PT1820853E - Vírus recombinante da gripe para vacinas e terapia genética - Google Patents
Vírus recombinante da gripe para vacinas e terapia genética Download PDFInfo
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- PT1820853E PT1820853E PT07009953T PT07009953T PT1820853E PT 1820853 E PT1820853 E PT 1820853E PT 07009953 T PT07009953 T PT 07009953T PT 07009953 T PT07009953 T PT 07009953T PT 1820853 E PT1820853 E PT 1820853E
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
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- C12N2760/16123—Virus like particles [VLP]
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16141—Use of virus, viral particle or viral elements as a vector
- C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
- C12N2810/6081—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12791299P | 1999-04-06 | 1999-04-06 | |
| US13283999P | 1999-05-06 | 1999-05-06 |
Publications (1)
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| PT1820853E true PT1820853E (pt) | 2012-01-03 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| PT07009953T PT1820853E (pt) | 1999-04-06 | 2000-04-05 | Vírus recombinante da gripe para vacinas e terapia genética |
| PT00920151T PT1185615E (pt) | 1999-04-06 | 2000-04-05 | ''vírus da influenza recombinantes para vacinas e tratamento genético'' |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00920151T PT1185615E (pt) | 1999-04-06 | 2000-04-05 | ''vírus da influenza recombinantes para vacinas e tratamento genético'' |
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| EP (4) | EP2910629B1 (https=) |
| JP (3) | JP5543048B2 (https=) |
| KR (1) | KR100702275B1 (https=) |
| CN (2) | CN101851636B (https=) |
| AT (2) | ATE368729T1 (https=) |
| AU (1) | AU4073300A (https=) |
| BR (1) | BRPI0009580B8 (https=) |
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| MX (1) | MXPA01010082A (https=) |
| NL (2) | NL300365I2 (https=) |
| PT (2) | PT1820853E (https=) |
| WO (1) | WO2000060050A2 (https=) |
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| US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
| DE122008000035I1 (de) * | 1999-04-06 | 2009-05-20 | Wisconsin Alumni Res Found | Rekombinante influenzaviren zur vakzinherstellung und gentherapie |
| US8715940B2 (en) | 1999-04-06 | 2014-05-06 | Wisconsin Alumni Research Foundation | Method of making recombinant influenza virus |
| ES2278621T5 (es) * | 1999-07-14 | 2011-02-02 | Mount Sinai School Of Medicine Of New York University | Reconstrucción in vitro de virus arn segmentados de polaridad negativa. |
| GB9916794D0 (en) * | 1999-07-16 | 1999-09-22 | Isis Innovation | In vitro virus reconstitution |
| ES2319864T3 (es) | 2000-04-28 | 2009-05-14 | St. Jude Children's Research Hospital | Sistema de transfeccion de adn para la generacion de virus infecciosos de arn de cadena negativa. |
| EP1862550A1 (en) * | 2000-06-23 | 2007-12-05 | Wyeth Holdings Corporation | Assembly of wild-type and chimeric influenza virus-like particles (VLPs) |
| MXPA02012254A (es) | 2000-06-23 | 2003-04-25 | American Cyanamid Co | Montaje de particulas quimericas semejantes al virus de influenza y del tipo silvestre. |
| US7211378B2 (en) | 2002-01-31 | 2007-05-01 | Wisconsin Alumni Research Foundation | Filovirus vectors and noninfectious filovirus-based particles |
| KR101113432B1 (ko) * | 2002-02-13 | 2012-02-29 | 위스콘신 얼럼나이 리서어치 화운데이션 | 인플루엔자 바이러스 벡터의 패키징을 위한 신호 |
| US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
| DK1499348T3 (en) * | 2002-04-26 | 2015-01-05 | Medimmune Llc | PROCEDURE FOR PREPARING INFECTIOUS INFLUENZA B-VIRA IN CELL CULTURE |
