ES422932A1 - Pharmaceutical compositions containing dioxo-isoquinoline derivatives - Google Patents

Pharmaceutical compositions containing dioxo-isoquinoline derivatives

Info

Publication number
ES422932A1
ES422932A1 ES422932A ES422932A ES422932A1 ES 422932 A1 ES422932 A1 ES 422932A1 ES 422932 A ES422932 A ES 422932A ES 422932 A ES422932 A ES 422932A ES 422932 A1 ES422932 A1 ES 422932A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
compositions containing
isoquinoline derivatives
dioxo
containing dioxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES422932A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES422932A1 publication Critical patent/ES422932A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/14Monocyclic dicarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

Process for the preparation of novel acid amides of the formula I < IMAGE > in which R1 to R3 which are identical or different, denote hydrogen or alkyl having 1 to 3 carbon atoms. The novel compounds are distinguished by useful pharmacological properties, in particular by muscle-relaxant, sedating, antiarrhythmic and anticonvulsive actions. They are prepared, starting from the corresponding isochromanones or the corresponding dicarboxylic acids, by reaction with suitably substituted glycinamides or their acid addition salts.
ES422932A 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives Expired ES422932A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2237770A DE2237770A1 (en) 1972-08-01 1972-08-01 NEW ACID AMID

Publications (1)

Publication Number Publication Date
ES422932A1 true ES422932A1 (en) 1976-06-16

Family

ID=5852334

Family Applications (6)

Application Number Title Priority Date Filing Date
ES417443A Expired ES417443A1 (en) 1972-08-01 1973-07-31 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422930A Expired ES422930A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422933A Expired ES422933A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422932A Expired ES422932A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422931A Expired ES422931A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422929A Expired ES422929A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES417443A Expired ES417443A1 (en) 1972-08-01 1973-07-31 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422930A Expired ES422930A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422933A Expired ES422933A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES422931A Expired ES422931A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives
ES422929A Expired ES422929A1 (en) 1972-08-01 1974-02-05 Pharmaceutical compositions containing dioxo-isoquinoline derivatives

Country Status (12)

Country Link
JP (1) JPS558973B2 (en)
AT (2) AT329059B (en)
AU (1) AU476552B2 (en)
BE (1) BE803086A (en)
CH (6) CH615918A5 (en)
DE (1) DE2237770A1 (en)
DK (1) DK137008C (en)
ES (6) ES417443A1 (en)
FI (1) FI52218C (en)
FR (1) FR2194435A1 (en)
GB (1) GB1450793A (en)
NL (1) NL7310562A (en)

Also Published As

Publication number Publication date
BE803086A (en) 1974-01-31
ES422933A1 (en) 1976-06-16
CH611888A5 (en) 1979-06-29
AT329059B (en) 1976-04-26
DK137008B (en) 1978-01-02
ES422929A1 (en) 1976-06-16
FR2194435A1 (en) 1974-03-01
CH612184A5 (en) 1979-07-13
GB1450793A (en) 1976-09-29
NL7310562A (en) 1974-02-05
CH611887A5 (en) 1979-06-29
JPS558973B2 (en) 1980-03-07
ES422931A1 (en) 1976-06-16
ES422930A1 (en) 1976-06-16
DK137008C (en) 1978-05-22
AT329060B (en) 1976-04-26
FI52218B (en) 1977-03-31
DE2237770A1 (en) 1974-02-14
AU476552B2 (en) 1976-09-30
AU5873573A (en) 1975-02-06
ATA225975A (en) 1975-07-15
FI52218C (en) 1977-07-11
ES417443A1 (en) 1976-03-16
CH611280A5 (en) 1979-05-31
ATA673773A (en) 1975-07-15
JPS4980080A (en) 1974-08-02
CH615423A5 (en) 1980-01-31
CH615918A5 (en) 1980-02-29

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