PT2809320T - (1r,4r)-6'-fluoro-(n-metil ou n,n-dimetil)-4-fenil-4',9'-di-hidro-3'h-espiro[ciclo-hexano-1,1'-pirano-[3,4,b]indol]-4-amina para o tratamento de fibromialgia e de síndrome de fadiga crónica - Google Patents
(1r,4r)-6'-fluoro-(n-metil ou n,n-dimetil)-4-fenil-4',9'-di-hidro-3'h-espiro[ciclo-hexano-1,1'-pirano-[3,4,b]indol]-4-amina para o tratamento de fibromialgia e de síndrome de fadiga crónica Download PDFInfo
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- PT2809320T PT2809320T PT137018073T PT13701807T PT2809320T PT 2809320 T PT2809320 T PT 2809320T PT 137018073 T PT137018073 T PT 137018073T PT 13701807 T PT13701807 T PT 13701807T PT 2809320 T PT2809320 T PT 2809320T
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- fibromyalgia
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- pharmaceutical dosage
- chronic fatigue
- fatigue syndrome
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
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| EP12000743 | 2012-02-03 |
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| PT2809320T true PT2809320T (pt) | 2017-06-30 |
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| PT137018073T PT2809320T (pt) | 2012-02-03 | 2013-02-01 | (1r,4r)-6'-fluoro-(n-metil ou n,n-dimetil)-4-fenil-4',9'-di-hidro-3'h-espiro[ciclo-hexano-1,1'-pirano-[3,4,b]indol]-4-amina para o tratamento de fibromialgia e de síndrome de fadiga crónica |
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|---|---|
| US (1) | US20130202701A1 (https=) |
| EP (1) | EP2809320B1 (https=) |
| JP (1) | JP6126134B2 (https=) |
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| CN (1) | CN104168897B (https=) |
| AU (1) | AU2013214223B2 (https=) |
| BR (1) | BR112014019136A8 (https=) |
| CA (1) | CA2863572C (https=) |
| CY (1) | CY1118799T1 (https=) |
| DK (1) | DK2809320T3 (https=) |
| EA (1) | EA025500B1 (https=) |
| ES (1) | ES2629211T3 (https=) |
| HR (1) | HRP20170581T1 (https=) |
| IL (1) | IL233871B (https=) |
| LT (1) | LT2809320T (https=) |
| MX (1) | MX353740B (https=) |
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| PL (1) | PL2809320T3 (https=) |
| PT (1) | PT2809320T (https=) |
| RS (1) | RS56097B1 (https=) |
| SI (1) | SI2809320T1 (https=) |
| WO (1) | WO2013113857A1 (https=) |
| ZA (1) | ZA201406447B (https=) |
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| US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
| DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10360792A1 (de) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| US7354925B2 (en) * | 2004-03-29 | 2008-04-08 | Pfizer Inc. | Alpha aryl or heteroaryl methyl beta piperidino propanamide compounds as ORL1-receptor antagonists |
| AU2007254751A1 (en) * | 2006-05-31 | 2007-12-13 | Sepracor Inc. | Treatment of pain disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine and its formamide |
| DE102006046745A1 (de) * | 2006-09-29 | 2008-04-03 | Grünenthal GmbH | Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz |
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| SI2809320T1 (sl) | 2017-07-31 |
| IL233871B (en) | 2018-06-28 |
| CN104168897B (zh) | 2016-09-28 |
| EP2809320A1 (en) | 2014-12-10 |
| KR20140130695A (ko) | 2014-11-11 |
| JP2015505553A (ja) | 2015-02-23 |
| US20130202701A1 (en) | 2013-08-08 |
| MX2014008865A (es) | 2014-08-27 |
| JP6126134B2 (ja) | 2017-05-10 |
| BR112014019136A8 (pt) | 2017-07-11 |
| EA025500B1 (ru) | 2016-12-30 |
| LT2809320T (lt) | 2017-05-25 |
| WO2013113857A1 (en) | 2013-08-08 |
| EA201400857A1 (ru) | 2015-01-30 |
| CN104168897A (zh) | 2014-11-26 |
| PL2809320T3 (pl) | 2017-09-29 |
| RS56097B1 (sr) | 2017-10-31 |
| IL233871A0 (en) | 2014-09-30 |
| KR102061482B1 (ko) | 2020-01-03 |
| CA2863572C (en) | 2019-08-27 |
| HK1199218A1 (en) | 2015-06-26 |
| BR112014019136A2 (https=) | 2017-06-20 |
| CA2863572A1 (en) | 2013-08-08 |
| ZA201406447B (en) | 2016-02-24 |
| DK2809320T3 (en) | 2017-05-15 |
| MX353740B (es) | 2018-01-26 |
| CY1118799T1 (el) | 2018-01-10 |
| AU2013214223A1 (en) | 2014-09-18 |
| HRP20170581T1 (hr) | 2017-06-16 |
| ES2629211T3 (es) | 2017-08-07 |
| NZ629800A (en) | 2016-06-24 |
| EP2809320B1 (en) | 2017-03-22 |
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