| CA2525953C (en) * | 2003-05-28 | 2023-10-10 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines and gene therapy |
| US7566458B2 (en) | 2003-06-16 | 2009-07-28 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
| CA2551489C (en) | 2003-12-23 | 2013-09-03 | Gregory Duke | Multi plasmid system for the production of influenza virus |
| FR2866031B1 (fr) * | 2004-02-11 | 2012-10-19 | David Francois Joseph Millet | Chimere de virus pathogene emergent, medicament la contenant et utilisation en therapie antivirale |
| JP5600375B2 (ja) | 2004-03-09 | 2014-10-01 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | インフルエンザウイルスワクチン |
| JP4980895B2 (ja) | 2004-05-25 | 2012-07-18 | メディミューン，エルエルシー | インフルエンザ赤血球凝集素およびノイラミニダーゼ変異体 |
| EA200701097A1 (ru) | 2004-11-19 | 2007-10-26 | Висконсин Эламни Рисёч Фаундэйшн | Рекомбинантные векторы вируса гриппа с тандемными транскрипционными единицами |
| US7510719B2 (en) | 2004-12-08 | 2009-03-31 | Medimmune, Llc | Methods of producing influenza vaccine compositions |
| EP2295542B1 (en) | 2004-12-24 | 2013-01-30 | Abbott Biologicals B.V. | Rescue of influenza virus |
| EP2471552B1 (en) | 2005-03-08 | 2015-05-06 | MedImmune, LLC | Reassortant influenza viruses |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| JP2009514844A (ja) | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | スプリットインフルエンザワクチン用のアジュバントとしての遊離水相界面活性剤を含むエマルション |
| CA2628152C (en) * | 2005-11-04 | 2016-02-02 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| NZ568211A (en) | 2005-11-04 | 2011-11-25 | Novartis Vaccines & Diagnostic | Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
| CN102755645A (zh) | 2005-11-04 | 2012-10-31 | 诺华疫苗和诊断有限公司 | 佐剂配制的包含细胞因子诱导剂的流感疫苗 |
| PL2251034T3 (pl) | 2005-12-02 | 2018-07-31 | Icahn School Of Medicine At Mount Sinai | Chimeryczne wirusy prezentujące nienatywne białka powierzchniowe i zastosowania tych wirusów |
| PL2478916T3 (pl) | 2006-01-27 | 2020-11-16 | Seqirus UK Limited | Szczepionki przeciw grypie zawierające hemaglutyninę i białka macierzy |
| CN101448523A (zh) | 2006-03-24 | 2009-06-03 | 诺华疫苗和诊断有限两合公司 | 无需冷藏储存流感疫苗 |
| CA2647985C (en) | 2006-03-31 | 2014-12-30 | Warf-Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
| WO2007146057A2 (en) * | 2006-06-09 | 2007-12-21 | Wisconsin Alumni Research Foundation | Screening method for modulators of viral transcription or replication |
| GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
| WO2008133701A1 (en) | 2006-07-21 | 2008-11-06 | Medimmune, Llc. | Methods and compositions for increasing replication capacity of an influenza virus |
| CN104140958A (zh) | 2006-08-09 | 2014-11-12 | 米迪缪尼有限公司 | 流感血凝素和神经氨酸酶变体 |
| EP4585610A3 (en) | 2006-09-11 | 2025-09-24 | Seqirus UK Limited | Making influenza virus vaccines without using eggs |
| PT2121011E (pt) | 2006-12-06 | 2014-07-31 | Novartis Ag | Vacinas compreendendo um antigénio a partir de quatro estirpes do vírus da gripe |
| WO2008147496A2 (en) | 2007-05-04 | 2008-12-04 | Warf - Wisconsin Alumni Research Foundation | Neuraminidase-deficient live influenza vaccines |
| EP2674486A1 (en) | 2007-06-18 | 2013-12-18 | MedImmune, LLC | Influenza B viruses having alterations in the hemaglutinin polypeptide |
| US9474798B2 (en) | 2007-06-18 | 2016-10-25 | Wisconsin Alumni Research Foundation | Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
| EP2045323A1 (en) * | 2007-10-05 | 2009-04-08 | Avir Green Hills Biotechnology Research Development Trade Ag | Linear expression constructs for production of influenza virus particles |
| KR20100045437A (ko) | 2007-06-27 | 2010-05-03 | 노파르티스 아게 | 첨가물이 적은 인플루엔자 백신 |
| CN101497877B (zh) * | 2008-01-28 | 2012-09-05 | 河北摩百生物科技有限公司 | 流感全病毒减活疫苗重组体、其构建方法及应用 |
