IL42380A - Preparation of 2-alkoxy (or alkenyloxy)-4,5-substituted aminoalkyl benzamides - Google Patents
Preparation of 2-alkoxy (or alkenyloxy)-4,5-substituted aminoalkyl benzamidesInfo
- Publication number
- IL42380A IL42380A IL42380A IL4238073A IL42380A IL 42380 A IL42380 A IL 42380A IL 42380 A IL42380 A IL 42380A IL 4238073 A IL4238073 A IL 4238073A IL 42380 A IL42380 A IL 42380A
- Authority
- IL
- Israel
- Prior art keywords
- radical
- alkyl
- group
- general formula
- vith
- Prior art date
Links
- -1 aminoalkyl benzamides Chemical class 0.000 title claims 2
- 229940054066 benzamide antipsychotics Drugs 0.000 title claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000005711 Benzoic acid Substances 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000004442 acylamino group Chemical group 0.000 claims 1
- 125000001931 aliphatic group Chemical group 0.000 claims 1
- 125000003302 alkenyloxy group Chemical group 0.000 claims 1
- 230000002152 alkylating effect Effects 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 150000003936 benzamides Chemical class 0.000 claims 1
- 235000010233 benzoic acid Nutrition 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 150000004985 diamines Chemical class 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (1)
1. 3 L A I novel method of preparing substituted corresponding to the following general formula their salts of addition vith pharmaceutically orga and their quaternary salts produced by reacting said benzamides vith an aliphatic or aronatic alkylating in can be a hydrogen atom or a methyl Z can be an alkyl radical or an alkenyl radical 1 to X can be a hydrogen a nitro or carboxylic acylamino Y can be a hydrogen a halogen or a group in v is an amino group or a group or a o group or an alkyl group having from 1 to carbon atoms or a halogencalkyl n can be an integer eaual to or less than can be either a radical of the and identical or different alkyl groups of nolecular veight vhich vith nitrogen can form a saturated heterocyclic or a heterocyclic radical having the formula in E can be an alkyl radical or an radical iron 1 to m can be an integer equal to or less than or alkenyloxy characterised by the reaction of benzoic acid having the general formula in which X and Y are as defined with an ester of haloformic acid having the general formula in which is a halogen atom and B is an alkyl the alkyl carboxylic acid anhydride formed being reacted with a diamine having the general formula in vhich n and A are as defined to form the expected benzaaide For the Applicants insufficientOCRQuality
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7219804A FR2193577A1 (en) | 1972-06-01 | 1972-06-01 | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics |
| FR7219803A FR2187310A1 (en) | 1972-06-01 | 1972-06-01 | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics |
| FR7221307A FR2187323A1 (en) | 1972-06-12 | 1972-06-12 | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics |
| FR7312045A FR2224447A1 (en) | 1973-04-03 | 1973-04-03 | N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42380A0 IL42380A0 (en) | 1973-07-30 |
| IL42380A true IL42380A (en) | 1976-12-31 |
Family
ID=27446178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL42380A IL42380A (en) | 1972-06-01 | 1973-05-29 | Preparation of 2-alkoxy (or alkenyloxy)-4,5-substituted aminoalkyl benzamides |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5648507B2 (en) |
| AU (1) | AU472570B2 (en) |
| BG (1) | BG21213A3 (en) |
| CA (1) | CA986927A (en) |
| CH (1) | CH585699A5 (en) |
| CS (1) | CS174885B2 (en) |
| DD (1) | DD107264A5 (en) |
| DE (1) | DE2327192C2 (en) |
| GB (1) | GB1394563A (en) |
| HU (1) | HU167379B (en) |
| IE (1) | IE38116B1 (en) |
| IL (1) | IL42380A (en) |
| LU (1) | LU67702A1 (en) |
| MC (1) | MC965A1 (en) |
| PH (2) | PH10249A (en) |
| YU (1) | YU39069B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH605793A5 (en) * | 1974-03-05 | 1978-10-13 | Soc Et Scient Et Ind | Process for the preparation of new substituted N-(1benzylpyrrollidinil 2-alkyl) benzamides |
| GB1513631A (en) * | 1976-02-17 | 1978-06-07 | Gallardo Antonio Sa | Piperidine derivatives |
| PT655996E (en) * | 1992-08-19 | 2002-04-29 | Pfizer | SUBSTITUTED BENZYLAMINS CONTAINING NON-AROMATIC HETEROCYCLICS CONTAINING NITROGEN |
-
1973
- 1973-05-28 DE DE2327192A patent/DE2327192C2/en not_active Expired
- 1973-05-28 CS CS3835A patent/CS174885B2/cs unknown
- 1973-05-28 BG BG023727A patent/BG21213A3/en unknown
- 1973-05-28 PH PH14660*A patent/PH10249A/en unknown
- 1973-05-28 MC MC1045A patent/MC965A1/en unknown
- 1973-05-28 HU HUSO1079A patent/HU167379B/hu unknown
- 1973-05-29 JP JP6076473A patent/JPS5648507B2/ja not_active Expired
- 1973-05-29 YU YU01420/73A patent/YU39069B/en unknown
- 1973-05-29 IL IL42380A patent/IL42380A/en unknown
- 1973-05-29 GB GB2540273A patent/GB1394563A/en not_active Expired
- 1973-05-30 CH CH785873A patent/CH585699A5/xx not_active IP Right Cessation
- 1973-05-30 LU LU67702A patent/LU67702A1/xx unknown
- 1973-05-30 AU AU56306/73A patent/AU472570B2/en not_active Expired
- 1973-05-31 IE IE872/73A patent/IE38116B1/en unknown
- 1973-05-31 CA CA172,906A patent/CA986927A/en not_active Expired
- 1973-05-31 DD DD171220A patent/DD107264A5/xx unknown
-
1975
- 1975-05-27 PH PH17195A patent/PH11617A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4985037A (en) | 1974-08-15 |
| JPS5648507B2 (en) | 1981-11-16 |
| PH11617A (en) | 1978-04-12 |
| PH10249A (en) | 1976-10-14 |
| BG21213A3 (en) | 1976-03-20 |
| AU5630673A (en) | 1974-12-05 |
| LU67702A1 (en) | 1974-07-05 |
| IL42380A0 (en) | 1973-07-30 |
| YU39069B (en) | 1984-04-30 |
| IE38116B1 (en) | 1978-01-04 |
| AU472570B2 (en) | 1976-05-27 |
| CA986927A (en) | 1976-04-06 |
| HU167379B (en) | 1975-09-27 |
| DE2327192C2 (en) | 1983-02-17 |
| YU142073A (en) | 1982-02-28 |
| DD107264A5 (en) | 1974-07-20 |
| IE38116L (en) | 1973-12-01 |
| MC965A1 (en) | 1974-02-01 |
| GB1394563A (en) | 1975-05-21 |
| CS174885B2 (en) | 1977-04-29 |
| CH585699A5 (en) | 1977-03-15 |
| DE2327192A1 (en) | 1973-12-13 |
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