PT2578571E - Moduladores de transportadores de atp-binding cassette - Google Patents

Moduladores de transportadores de atp-binding cassette Download PDF

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Publication number
PT2578571E
PT2578571E PT121813703T PT08181370T PT2578571E PT 2578571 E PT2578571 E PT 2578571E PT 121813703 T PT121813703 T PT 121813703T PT 08181370 T PT08181370 T PT 08181370T PT 2578571 E PT2578571 E PT 2578571E
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PT
Portugal
Prior art keywords
aliphatic
cycloaliphatic
heterocycloaliphatic
optionally substituted
carbonyl
Prior art date
Application number
PT121813703T
Other languages
English (en)
Portuguese (pt)
Inventor
Peter D J Grootenhuis
Brian Bear
Jinglan Zhou
Sara Hadida Ruah
Miller Mark
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PT2578571E publication Critical patent/PT2578571E/pt

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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PT121813703T 2007-11-16 2008-11-14 Moduladores de transportadores de atp-binding cassette PT2578571E (pt)

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Application Number Priority Date Filing Date Title
US98855907P 2007-11-16 2007-11-16

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PT2578571E true PT2578571E (pt) 2015-11-30

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PT121813703T PT2578571E (pt) 2007-11-16 2008-11-14 Moduladores de transportadores de atp-binding cassette
PT08849242T PT2217572E (pt) 2007-11-16 2008-11-14 Moduladores de isoquinolina de transportadores de cassete de ligação a atp

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PT08849242T PT2217572E (pt) 2007-11-16 2008-11-14 Moduladores de isoquinolina de transportadores de cassete de ligação a atp

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US (4) US8507524B2 (enExample)
EP (3) EP2578571B1 (enExample)
JP (3) JP5646338B2 (enExample)
CN (2) CN102743385B (enExample)
AU (1) AU2008322616B2 (enExample)
CA (1) CA2705562C (enExample)
CY (1) CY1115318T1 (enExample)
DK (2) DK2217572T3 (enExample)
ES (3) ES2445447T3 (enExample)
HR (2) HRP20140103T1 (enExample)
HU (1) HUE026334T2 (enExample)
NZ (2) NZ598941A (enExample)
PL (2) PL2578571T3 (enExample)
PT (2) PT2578571E (enExample)
SI (2) SI2578571T1 (enExample)
WO (1) WO2009064959A1 (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7973169B2 (en) 2003-09-06 2011-07-05 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
ATE437640T1 (de) * 2003-11-14 2009-08-15 Vertex Pharma Thiazole udn oxazole als modulatoren von atp- bindungs-kassetten-transportern
EP3219709B1 (en) * 2004-01-30 2020-03-18 Vertex Pharmaceuticals Incorporated Intermediate compound of modulators of atp-binding cassette transporters
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
PL2502911T3 (pl) 2004-06-24 2017-09-29 Vertex Pharma Modulatory transporterów kasety wiążącej ATP
CA2618057A1 (en) 2005-08-11 2007-02-22 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
DK1945632T3 (da) 2005-11-08 2013-12-16 Vertex Pharma Heterocycliske modulatorer af ATP-bindende kassettetransportører
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