ATE64736T1 - Therapeutisches mittel. - Google Patents

Therapeutisches mittel.

Info

Publication number
ATE64736T1
ATE64736T1 AT87309788T AT87309788T ATE64736T1 AT E64736 T1 ATE64736 T1 AT E64736T1 AT 87309788 T AT87309788 T AT 87309788T AT 87309788 T AT87309788 T AT 87309788T AT E64736 T1 ATE64736 T1 AT E64736T1
Authority
AT
Austria
Prior art keywords
lower alkyl
therapeutic agent
halo
trifluoromethyl
novel
Prior art date
Application number
AT87309788T
Other languages
English (en)
Inventor
Roy Victor Davies
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Application granted granted Critical
Publication of ATE64736T1 publication Critical patent/ATE64736T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
AT87309788T 1986-11-20 1987-11-05 Therapeutisches mittel. ATE64736T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868627698A GB8627698D0 (en) 1986-11-20 1986-11-20 Therapeutic agents
EP87309788A EP0269295B1 (de) 1986-11-20 1987-11-05 Therapeutisches Mittel

Publications (1)

Publication Number Publication Date
ATE64736T1 true ATE64736T1 (de) 1991-07-15

Family

ID=10607612

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87309788T ATE64736T1 (de) 1986-11-20 1987-11-05 Therapeutisches mittel.

Country Status (24)

Country Link
US (1) US4877793A (de)
EP (1) EP0269295B1 (de)
JP (1) JPS63141984A (de)
KR (1) KR880006247A (de)
CN (1) CN1019491B (de)
AT (1) ATE64736T1 (de)
AU (1) AU599721B2 (de)
DD (1) DD282690A5 (de)
DE (1) DE3771039D1 (de)
DK (1) DK599887A (de)
ES (1) ES2038188T3 (de)
FI (1) FI875020L (de)
GB (1) GB8627698D0 (de)
GR (1) GR3002500T3 (de)
HU (1) HU198060B (de)
IL (1) IL84505A (de)
JO (1) JO1520B1 (de)
MX (1) MX9428A (de)
NO (1) NO874834L (de)
NZ (1) NZ222554A (de)
PH (1) PH23293A (de)
PL (1) PL149617B1 (de)
PT (1) PT86115B (de)
ZA (1) ZA878306B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
NZ230711A (en) * 1988-09-23 1990-10-26 Ortho Pharma Corp Substituted thienopyrans as antihypertensive agents
US5026700A (en) * 1989-05-16 1991-06-25 Merrell Dow Pharmaceuticals Certain quinolines and thienopyridines as excitatory amino acid antagonists
ZA903588B (en) * 1989-05-16 1991-02-27 Merrell Dow Pharma Excitatory amino acid antagonists
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
JP2699794B2 (ja) * 1992-03-12 1998-01-19 三菱化学株式会社 チエノ〔３，２−ｂ〕ピリジン誘導体
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
RU2150470C1 (ru) * 1994-04-19 2000-06-10 Такеда Кемикал Индастриз Лтд. Бициклические производные тиофена, способ их получения и композиция на их основе
AU5509099A (en) * 1998-08-03 2000-02-28 Basf Corporation Pyridinones for the treatment of sexual dysfunction
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6562838B2 (en) 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
EA007484B1 (ru) * 2001-06-11 2006-10-27 Вирокем Фарма Инк. Соединения и способы лечения или предупреждения инфекций flavivirus
US8329924B2 (en) 2001-06-11 2012-12-11 Vertex Pharmaceuticals (Canada) Incorporated Compounds and methods for the treatment or prevention of Flavivirus infections
WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038118A1 (es) 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
AR038117A1 (es) 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038294A1 (es) * 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
PT1569929E (pt) 2002-12-10 2010-06-18 Virochem Pharma Inc Compostos e métodos para o tratamento ou prevenção de infecções por flavivírus
NZ563909A (en) 2005-05-13 2011-10-28 Virochem Pharma Inc Thiophene derivatives and their use for the treatment or prevention of flavivirus infections
JP2008093872A (ja) * 2006-10-09 2008-04-24 Kouritsu Kogyo:Kk 表示装置
NZ576780A (en) 2006-11-15 2011-12-22 Virochem Pharma Inc Thiophene analogues for the treatment or prevention of flavivirus infections
AU2009243811B2 (en) * 2008-05-05 2014-04-10 Merck Patent Gmbh Thienopyridone derivatives as AMP-activated protein kinase (AMPK) activators
CN103517936A (zh) * 2011-04-27 2014-01-15 巴斯夫欧洲公司 基于二噻吩并吡啶酮共聚物的半导体材料
EA039189B1 (ru) * 2017-05-11 2021-12-15 Бристол-Маерс Сквибб Компани Тиенопиридины и бензотиофены в качестве ингибиторов irak4

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903095A (en) * 1972-02-18 1975-09-02 Merck & Co Inc Certain substituted-thieno{8 3,2-c{9 -pyridines
US3997545A (en) * 1973-07-23 1976-12-14 Takeda Chemical Industries, Ltd. Thienopyridine-carboxylic acid derivatives
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
JPS5742690A (en) * 1980-08-28 1982-03-10 Kanebo Ltd Thieno 3,2-b pyridinecarboxylic acid derivative
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
EP0126970A3 (de) * 1983-04-27 1985-11-06 Beecham Group Plc Anxiolytische und anti-depressante Thienopyridinderivate
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
DE3578374D1 (de) * 1984-01-13 1990-08-02 Boots Co Ltd Verwendung von chinolonen fuer die herstellung eines arzneimittels zur behandlung von herzerkrankungen.
GB2161524B (en) * 1984-07-13 1988-01-06 Pandrol Ltd Improvements in or relating to rail pads and rail assemblies including such pads
EP0172004B1 (de) * 1984-08-15 1990-03-21 The Boots Company PLC Chinolinone, Verfahren zu ihrer Herstellung und die sie enthaltenden pharmazeutischen Präparate
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
KR880006247A (ko) 1988-07-22
CN87107975A (zh) 1988-06-01
NZ222554A (en) 1989-08-29
ES2038188T3 (es) 1993-07-16
DK599887D0 (da) 1987-11-16
EP0269295B1 (de) 1991-06-26
IL84505A (en) 1990-12-23
CN1019491B (zh) 1992-12-16
US4877793A (en) 1989-10-31
HU198060B (en) 1989-07-28
JO1520B1 (en) 1989-01-25
MX9428A (es) 1993-10-01
GR3002500T3 (en) 1992-12-30
AU599721B2 (en) 1990-07-26
AU8144087A (en) 1988-05-26
ZA878306B (en) 1988-05-02
EP0269295A1 (de) 1988-06-01
HUT47289A (en) 1989-02-28
FI875020A7 (fi) 1988-05-21
DK599887A (da) 1988-05-21
NO874834L (no) 1988-05-24
PT86115B (pt) 1990-08-31
DD282690A5 (de) 1990-09-19
DE3771039D1 (de) 1991-08-01
PH23293A (en) 1989-06-30
JPS63141984A (ja) 1988-06-14
FI875020L (fi) 1988-05-21
PL149617B1 (en) 1990-03-31
NO874834D0 (no) 1987-11-19
PL268925A1 (en) 1988-09-01
FI875020A0 (fi) 1987-11-13
GB8627698D0 (en) 1986-12-17
PT86115A (en) 1987-12-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee