CA2547651C - Anti-inflammatory agents - Google Patents
Anti-inflammatory agents Download PDFInfo
- Publication number
- CA2547651C CA2547651C CA2547651A CA2547651A CA2547651C CA 2547651 C CA2547651 C CA 2547651C CA 2547651 A CA2547651 A CA 2547651A CA 2547651 A CA2547651 A CA 2547651A CA 2547651 C CA2547651 C CA 2547651C
- Authority
- CA
- Canada
- Prior art keywords
- caprolactam
- carbon atoms
- amino
- mmol
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0327775.3 | 2003-12-01 | ||
| GB0327775A GB0327775D0 (en) | 2003-12-01 | 2003-12-01 | Anti-inflammatory agents |
| GB0417436A GB0417436D0 (en) | 2004-08-05 | 2004-08-05 | Anti-inflammatory agents |
| GB0417436.3 | 2004-08-05 | ||
| GB0417734A GB0417734D0 (en) | 2004-08-10 | 2004-08-10 | Anti-Inflammatory agents |
| GB0417734.1 | 2004-08-10 | ||
| PCT/GB2004/005030 WO2005053702A2 (en) | 2003-12-01 | 2004-11-30 | Anti-inflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2547651A1 CA2547651A1 (en) | 2005-06-16 |
| CA2547651C true CA2547651C (en) | 2015-06-23 |
Family
ID=34657584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2547651A Expired - Fee Related CA2547651C (en) | 2003-12-01 | 2004-11-30 | Anti-inflammatory agents |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20080227724A1 (enExample) |
| EP (2) | EP1691814B9 (enExample) |
| JP (1) | JP5248779B2 (enExample) |
| KR (1) | KR101228268B1 (enExample) |
| CN (1) | CN103393691A (enExample) |
| AR (1) | AR047730A1 (enExample) |
| CA (1) | CA2547651C (enExample) |
| CY (1) | CY1113171T1 (enExample) |
| DK (1) | DK1691814T3 (enExample) |
| ES (1) | ES2390272T3 (enExample) |
| IL (1) | IL175857A0 (enExample) |
| PL (1) | PL1691814T3 (enExample) |
| PT (1) | PT1691814E (enExample) |
| SI (1) | SI1691814T1 (enExample) |
| TW (1) | TWI356821B (enExample) |
| WO (1) | WO2005053702A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2418426A (en) | 2004-08-18 | 2006-03-29 | Univ Cambridge Tech | Alpha-(acylamino)-bicyclolactam derivatives for treatment of inflammatory disorders |
| AU2011226837B2 (en) * | 2004-09-02 | 2014-09-18 | Cambridge Enterprise Limited | Ligands for G-protein coupled receptors |
| GB2418427A (en) * | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| GB0512238D0 (en) * | 2005-06-15 | 2005-07-27 | Univ Cambridge Tech | Anti-inflammatory agents |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| GB2455539B (en) * | 2007-12-12 | 2012-01-18 | Cambridge Entpr Ltd | Anti-inflammatory compositions and combinations |
| GB201009603D0 (en) | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
| JP6173352B2 (ja) * | 2012-02-15 | 2017-08-02 | アニダ ファーマ インコーポレイテッド | 筋萎縮性側索硬化症の治療方法 |
| EP3570827B1 (en) * | 2017-01-18 | 2025-06-25 | Universitat Autònoma de Barcelona | Maresin for use in treating multiple sclerosis and amyotrophic lateral sclerosis |
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| GB327775A (en) | 1929-01-21 | 1930-04-17 | John Harry Grayson | Improvements in thermostats |
| BE402700A (enExample) | 1933-06-02 | |||
| US3697562A (en) * | 1969-10-17 | 1972-10-10 | Allied Chem | Novel fluorocarbon diamides |
| JPS53121781A (en) * | 1977-03-30 | 1978-10-24 | Torii Yakuhin Kk | Caprolactum derivatives |
| JPS625994A (ja) * | 1985-07-02 | 1987-01-12 | Toray Ind Inc | リジン誘導体の製造法 |
| EP0312157A3 (en) * | 1987-10-13 | 1990-07-25 | Merck & Co. Inc. | Tetrapeptide renin inhibitors having a novel c-terminal amino acid |
| JP3054738B2 (ja) * | 1988-07-22 | 2000-06-19 | 武田薬品工業株式会社 | チアゾロ［５，４―ｂ］アゼピン誘導体 |
| DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
| US5430022A (en) * | 1990-05-14 | 1995-07-04 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compound and its preparation |
| IT1247698B (it) * | 1990-06-21 | 1994-12-30 | Sigma Tau Ind Farmaceuti | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
| IT1254471B (it) * | 1992-02-27 | 1995-09-25 | Magis Farmaceutici | Derivati ammidici della (r)-glicerofosforil-(s)-serina o del suo diacil derivato, un processo per la loro preparazione e relative composizioni farmaceutiche per il potenziamento dei processi di apprendimento |
| US5821231A (en) * | 1993-12-06 | 1998-10-13 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using same |
| WO1996026183A1 (en) * | 1995-02-22 | 1996-08-29 | Novartis Ag | 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists |
