PT77469B - Procede de preparation de nouveaux derives de la 6-amino-7-hydroxy 4,5,6,7-tetrahydroimidazo/4,5,1-j-k/-/1/benzazepin-2(1h)-one et de leurs sels - Google Patents

Procede de preparation de nouveaux derives de la 6-amino-7-hydroxy 4,5,6,7-tetrahydroimidazo/4,5,1-j-k/-/1/benzazepin-2(1h)-one et de leurs sels

Info

Publication number
PT77469B
PT77469B PT77469A PT7746983A PT77469B PT 77469 B PT77469 B PT 77469B PT 77469 A PT77469 A PT 77469A PT 7746983 A PT7746983 A PT 7746983A PT 77469 B PT77469 B PT 77469B
Authority
PT
Portugal
Prior art keywords
amino
carbon atoms
benzazepin
hydroxy
derivatives
Prior art date
Application number
PT77469A
Other languages
English (en)
French (fr)
Portuguese (pt)
Other versions
PT77469A (fr
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT77469A publication Critical patent/PT77469A/pt
Publication of PT77469B publication Critical patent/PT77469B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT77469A 1982-10-12 1983-10-07 Procede de preparation de nouveaux derives de la 6-amino-7-hydroxy 4,5,6,7-tetrahydroimidazo/4,5,1-j-k/-/1/benzazepin-2(1h)-one et de leurs sels PT77469B (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8217054A FR2534257A1 (fr) 1982-10-12 1982-10-12 Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire

Publications (2)

Publication Number Publication Date
PT77469A PT77469A (fr) 1983-11-01
PT77469B true PT77469B (fr) 1986-05-07

Family

ID=9278183

Family Applications (1)

Application Number Title Priority Date Filing Date
PT77469A PT77469B (fr) 1982-10-12 1983-10-07 Procede de preparation de nouveaux derives de la 6-amino-7-hydroxy 4,5,6,7-tetrahydroimidazo/4,5,1-j-k/-/1/benzazepin-2(1h)-one et de leurs sels

Country Status (23)