| JP5518041B2 (ja) | 2008-03-18 | 2014-06-11 | ノバルティス アーゲー | インフルエンザウイルスワクチン抗原の調製における改良 |
| RU2523587C2 (ru) | 2008-07-11 | 2014-07-20 | МЕДИММЬЮН, ЭлЭлСи | Варианты гемагглютинина и нейрамидазы вируса гриппа |
| EP2329845A4 (en) | 2008-08-18 | 2013-08-14 | Kitasato Daiichi Sankyo Vaccine Co Ltd | BIRD GRAPEVIRUS ANTIGEN AND BOOSTER IMMUNIZATION PROCEDURE FOR BIRD FLUID VACCINE IN COMBINATION WITH A MUCOSAL ADJUVAN WITH EFFICACY THROUGH ORAL ADMINISTRATION |
| EP2233568A1 (en) | 2009-03-19 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade AG | Novel method for generation of RNA virus |
| EA201171032A1 (ru) | 2009-02-10 | 2012-02-28 | Новартис Аг | Схемы лечения с помощью вакцины против гриппа, связанного с пандемическими штаммами |
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| EP2493912B1 (en) | 2009-10-26 | 2020-07-29 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in vero cells |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| CN103237890A (zh) | 2010-06-02 | 2013-08-07 | 巴克斯特保健股份有限公司 | 用于产生rna 病毒的方法和辅助病毒 |
| CN102220293B (zh) * | 2011-05-26 | 2012-12-19 | 中国农业科学院上海兽医研究所 | 犬流感重组病毒及其制备方法和应用 |
| JP2014527799A (ja) | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | 変異型ｐｂ２遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス |
| EP2751260A2 (en) | 2011-09-02 | 2014-07-09 | Westfälische Wilhelms-Universität Münster | Live attenuated influenza virus |
| EP2768528A1 (en) | 2011-10-20 | 2014-08-27 | Novartis AG | Adjuvanted influenza b virus vaccines for pediatric priming |
| GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
| WO2015009743A1 (en) | 2013-07-15 | 2015-01-22 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in mdck or vero cells or eggs |
| US10053671B2 (en) | 2014-06-20 | 2018-08-21 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| CN104450695B (zh) * | 2014-11-26 | 2017-08-25 | 扬州大学 | A型流感病毒基因pcr扩增引物及其快速克隆方法 |
| US10633422B2 (en) | 2015-06-01 | 2020-04-28 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA |
| AU2016274655B2 (en) * | 2015-06-10 | 2021-06-17 | NeoTrail Therapeutics, Inc. | HPV vaccines |
| US11013795B2 (en) | 2015-06-26 | 2021-05-25 | Seqirus UK Limited | Antigenically matched influenza vaccines |
| US9890363B2 (en) | 2015-07-06 | 2018-02-13 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication for vaccine development |
| KR102790570B1 (ko) | 2015-07-07 | 2025-04-04 | 세퀴러스 유케이 리미티드 | 인플루엔자 효능 검정 |
| US10494613B2 (en) | 2015-08-28 | 2019-12-03 | Wisconsin Alumni Research Foundation (Warf) | Generation of infectious influenza viruses from virus-like particles |
| US11197925B2 (en) | 2016-02-19 | 2021-12-14 | Wisconsin Alumni Research Foundation (Warf) | Influenza B virus replication for vaccine development |
| CA3074202A1 (en) * | 2017-08-28 | 2019-03-07 | Wisconsin Alumni Research Foundation | Nanocapsules for delivering ribonucleoproteins |
| WO2019084310A1 (en) | 2017-10-25 | 2019-05-02 | Yoshihiro Kawaoka | HAS RECOMBINANT INFLUENZA VIRUSES STABILIZED FOR EGG REPLICATION |
| CN107964035B (zh) * | 2017-12-06 | 2020-07-24 | 中国科学院微生物研究所 | 一种用于流感病毒的有限复制型黏膜免疫疫苗 |
| US12343390B2 (en) | 2018-08-07 | 2025-07-01 | Wisconsin Alumni Research Foundation (Warf) | Recombinant biologically contained filovirus vaccine |
| JP7655849B2 (ja) | 2018-08-20 | 2025-04-02 | ウィスコンシン アルムニ リサーチ ファンデイション | ヘマグルチニン（ｈａ）タンパク質内の非ドミナントエピトープに対する免疫応答を誘起するためのベクター |
| CN109097341B (zh) * | 2018-08-28 | 2021-09-24 | 青岛农业大学 | 一种同时表达ha和hef的复制缺陷型重组流感病毒 |
| EP3914295A2 (en) | 2019-01-23 | 2021-12-01 | Yoshihiro Kawaoka | Mutations that confer genetic stability to additional genes in influenza viruses |
| EP3921413A1 (en) | 2019-02-08 | 2021-12-15 | Wisconsin Alumni Research Foundation (WARF) | Humanized cell line |