| SG64939A1 (en) * | 1995-07-17 | 2002-02-19 | Mitsui Chemicals Inc | Olefin polymerization catalyst, process for preparing olefin polymer, and olefin polymer |
| JP3633060B2 (ja) | 1995-09-22 | 2005-03-30 | Ｊｓｒ株式会社 | 低結晶性エチレン系ランダム共重合体およびその組成物 |
| US5817757A (en) * | 1995-10-30 | 1998-10-06 | Merck & Co., Inc. | Inhibitors of peptide binding to MHO class II proteins |
| ES2293651T3 (es) * | 1995-11-28 | 2008-03-16 | Cephalon, Inc. | Inhibidores de cisteina y serina proteasas derivados de aminoacidos d. |
| MY132550A (en) * | 1996-08-22 | 2007-10-31 | Novartis Ag | Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists |
| GB9621836D0 (en) * | 1996-10-19 | 1996-12-11 | Zeneca Ltd | Peptide compounds |
| DK0951466T3 (da) * | 1996-12-23 | 2009-03-16 | Elan Pharm Inc | Cycloalkyl-, lactam, lacton- og beslægtede forbindelser, farmaceutiske sammensætninger, der omfatter samme, og fremgangsmåder til inhibering af beta-amyloidpeptidfrigivelse og/eller dets syntese ved anvendelse af sådanne forbindelser |
| US6989435B2 (en) | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US6506782B1 (en) * | 1998-02-27 | 2003-01-14 | Athena Neurosciences, Inc. | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| CN1181817C (zh) * | 1998-03-20 | 2004-12-29 | 第一三得利制药株式会社 | 以苯基甲苯醌为有效成分的NF-kB抑制剂 |
| US6395282B1 (en) | 1998-04-16 | 2002-05-28 | University Of Rochester | Immunogenic conjugates of Gram-negative bacterial autoinducer molecules |
| HRP990246A2 (en) * | 1998-08-07 | 2000-06-30 | Du Pont Pharm Co | Succinoylamino benzodiazepines as inhibitors of a beta protein production |
| US6117870A (en) * | 1998-11-12 | 2000-09-12 | Fujirebio Kabushiki Kaisha | Cyclic amide derivatives |
| EP2386565A3 (en) | 1999-01-12 | 2013-11-20 | Cambridge Enterprise Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US6344450B1 (en) * | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
| AU2001243601A1 (en) * | 2000-03-10 | 2001-09-24 | Ariad Pharmaceuticals, Inc. | Caprolactam derivatives and uses thereof |
-
2004
- 2004-11-30 KR KR1020067010733A patent/KR101228268B1/ko not_active Expired - Fee Related
- 2004-11-30 US US10/581,274 patent/US20080227724A1/en not_active Abandoned
- 2004-11-30 EP EP04798708A patent/EP1691814B9/en not_active Expired - Lifetime
- 2004-11-30 WO PCT/GB2004/005030 patent/WO2005053702A2/en not_active Ceased
- 2004-11-30 SI SI200431939T patent/SI1691814T1/sl unknown
- 2004-11-30 JP JP2006542002A patent/JP5248779B2/ja not_active Expired - Lifetime
- 2004-11-30 ES ES04798708T patent/ES2390272T3/es not_active Expired - Lifetime
- 2004-11-30 PT PT04798708T patent/PT1691814E/pt unknown
- 2004-11-30 EP EP10011516A patent/EP2279741A3/en not_active Withdrawn
- 2004-11-30 CN CN2013103149649A patent/CN103393691A/zh active Pending
- 2004-11-30 TW TW093136880A patent/TWI356821B/zh not_active IP Right Cessation
- 2004-11-30 PL PL04798708T patent/PL1691814T3/pl unknown
- 2004-11-30 DK DK04798708.6T patent/DK1691814T3/da active
- 2004-11-30 CA CA2547651A patent/CA2547651C/en not_active Expired - Fee Related
- 2004-12-01 AR ARP040104477A patent/AR047730A1/es not_active Application Discontinuation
-
2006
- 2006-05-23 IL IL175857A patent/IL175857A0/en unknown
-
2012
- 2012-10-04 CY CY20121100921T patent/CY1113171T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TWI356821B (en) | 2012-01-21 |
| WO2005053702A2 (en) | 2005-06-16 |
| HK1094680A1 (en) | 2007-04-04 |
| WO2005053702A3 (en) | 2005-09-15 |
| US20080227724A1 (en) | 2008-09-18 |
| EP2279741A2 (en) | 2011-02-02 |
| EP1691814B1 (en) | 2012-07-25 |
| SI1691814T1 (sl) | 2012-11-30 |
| EP2279741A3 (en) | 2011-06-01 |
| PT1691814E (pt) | 2012-10-16 |
| JP2007512387A (ja) | 2007-05-17 |
| CY1113171T1 (el) | 2016-04-13 |
| JP5248779B2 (ja) | 2013-07-31 |
| EP1691814A2 (en) | 2006-08-23 |
| KR20070018807A (ko) | 2007-02-14 |
| KR101228268B1 (ko) | 2013-01-31 |
| AR047730A1 (es) | 2006-02-15 |
| EP1691814B9 (en) | 2013-02-20 |
| CA2547651A1 (en) | 2005-06-16 |
| CN103393691A (zh) | 2013-11-20 |
| DK1691814T3 (da) | 2012-10-29 |
| ES2390272T3 (es) | 2012-11-08 |
| IL175857A0 (en) | 2008-02-09 |
| TW200526585A (en) | 2005-08-16 |
| PL1691814T3 (pl) | 2012-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20161130 |