GB1450793A - Pharmaceutical compositions containing dioxo-isoquinoline derivatives - Google Patents

Pharmaceutical compositions containing dioxo-isoquinoline derivatives

Info

Publication number
GB1450793A
GB1450793A GB3638873A GB3638873A GB1450793A GB 1450793 A GB1450793 A GB 1450793A GB 3638873 A GB3638873 A GB 3638873A GB 3638873 A GB3638873 A GB 3638873A GB 1450793 A GB1450793 A GB 1450793A
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical compositions
compositions containing
isoquinoline derivatives
dioxo
containing dioxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3638873A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of GB1450793A publication Critical patent/GB1450793A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/14—Monocyclic dicarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Process for the preparation of novel acid amides of the formula I <IMAGE> in which R1 to R3 which are identical or different, denote hydrogen or alkyl having 1 to 3 carbon atoms. The novel compounds are distinguished by useful pharmacological properties, in particular by muscle-relaxant, sedating, antiarrhythmic and anticonvulsive actions. They are prepared, starting from the corresponding isochromanones or the corresponding dicarboxylic acids, by reaction with suitably substituted glycinamides or their acid addition salts.
GB3638873A 1972-08-01 1973-07-31 Pharmaceutical compositions containing dioxo-isoquinoline derivatives Expired GB1450793A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2237770A DE2237770A1 (en) 1972-08-01 1972-08-01 NEW ACID AMID

Publications (1)

Publication Number Publication Date
GB1450793A true GB1450793A (en) 1976-09-29

Family

ID=5852334

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3638873A Expired GB1450793A (en) 1972-08-01 1973-07-31 Pharmaceutical compositions containing dioxo-isoquinoline derivatives

Country Status (12)

Country Link
JP (1) JPS558973B2 (en)
AT (2) AT329059B (en)
AU (1) AU476552B2 (en)
BE (1) BE803086A (en)
CH (6) CH615918A5 (en)
DE (1) DE2237770A1 (en)
DK (1) DK137008C (en)
ES (6) ES417443A1 (en)
FI (1) FI52218C (en)
FR (1) FR2194435A1 (en)
GB (1) GB1450793A (en)
NL (1) NL7310562A (en)

Also Published As

Publication number Publication date
CH611887A5 (en) 1979-06-29
ES422932A1 (en) 1976-06-16
ES422933A1 (en) 1976-06-16
JPS558973B2 (en) 1980-03-07
ES422929A1 (en) 1976-06-16
ATA673773A (en) 1975-07-15
CH612184A5 (en) 1979-07-13
DK137008C (en) 1978-05-22
DK137008B (en) 1978-01-02
CH615423A5 (en) 1980-01-31
AU476552B2 (en) 1976-09-30
FI52218C (en) 1977-07-11
JPS4980080A (en) 1974-08-02
FI52218B (en) 1977-03-31
CH615918A5 (en) 1980-02-29
AT329059B (en) 1976-04-26
AU5873573A (en) 1975-02-06
ATA225975A (en) 1975-07-15
ES422931A1 (en) 1976-06-16
ES422930A1 (en) 1976-06-16
AT329060B (en) 1976-04-26
CH611888A5 (en) 1979-06-29
FR2194435A1 (en) 1974-03-01
CH611280A5 (en) 1979-05-31
NL7310562A (en) 1974-02-05
ES417443A1 (en) 1976-03-16
DE2237770A1 (en) 1974-02-14
BE803086A (en) 1974-01-31

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee