IT1247698B - 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti - Google Patents
1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali compostiInfo
- Publication number
- IT1247698B IT1247698B IT04808790A IT4808790A IT1247698B IT 1247698 B IT1247698 B IT 1247698B IT 04808790 A IT04808790 A IT 04808790A IT 4808790 A IT4808790 A IT 4808790A IT 1247698 B IT1247698 B IT 1247698B
- Authority
- IT
- Italy
- Prior art keywords
- memory
- pharmaceutical compositions
- caprolattami
- alchil
- acylamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT04808790A IT1247698B (it) | 1990-06-21 | 1990-06-21 | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
EP91830276A EP0462949B1 (en) | 1990-06-21 | 1991-06-20 | 1-alkyl-3-(acylamino)-epsilon-caprolactames as enhancers of learning and memory and pharmaceutical compositions containing same |
DE69115135T DE69115135T2 (de) | 1990-06-21 | 1991-06-20 | 1-Alkyl-3-(Acylamino)-Epsilon-Caprolactame zur Verbesserung der Lernfähigkeit und des Gedächtnisses und diese enthaltende pharmazeutische Zubereitungen. |
AT91830276T ATE131159T1 (de) | 1990-06-21 | 1991-06-20 | 1-alkyl-3-(acylamino)-epsilon-caprolactame zur verbesserung der lernfähigkeit und des gedächtnisses und diese enthaltende pharmazeutische zubereitungen. |
DK91830276.1T DK0462949T3 (da) | 1990-06-21 | 1991-06-20 | 3-(Acylamino- og 1-alkyl-3-(acylamino)-epsilon-caprolactamer til forøgelse af indlæring og hukommelse og farmaceutiske præparater indeholdende disse |
ES91830276T ES2081463T3 (es) | 1990-06-21 | 1991-06-20 | 1-alquil-3-(acilamino)-epsilon-caprolactamas como mejoradores del aprendimiento y memoria y composiciones farmaceuticas que las contienen. |
JP3150301A JPH04230266A (ja) | 1990-06-21 | 1991-06-21 | 学習および記憶力増進剤としての1−アルキル−3−(アシルアミノ)−ε−カプロラクタム類およびそれらを含む医薬組成物 |
US07/718,645 US5155102A (en) | 1990-06-21 | 1991-06-21 | 1-alkyl-3-(acylamino)-ε-caprolactames as enhancers of learning and memory and pharmaceutical compositions containing same |
GR960400482T GR3019076T3 (en) | 1990-06-21 | 1996-02-22 | 1-alkyl-3-(acylamino)-epsilon-caprolactames as enhancers of learning and memory and pharmaceutical compositions containing same. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT04808790A IT1247698B (it) | 1990-06-21 | 1990-06-21 | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9048087A0 IT9048087A0 (it) | 1990-06-21 |
IT9048087A1 IT9048087A1 (it) | 1991-12-21 |
IT1247698B true IT1247698B (it) | 1994-12-30 |
Family
ID=11264450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT04808790A IT1247698B (it) | 1990-06-21 | 1990-06-21 | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
Country Status (9)
Country | Link |
---|---|
US (1) | US5155102A (it) |
EP (1) | EP0462949B1 (it) |
JP (1) | JPH04230266A (it) |
AT (1) | ATE131159T1 (it) |
DE (1) | DE69115135T2 (it) |
DK (1) | DK0462949T3 (it) |
ES (1) | ES2081463T3 (it) |
GR (1) | GR3019076T3 (it) |
IT (1) | IT1247698B (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1175405A4 (en) * | 1999-02-09 | 2002-05-15 | Bristol Myers Squibb Co | LACTAM INHIBITORS OF FACTOR Xa AND ASSOCIATED METHOD |
WO2000047207A1 (en) | 1999-02-09 | 2000-08-17 | Bristol-Myers Squibb Company | LACTAM INHIBITORS OF FXa AND METHOD |
US6344450B1 (en) | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
US6511973B2 (en) | 2000-08-02 | 2003-01-28 | Bristol-Myers Squibb Co. | Lactam inhibitors of FXa and method |
JP5248779B2 (ja) * | 2003-12-01 | 2013-07-31 | ケンブリッジ エンタープライズ リミティド | 抗炎症剤 |
CN101090885A (zh) * | 2004-02-23 | 2007-12-19 | 塔夫茨大学信托人 | 作为构象限定的肽模拟物抑制剂的内酰胺类化合物 |
GB2418425B (en) * | 2004-08-11 | 2008-09-03 | Univ Cambridge Tech | Anti-inflammatory agents |
GB201009603D0 (en) | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1231921B (it) * | 1989-06-12 | 1992-01-15 | Sigma Tau Ind Farmaceuti | 1-acil-2-pirrolidoni quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
IT1231477B (it) * | 1989-07-12 | 1991-12-07 | Sigma Tau Ind Farmaceuti | (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
-
1990
- 1990-06-21 IT IT04808790A patent/IT1247698B/it active IP Right Grant
-
1991
- 1991-06-20 EP EP91830276A patent/EP0462949B1/en not_active Expired - Lifetime
- 1991-06-20 DK DK91830276.1T patent/DK0462949T3/da active
- 1991-06-20 DE DE69115135T patent/DE69115135T2/de not_active Expired - Fee Related
- 1991-06-20 AT AT91830276T patent/ATE131159T1/de not_active IP Right Cessation
- 1991-06-20 ES ES91830276T patent/ES2081463T3/es not_active Expired - Lifetime
- 1991-06-21 JP JP3150301A patent/JPH04230266A/ja active Pending
- 1991-06-21 US US07/718,645 patent/US5155102A/en not_active Expired - Fee Related
-
1996
- 1996-02-22 GR GR960400482T patent/GR3019076T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5155102A (en) | 1992-10-13 |
ATE131159T1 (de) | 1995-12-15 |
DE69115135T2 (de) | 1996-05-09 |
EP0462949A1 (en) | 1991-12-27 |
IT9048087A1 (it) | 1991-12-21 |
ES2081463T3 (es) | 1996-03-16 |
JPH04230266A (ja) | 1992-08-19 |
IT9048087A0 (it) | 1990-06-21 |
EP0462949B1 (en) | 1995-12-06 |
GR3019076T3 (en) | 1996-05-31 |
DK0462949T3 (da) | 1996-02-05 |
DE69115135D1 (de) | 1996-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940526 |