PT1706403E - Compostos de imidazo[4,5-c]piridina e métodos de tratamento antiviral - Google Patents

Info

Publication number

PT1706403E

PT1706403E PT04815224T PT04815224T PT1706403E PT 1706403 E PT1706403 E PT 1706403E PT 04815224 T PT04815224 T PT 04815224T PT 04815224 T PT04815224 T PT 04815224T PT 1706403 E PT1706403 E PT 1706403E

Authority

PT

Portugal

Prior art keywords

aryl

alkyl

quot

compound according

heterocycle

Prior art date

2003-12-22

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• 238000000034 method Methods 0.000 title claims abstract description 80
• 238000011282 treatment Methods 0.000 title claims abstract description 15
• 230000000840 anti-viral effect Effects 0.000 title claims description 11
• UBOOKRVGOBKDMM-UHFFFAOYSA-N 3h-imidazo[4,5-c]pyridine Chemical class C1=NC=C2NC=NC2=C1 UBOOKRVGOBKDMM-UHFFFAOYSA-N 0.000 title abstract description 6
• 150000001875 compounds Chemical class 0.000 claims abstract description 139
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• 238000011321 prophylaxis Methods 0.000 claims abstract description 3
• -1 -OH Chemical group 0.000 claims description 105
• 239000000203 mixture Substances 0.000 claims description 90
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• 229910052736 halogen Inorganic materials 0.000 claims description 25
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• 150000002367 halogens Chemical class 0.000 claims description 24
• 125000003545 alkoxy group Chemical group 0.000 claims description 21
• 125000004432 carbon atom Chemical group C* 0.000 claims description 21
• 229910052739 hydrogen Inorganic materials 0.000 claims description 21
• 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 claims description 20
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• 150000001413 amino acids Chemical class 0.000 claims description 19
• 125000004122 cyclic group Chemical group 0.000 claims description 19
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• 229910052757 nitrogen Inorganic materials 0.000 claims description 12
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 12
• 229910052717 sulfur Inorganic materials 0.000 claims description 12
• 125000000539 amino acid group Chemical group 0.000 claims description 11
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