| CN114929269A (zh) | 2019-05-01 | 2022-08-19 | 威斯康星校友研究基金会(Warf) | 用于疫苗开发的改进的流感病毒复制 |
| US11807872B2 (en) | 2019-08-27 | 2023-11-07 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| JP2023511444A (ja) | 2020-01-24 | 2023-03-17 | ウィスコンシン アルムニ リサーチ ファンデイション | 安定化されたｎａを有する組換えインフルエンザウイルス |
| WO2021195410A1 (en) | 2020-03-25 | 2021-09-30 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
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| US5840520A (en) * | 1989-08-28 | 1998-11-24 | Aviron | Recombinant negative strand RNA virus expression systems |
| US5658772A (en) | 1989-12-22 | 1997-08-19 | E. I. Du Pont De Nemours And Company | Site-specific recombination of DNA in plant cells |
| US5919676A (en) * | 1993-06-24 | 1999-07-06 | Advec, Inc. | Adenoviral vector system comprising Cre-loxP recombination |
| AU3760495A (en) * | 1994-09-30 | 1996-04-26 | Aviron | Chimeric Influenza Virus And Electroporation Method |
| EP0704533A1 (en) * | 1994-09-30 | 1996-04-03 | Bayer Ag | An attenuated vaccination virus, a method to make the virus and a pharmaceutical compositions comprising the virus |
| CN1200675A (zh) * | 1995-10-20 | 1998-12-02 | 耶路撒冷希伯来语大学依苏姆研究开发公司 | 流感疫苗 |
| US5994526A (en) * | 1996-06-21 | 1999-11-30 | Plant Genetic Systems | Gene expression in plants |
| EP1035209A1 (en) * | 1999-03-06 | 2000-09-13 | ARTEMIS Pharmaceuticals GmbH | Stable recombinant influenza viruses free of helper viruses |
| DE122008000035I1 (de) * | 1999-04-06 | 2009-05-20 | Wisconsin Alumni Res Found | Rekombinante influenzaviren zur vakzinherstellung und gentherapie |
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2000
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- 2000-04-05 PT PT00920151T patent/PT1185615E/pt unknown
- 2000-04-05 CN CN201010155623.8A patent/CN101851636B/zh not_active Expired - Lifetime
- 2000-04-05 ES ES00920151T patent/ES2290024T3/es not_active Expired - Lifetime
- 2000-04-05 DK DK00920151T patent/DK1185615T3/da active
- 2000-04-05 BR BRPI0009580A patent/BRPI0009580B8/pt not_active IP Right Cessation
- 2000-04-05 DE DE122008000061C patent/DE122008000061I1/de active Pending
- 2000-04-05 DE DE60035778T patent/DE60035778T2/de not_active Expired - Lifetime
- 2000-04-05 KR KR1020017012743A patent/KR100702275B1/ko not_active Expired - Lifetime
- 2000-04-05 AU AU40733/00A patent/AU4073300A/en not_active Abandoned
- 2000-04-05 JP JP2000609542A patent/JP5543048B2/ja not_active Expired - Lifetime
- 2000-04-05 AT AT07009953T patent/ATE525461T1/de active
- 2000-04-05 CN CN00807495XA patent/CN1350578B/zh not_active Expired - Lifetime
- 2000-04-05 EP EP07009953A patent/EP1820853B1/en not_active Expired - Lifetime
- 2000-04-05 EP EP00920151A patent/EP1185615B1/en not_active Expired - Lifetime
- 2000-04-05 EP EP10011896.7A patent/EP2345716B1/en not_active Expired - Lifetime
- 2000-04-05 ES ES07009953T patent/ES2373405T3/es not_active Expired - Lifetime
- 2000-04-05 IL IL14570200A patent/IL145702A0/xx unknown
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2001
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2007
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2008
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2011
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- 2011-07-26 DE DE201112100037 patent/DE122011100037I1/de active Pending
- 2011-07-26 FR FR11C0027C patent/FR11C0027I2/fr active Active
- 2011-12-12 CY CY20111101234T patent/CY1112140T1/el unknown
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2015
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2016
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