PT1691814E - Agentes anti-inflamatórios - Google Patents
Agentes anti-inflamatórios Download PDFInfo
- Publication number
- PT1691814E PT1691814E PT04798708T PT04798708T PT1691814E PT 1691814 E PT1691814 E PT 1691814E PT 04798708 T PT04798708 T PT 04798708T PT 04798708 T PT04798708 T PT 04798708T PT 1691814 E PT1691814 E PT 1691814E
- Authority
- PT
- Portugal
- Prior art keywords
- caprolactam
- amino
- carbon atoms
- mmol
- compound
- Prior art date
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- 239000002260 anti-inflammatory agent Substances 0.000 title description 3
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- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 57
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- 125000004438 haloalkoxy group Chemical group 0.000 claims abstract description 6
- -1 amino caprolactam Chemical compound 0.000 claims description 38
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- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
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- Engineering & Computer Science (AREA)
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- Psychiatry (AREA)
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- Molecular Biology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0327775A GB0327775D0 (en) | 2003-12-01 | 2003-12-01 | Anti-inflammatory agents |
| GB0417436A GB0417436D0 (en) | 2004-08-05 | 2004-08-05 | Anti-inflammatory agents |
| GB0417734A GB0417734D0 (en) | 2004-08-10 | 2004-08-10 | Anti-Inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1691814E true PT1691814E (pt) | 2012-10-16 |
Family
ID=34657584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT04798708T PT1691814E (pt) | 2003-12-01 | 2004-11-30 | Agentes anti-inflamatórios |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20080227724A1 (enExample) |
| EP (2) | EP2279741A3 (enExample) |
| JP (1) | JP5248779B2 (enExample) |
| KR (1) | KR101228268B1 (enExample) |
| CN (1) | CN103393691A (enExample) |
| AR (1) | AR047730A1 (enExample) |
| CA (1) | CA2547651C (enExample) |
| CY (1) | CY1113171T1 (enExample) |
| DK (1) | DK1691814T3 (enExample) |
| ES (1) | ES2390272T3 (enExample) |
| IL (1) | IL175857A0 (enExample) |
| PL (1) | PL1691814T3 (enExample) |
| PT (1) | PT1691814E (enExample) |
| SI (1) | SI1691814T1 (enExample) |
| TW (1) | TWI356821B (enExample) |
| WO (1) | WO2005053702A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2418426A (en) | 2004-08-18 | 2006-03-29 | Univ Cambridge Tech | Alpha-(acylamino)-bicyclolactam derivatives for treatment of inflammatory disorders |
| AU2011226837B2 (en) * | 2004-09-02 | 2014-09-18 | Cambridge Enterprise Limited | Ligands for G-protein coupled receptors |
| GB2418427A (en) | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| GB0512238D0 (en) * | 2005-06-15 | 2005-07-27 | Univ Cambridge Tech | Anti-inflammatory agents |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| GB2455539B (en) * | 2007-12-12 | 2012-01-18 | Cambridge Entpr Ltd | Anti-inflammatory compositions and combinations |
| GB201009603D0 (en) * | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
| WO2013123290A1 (en) * | 2012-02-15 | 2013-08-22 | Anida Pharma Inc. | Methods of treating amyotrophic lateral sclerosis |
| ES3038130T3 (en) * | 2017-01-18 | 2025-10-09 | UNIV AUTòNOMA DE BARCELONA | Maresin for use in treating multiple sclerosis and amyotrophic lateral sclerosis |
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| GB327775A (en) | 1929-01-21 | 1930-04-17 | John Harry Grayson | Improvements in thermostats |
| NL37108C (enExample) | 1933-06-02 | |||
| US3697562A (en) * | 1969-10-17 | 1972-10-10 | Allied Chem | Novel fluorocarbon diamides |
| JPS53121781A (en) * | 1977-03-30 | 1978-10-24 | Torii Yakuhin Kk | Caprolactum derivatives |
| JPS625994A (ja) * | 1985-07-02 | 1987-01-12 | Toray Ind Inc | リジン誘導体の製造法 |
| EP0312157A3 (en) * | 1987-10-13 | 1990-07-25 | Merck & Co. Inc. | Tetrapeptide renin inhibitors having a novel c-terminal amino acid |
| JP3054738B2 (ja) * | 1988-07-22 | 2000-06-19 | 武田薬品工業株式会社 | チアゾロ［５，４―ｂ］アゼピン誘導体 |
| DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
| US5430022A (en) * | 1990-05-14 | 1995-07-04 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compound and its preparation |
| IT1247698B (it) * | 1990-06-21 | 1994-12-30 | Sigma Tau Ind Farmaceuti | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
