PH23293A - Hypotensive quinolone derivatives - Google Patents

Hypotensive quinolone derivatives

Info

Publication number
PH23293A
PH23293A PH36041A PH36041A PH23293A PH 23293 A PH23293 A PH 23293A PH 36041 A PH36041 A PH 36041A PH 36041 A PH36041 A PH 36041A PH 23293 A PH23293 A PH 23293A
Authority
PH
Philippines
Prior art keywords
hypotensive
lower alkyl
quinolone derivatives
halo
trifluoromethyl
Prior art date
Application number
PH36041A
Other languages
English (en)
Inventor
Roy Victor Davies
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of PH23293A publication Critical patent/PH23293A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Crystal Substances (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PH36041A 1986-11-20 1987-11-06 Hypotensive quinolone derivatives PH23293A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868627698A GB8627698D0 (en) 1986-11-20 1986-11-20 Therapeutic agents

Publications (1)

Publication Number Publication Date
PH23293A true PH23293A (en) 1989-06-30

Family

ID=10607612

Family Applications (1)

Application Number Title Priority Date Filing Date
PH36041A PH23293A (en) 1986-11-20 1987-11-06 Hypotensive quinolone derivatives

Country Status (24)

Country Link
US (1) US4877793A (de)
EP (1) EP0269295B1 (de)
JP (1) JPS63141984A (de)
KR (1) KR880006247A (de)
CN (1) CN1019491B (de)
AT (1) ATE64736T1 (de)
AU (1) AU599721B2 (de)
DD (1) DD282690A5 (de)
DE (1) DE3771039D1 (de)
DK (1) DK599887A (de)
ES (1) ES2038188T3 (de)
FI (1) FI875020A (de)
GB (1) GB8627698D0 (de)
GR (1) GR3002500T3 (de)
HU (1) HU198060B (de)
IL (1) IL84505A (de)
JO (1) JO1520B1 (de)
MX (1) MX9428A (de)
NO (1) NO874834L (de)
NZ (1) NZ222554A (de)
PH (1) PH23293A (de)
PL (1) PL149617B1 (de)
PT (1) PT86115B (de)
ZA (1) ZA878306B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
NZ230711A (en) * 1988-09-23 1990-10-26 Ortho Pharma Corp Substituted thienopyrans as antihypertensive agents
NZ233641A (en) * 1989-05-16 1992-07-28 Merrell Dow Pharma Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions
US5026700A (en) * 1989-05-16 1991-06-25 Merrell Dow Pharmaceuticals Certain quinolines and thienopyridines as excitatory amino acid antagonists
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
JP2699794B2 (ja) * 1992-03-12 1998-01-19 三菱化学株式会社 チエノ〔3,2−b〕ピリジン誘導体
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
CA2339484A1 (en) * 1998-08-03 2000-02-17 Robert A. O'brien Pyridinones for the treatment of sexual dysfunction
US6562838B2 (en) 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
AP1753A (en) * 2001-06-11 2007-07-18 Shire Biochem Inc Thiophene derivatives as antiviral agents for flavvivirus infection
US8329924B2 (en) 2001-06-11 2012-12-11 Vertex Pharmaceuticals (Canada) Incorporated Compounds and methods for the treatment or prevention of Flavivirus infections
WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
AR038117A1 (es) 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038118A1 (es) 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
KR101058696B1 (ko) 2002-12-10 2011-08-22 바이로켐 파마 인코포레이티드 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법
ES2415742T3 (es) 2005-05-13 2013-07-26 Vertex Pharmaceuticals (Canada) Incorporated Compuestos y procedimientos para el tratamiento o prevención de infecciones por flavivirus
JP2008093872A (ja) * 2006-10-09 2008-04-24 Kouritsu Kogyo:Kk 表示装置
EA201101492A1 (ru) 2006-11-15 2012-09-28 Вирокем Фарма Инк. Аналоги тиофена для лечения или предупреждения флавивирусных инфекций
MX2010011916A (es) * 2008-05-05 2010-11-26 Merck Patent Gmbh Derivados de tienopiridonas como activadores de proteinas cinasa activados por amp (ampk).
KR101486693B1 (ko) * 2011-04-27 2015-01-26 바스프 에스이 디티에노피리돈 공중합체 기재의 반도체 물질
MX2019012929A (es) * 2017-05-11 2020-01-14 Bristol Myers Squibb Co Tienopiridinas y benzotiofenos utiles como inhibidores de cinasa 4 asociada al receptor de interleucina 1 (irak4).

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903095A (en) * 1972-02-18 1975-09-02 Merck & Co Inc Certain substituted-thieno{8 3,2-c{9 -pyridines
US3997545A (en) * 1973-07-23 1976-12-14 Takeda Chemical Industries, Ltd. Thienopyridine-carboxylic acid derivatives
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
JPS5742690A (en) * 1980-08-28 1982-03-10 Kanebo Ltd Thieno 3,2-b pyridinecarboxylic acid derivative
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
EP0126970A3 (de) * 1983-04-27 1985-11-06 Beecham Group Plc Anxiolytische und anti-depressante Thienopyridinderivate
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
DE3578374D1 (de) * 1984-01-13 1990-08-02 Boots Co Ltd Verwendung von chinolonen fuer die herstellung eines arzneimittels zur behandlung von herzerkrankungen.
DE3575961D1 (de) * 1984-07-13 1990-03-15 Pandrol Ltd Schienenunterlagen.
DE3576686D1 (de) * 1984-08-15 1990-04-26 Boots Co Ltd Chinolinone, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen praeparate.
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
DK599887A (da) 1988-05-21
GR3002500T3 (en) 1992-12-30
FI875020A (fi) 1988-05-21
JO1520B1 (en) 1989-01-25
HU198060B (en) 1989-07-28
MX9428A (es) 1993-10-01
HUT47289A (en) 1989-02-28
GB8627698D0 (en) 1986-12-17
IL84505A (en) 1990-12-23
JPS63141984A (ja) 1988-06-14
US4877793A (en) 1989-10-31
FI875020A0 (fi) 1987-11-13
AU599721B2 (en) 1990-07-26
NO874834D0 (no) 1987-11-19
PT86115A (en) 1987-12-01
ZA878306B (en) 1988-05-02
CN87107975A (zh) 1988-06-01
DK599887D0 (da) 1987-11-16
EP0269295B1 (de) 1991-06-26
ES2038188T3 (es) 1993-07-16
CN1019491B (zh) 1992-12-16
KR880006247A (ko) 1988-07-22
DD282690A5 (de) 1990-09-19
ATE64736T1 (de) 1991-07-15
DE3771039D1 (de) 1991-08-01
NO874834L (no) 1988-05-24
PT86115B (pt) 1990-08-31
PL268925A1 (en) 1988-09-01
NZ222554A (en) 1989-08-29
PL149617B1 (en) 1990-03-31
EP0269295A1 (de) 1988-06-01
AU8144087A (en) 1988-05-26

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