Country Link
US (1) US4585770A (forum.php)
EP (1) EP0107569B1 (forum.php)
JP (1) JPS59130289A (forum.php)
KR (1) KR900006753B1 (forum.php)
AT (1) ATE25981T1 (forum.php)
AU (1) AU559422B2 (forum.php)
CA (2) CA1216847A (forum.php)
DD (1) DD215784A5 (forum.php)
DE (1) DE3370332D1 (forum.php)
DK (1) DK163734C (forum.php)
ES (1) ES526390A0 (forum.php)
FI (1) FI76340C (forum.php)
FR (1) FR2534257A1 (forum.php)
GR (1) GR78731B (forum.php)
HU (1) HU188499B (forum.php)
IE (1) IE59441B1 (forum.php)
IL (1) IL69993A (forum.php)
MX (1) MX8495A (forum.php)
NZ (1) NZ205918A (forum.php)
PH (1) PH20031A (forum.php)
PT (1) PT77469B (forum.php)
SU (2) SU1287753A3 (forum.php)
ZA (1) ZA837480B (forum.php)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2608047B1 (fr) * 1986-12-11 1990-08-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5,1-j-k/ /1/ benzazepin-2-(1h)-one
HU203667B (en) * 1986-12-11 1991-09-30 Roussel Uclaf Process for producing synergetic zootechnical compositions containing three components
AU616390B2 (en) * 1986-12-11 1991-10-31 Hoechst Roussel Vet S.A. Zootechnical compositions containing a beta-adrenergic
FR2608046B1 (fr) * 1986-12-11 1989-03-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5, 1-j-k/ /1/benzazepin-2-(1h)-one
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them
NZ271071A (en) * 1993-07-13 1996-08-27 Janssen Pharmaceutica Nv Aryl- or benzo-imidazoazepine derivatives {typically 7,10-dihydro-7-methyl-10-(1-methyl-4-piperidinylidene)imida zo[1,2-a]pyrrolo[3,2-d]-azepin-6(5h)-one}; intermediates including 1-esterified-2-[disubstitutedmethyl-1h-imidazole
FR2735474B1 (fr) * 1995-06-13 1997-08-08 Roussel Uclaf Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
US7207289B2 (en) * 2004-05-20 2007-04-24 Intervet International B.V. Method of feeding the cattle with feed additives that increases beef production and reduces liver abscess
JP2010505938A (ja) * 2006-10-13 2010-02-25 ファイザー・リミテッド 家畜動物用の同化剤として有用な複素環式化合物
WO2008050207A1 (en) * 2006-10-25 2008-05-02 Pfizer Limited Heterocyclic compounds useful as anabolic agents for livestock animals
MX2009008158A (es) * 2007-02-01 2009-09-23 Intervet Int Bv Sintesis enantioselectiva de 6-amino-7-hidroxi-4,5,6,7-tetrahidro- imidazo[4,5,1-jk][1]-benzazepin-2[1h]-ona y zilpaterol.
RU2442786C2 (ru) * 2007-03-31 2012-02-20 Интервет Интернэшнл Б.В. Способы получения зилпатерола и его солей
JP5856990B2 (ja) * 2007-03-31 2016-02-10 インターベット インターナショナル ベー． フェー． ジルパテロールおよびこの塩の製造方法
KR101240147B1 (ko) * 2007-03-31 2013-03-08 인터벳 인터내셔널 비.브이. 질파테롤 및 이의 염의 제조 방법
EP2142553B1 (en) 2007-03-31 2015-08-19 Intervet International B.V. Processes for making zilpaterol and salts thereof
EP1995248A1 (en) * 2007-05-23 2008-11-26 Evonik Degussa GmbH Process for the production of amino alcohols by asymmetric hydrogenation
MX2010006223A (es) 2007-12-06 2010-08-10 Intervet Int Bv Terapias de combinacion usando acetato de melengestrol y zilpaterol o sus sales.
TW201033217A (en) 2008-12-17 2010-09-16 Intervet Int Bv Process for making a crystalline zilpaterol salt
US20130310367A1 (en) 2012-05-18 2013-11-21 John A. Rogers Method of enhancing performance in broiler chickens
JP6310480B2 (ja) * 2012-12-18 2018-04-11 インターベット インターナショナル ベー． フェー． ジルパテロールを作製するための改善されたプロセス
CA2902257A1 (en) 2013-03-15 2014-09-18 Intervet International B.V. A method of improving the efficiency of beef production from bovine animals
CN104418808A (zh) * 2013-09-11 2015-03-18 中美华世通生物医药科技（武汉）有限公司 一种适于工业化生产的中间体Buzolic acid的制备方法
CN103554113B (zh) * 2013-09-25 2016-04-27 湖北美天生物科技有限公司 一种盐酸齐帕特罗的合成方法
MX2018000862A (es) 2015-07-21 2018-05-15 Intervet Int Bv Una novedosa formulacion de premezcla animal de zilpaterol.
EP3488705A1 (en) 2017-11-23 2019-05-29 Saviela AG Solubilized growth promoting product to be applied orally to animals and method for the respective feed preparation
CN108752352B (zh) * 2018-04-18 2019-11-26 江苏凌云药业股份有限公司 一种盐酸齐帕特罗的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2320439A (en) * 1943-06-01 Bottle carrier
US3200123A (en) * 1962-01-26 1965-08-10 Richardson Merreil Inc Imidazoquinolines
DE3161072D1 (en) * 1980-02-26 1983-11-10 Roussel Uclaf Cycloheptindolol derivatives and their acid-addition salts, their preparation, their use as medicines and composition containing them

Also Published As

Publication number Publication date
FR2534257A1 (fr) 1984-04-13
IL69993A (en) 1987-10-30
GR78731B (forum.php) 1984-10-02
ZA837480B (en) 1984-11-28
JPS59130289A (ja) 1984-07-26
IE832387L (en) 1984-04-12
FI76340C (fi) 1988-10-10
FI833697L (fi) 1984-04-13
DK466483A (da) 1984-04-13
FI76340B (fi) 1988-06-30
FI833697A0 (fi) 1983-10-11
KR840006484A (ko) 1984-11-30
AU2005383A (en) 1984-04-19
DK163734B (da) 1992-03-30
PH20031A (en) 1986-09-04
EP0107569B1 (fr) 1987-03-18
AU559422B2 (en) 1987-03-12
SU1384201A3 (ru) 1988-03-23
SU1287753A3 (ru) 1987-01-30
DK163734C (da) 1992-08-31
EP0107569A1 (fr) 1984-05-02
DD215784A5 (de) 1984-11-21
CA1216847A (fr) 1987-01-20
US4585770A (en) 1986-04-29
NZ205918A (en) 1985-12-13
IL69993A0 (en) 1984-01-31
ES8405802A1 (es) 1984-06-16
MX8495A (es) 1993-09-01
HU188499B (en) 1986-04-28
KR900006753B1 (ko) 1990-09-20
DE3370332D1 (en) 1987-04-23
FR2534257B1 (forum.php) 1984-12-28
CA1222246A (fr) 1987-05-26
DK466483D0 (da) 1983-10-11
ES526390A0 (es) 1984-06-16
PT77469A (fr) 1983-11-01
JPH0454671B2 (forum.php) 1992-08-31
IE59441B1 (en) 1994-02-23
ATE25981T1 (de) 1987-04-15

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Legal Events

Date Code Title Description
PC3A Transfer or assignment

Free format text: 20000720 HOECHST ROUSSEL VET S.A. FR