| IT1254471B (it) * | 1992-02-27 | 1995-09-25 | Magis Farmaceutici | Derivati ammidici della (r)-glicerofosforil-(s)-serina o del suo diacil derivato, un processo per la loro preparazione e relative composizioni farmaceutiche per il potenziamento dei processi di apprendimento |
| US5821231A (en) * | 1993-12-06 | 1998-10-13 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using same |
| JP3506714B2 (ja) * | 1995-02-22 | 2004-03-15 | ノバルティス・アクチエンゲゼルシャフト | １−アリール−２−アシルアミノ−エタン化合物およびニューロキニン特にニューロキニン１アンタゴニストとしてのそれらの用途 |
| SG64939A1 (en) * | 1995-07-17 | 2002-02-19 | Mitsui Chemicals Inc | Olefin polymerization catalyst, process for preparing olefin polymer, and olefin polymer |
| JP3633060B2 (ja) | 1995-09-22 | 2005-03-30 | Ｊｓｒ株式会社 | 低結晶性エチレン系ランダム共重合体およびその組成物 |
| US5817757A (en) * | 1995-10-30 | 1998-10-06 | Merck & Co., Inc. | Inhibitors of peptide binding to MHO class II proteins |
| KR100490807B1 (ko) * | 1995-11-28 | 2005-10-14 | 세파론, 인코포레이티드 | 시스테인및세린프로테아제의d-아미노산함유억제제 |
| MY132550A (en) * | 1996-08-22 | 2007-10-31 | Novartis Ag | Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists |
| GB9621836D0 (en) * | 1996-10-19 | 1996-12-11 | Zeneca Ltd | Peptide compounds |
| IL158355A0 (en) * | 1996-12-23 | 2004-05-12 | Elan Pharm Inc | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS beta-AMYLOID PEPTIDE RELEASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US6989435B2 (en) | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US6506782B1 (en) * | 1998-02-27 | 2003-01-14 | Athena Neurosciences, Inc. | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| ATE317691T1 (de) * | 1998-03-20 | 2006-03-15 | Daiichi Asubio Pharma Co Ltd | Benzochinonderivate enthaltende hemmer von nf-kb |
| US6395282B1 (en) | 1998-04-16 | 2002-05-28 | University Of Rochester | Immunogenic conjugates of Gram-negative bacterial autoinducer molecules |
| HRP990246A2 (en) * | 1998-08-07 | 2000-06-30 | Du Pont Pharm Co | Succinoylamino benzodiazepines as inhibitors of a beta protein production |
| US6117870A (en) * | 1998-11-12 | 2000-09-12 | Fujirebio Kabushiki Kaisha | Cyclic amide derivatives |
| WO2000042071A2 (en) | 1999-01-12 | 2000-07-20 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US6344450B1 (en) * | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
| WO2001068655A2 (en) * | 2000-03-10 | 2001-09-20 | Ariad Pharmaceuticals, Inc. | Caprolactam derivatives and uses thereof |
-
2004
- 2004-11-30 PT PT04798708T patent/PT1691814E/pt unknown
- 2004-11-30 CN CN2013103149649A patent/CN103393691A/zh active Pending
- 2004-11-30 EP EP10011516A patent/EP2279741A3/en not_active Withdrawn
- 2004-11-30 TW TW093136880A patent/TWI356821B/zh not_active IP Right Cessation
- 2004-11-30 US US10/581,274 patent/US20080227724A1/en not_active Abandoned
- 2004-11-30 KR KR1020067010733A patent/KR101228268B1/ko not_active Expired - Fee Related
- 2004-11-30 DK DK04798708.6T patent/DK1691814T3/da active
- 2004-11-30 SI SI200431939T patent/SI1691814T1/sl unknown
- 2004-11-30 PL PL04798708T patent/PL1691814T3/pl unknown
- 2004-11-30 WO PCT/GB2004/005030 patent/WO2005053702A2/en not_active Ceased
- 2004-11-30 JP JP2006542002A patent/JP5248779B2/ja not_active Expired - Lifetime
- 2004-11-30 CA CA2547651A patent/CA2547651C/en not_active Expired - Fee Related
- 2004-11-30 ES ES04798708T patent/ES2390272T3/es not_active Expired - Lifetime
- 2004-11-30 EP EP04798708A patent/EP1691814B9/en not_active Expired - Lifetime
- 2004-12-01 AR ARP040104477A patent/AR047730A1/es not_active Application Discontinuation
-
2006
- 2006-05-23 IL IL175857A patent/IL175857A0/en unknown
-
2012
- 2012-10-04 CY CY20121100921T patent/CY1113171T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005053702A2 (en) | 2005-06-16 |
| KR20070018807A (ko) | 2007-02-14 |
| EP2279741A2 (en) | 2011-02-02 |
| SI1691814T1 (sl) | 2012-11-30 |
| CA2547651A1 (en) | 2005-06-16 |
| EP2279741A3 (en) | 2011-06-01 |
| HK1094680A1 (en) | 2007-04-04 |
| CY1113171T1 (el) | 2016-04-13 |
| AR047730A1 (es) | 2006-02-15 |
| US20080227724A1 (en) | 2008-09-18 |
| ES2390272T3 (es) | 2012-11-08 |
| WO2005053702A3 (en) | 2005-09-15 |
| PL1691814T3 (pl) | 2012-12-31 |
| EP1691814A2 (en) | 2006-08-23 |
| EP1691814B9 (en) | 2013-02-20 |
| JP2007512387A (ja) | 2007-05-17 |
| JP5248779B2 (ja) | 2013-07-31 |
| KR101228268B1 (ko) | 2013-01-31 |
| DK1691814T3 (da) | 2012-10-29 |
| TW200526585A (en) | 2005-08-16 |
| CN103393691A (zh) | 2013-11-20 |
| EP1691814B1 (en) | 2012-07-25 |
| IL175857A0 (en) | 2008-02-09 |
| CA2547651C (en) | 2015-06-23 |
| TWI356821B (en) | 2012-01-21 |
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