)
MX (1) MX9428A (de)
NO (1) NO874834L (de)
NZ (1) NZ222554A (de)
PH (1) PH23293A (de)
PL (1) PL149617B1 (de)
PT (1) PT86115B (de)
ZA (1) ZA878306B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
NZ230711A (en) * 1988-09-23 1990-10-26 Ortho Pharma Corp Substituted thienopyrans as antihypertensive agents
US5026700A (en) * 1989-05-16 1991-06-25 Merrell Dow Pharmaceuticals Certain quinolines and thienopyridines as excitatory amino acid antagonists
NZ233641A (en) * 1989-05-16 1992-07-28 Merrell Dow Pharma Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
JP2699794B2 (ja) * 1992-03-12 1998-01-19 三菱化学株式会社 チエノ〔３，２−ｂ〕ピリジン誘導体
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
RU2150470C1 (ru) * 1994-04-19 2000-06-10 Такеда Кемикал Индастриз Лтд. Бициклические производные тиофена, способ их получения и композиция на их основе
JP2002522388A (ja) * 1998-08-03 2002-07-23 ビーエーエスエフ コーポレーション 性機能障害の治療のためのピリジノン
US6562838B2 (en) 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US8329924B2 (en) 2001-06-11 2012-12-11 Vertex Pharmaceuticals (Canada) Incorporated Compounds and methods for the treatment or prevention of Flavivirus infections
AU2002344854B2 (en) * 2001-06-11 2008-11-06 Vertex Pharmaceuticals (Canada) Incorporated Thiophene derivatives as antiviral agents for flavivirus infection
WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038117A1 (es) 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
AR038118A1 (es) 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
CN100413861C (zh) 2002-12-10 2008-08-27 维勒凯姆制药股份有限公司 用于治疗或预防黄病毒感染的化合物
CN101218224B (zh) 2005-05-13 2013-05-08 Viro化学制药公司 治疗或预防黄病毒感染的组合物和方法
JP2008093872A (ja) * 2006-10-09 2008-04-24 Kouritsu Kogyo:Kk 表示装置
PT2104674E (pt) 2006-11-15 2013-07-26 Virochem Pharma Inc Análogos de tiofeno para o tratamento ou prevenção de infeções por flavivírus
SI2280952T1 (sl) * 2008-05-05 2012-09-28 Merck Patent Gmbh Derivati tienopiridona kot aktivatorji AMP-aktivirane protein kinaze (AMPK)
CN103517936A (zh) * 2011-04-27 2014-01-15 巴斯夫欧洲公司 基于二噻吩并吡啶酮共聚物的半导体材料
RS62430B1 (sr) * 2017-05-11 2021-11-30 Bristol Myers Squibb Co Tienopiridini i benzotiofeni korisni kao irak4 inhibitori

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903095A (en) * 1972-02-18 1975-09-02 Merck & Co Inc Certain substituted-thieno{8 3,2-c{9 -pyridines
US3997545A (en) * 1973-07-23 1976-12-14 Takeda Chemical Industries, Ltd. Thienopyridine-carboxylic acid derivatives
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
JPS5742690A (en) * 1980-08-28 1982-03-10 Kanebo Ltd Thieno 3,2-b pyridinecarboxylic acid derivative
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
EP0126970A3 (de) * 1983-04-27 1985-11-06 Beecham Group Plc Anxiolytische und anti-depressante Thienopyridinderivate
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
DE3578374D1 (de) * 1984-01-13 1990-08-02 Boots Co Ltd Verwendung von chinolonen fuer die herstellung eines arzneimittels zur behandlung von herzerkrankungen.
GB2161524B (en) * 1984-07-13 1988-01-06 Pandrol Ltd Improvements in or relating to rail pads and rail assemblies including such pads
EP0172004B1 (de) * 1984-08-15 1990-03-21 The Boots Company PLC Chinolinone, Verfahren zu ihrer Herstellung und die sie enthaltenden pharmazeutischen Präparate
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
JPS63141984A (ja) 1988-06-14
NO874834D0 (no) 1987-11-19
IL84505A (en) 1990-12-23
HUT47289A (en) 1989-02-28
MX9428A (es) 1993-10-01
PL268925A1 (en) 1988-09-01
FI875020A7 (fi) 1988-05-21
CN1019491B (zh) 1992-12-16
NO874834L (no) 1988-05-24
EP0269295B1 (de) 1991-06-26
HU198060B (en) 1989-07-28
PH23293A (en) 1989-06-30
CN87107975A (zh) 1988-06-01
ES2038188T3 (es) 1993-07-16
GR3002500T3 (en) 1992-12-30
EP0269295A1 (de) 1988-06-01
DK599887D0 (da) 1987-11-16
AU8144087A (en) 1988-05-26
DK599887A (da) 1988-05-21
DE3771039D1 (de) 1991-08-01
FI875020L (fi) 1988-05-21
US4877793A (en) 1989-10-31
PL149617B1 (en) 1990-03-31
AU599721B2 (en) 1990-07-26
FI875020A0 (fi) 1987-11-13
ZA878306B (en) 1988-05-02
ATE64736T1 (de) 1991-07-15
GB8627698D0 (en) 1986-12-17
PT86115A (en) 1987-12-01
NZ222554A (en) 1989-08-29
JO1520B1 (en) 1989-01-25
KR880006247A (ko) 1988-07-22
DD282690A5 (de) 1990-09-19

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930831