ES334530A1 - N-substituted amides of -acylamino-acrylic acids - Google Patents

N-substituted amides of -acylamino-acrylic acids

Info

Publication number
ES334530A1
ES334530A1 ES334530A ES334530A ES334530A1 ES 334530 A1 ES334530 A1 ES 334530A1 ES 334530 A ES334530 A ES 334530A ES 334530 A ES334530 A ES 334530A ES 334530 A1 ES334530 A1 ES 334530A1
Authority
ES
Spain
Prior art keywords
acylamino
reacting
acid
acrylic acids
substituted amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES334530A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scheurich Pharmwerk E GmbH
Original Assignee
Scheurich Pharmwerk E GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scheurich Pharmwerk E GmbH filed Critical Scheurich Pharmwerk E GmbH
Publication of ES334530A1 publication Critical patent/ES334530A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Abstract

Novel compounds of formula <FORM:1113569/C2/1> wherein R1 and R2 represent hydrogen atoms or unsubstituted or substituted alkyl, aryl or aralkyl groups, and R3 represents a tertiary amine linked through an alkylene group, and acid addition salts thereof, are prepared by reacting an azlactone of an a -acylamino-acrylic acid with an amine R3NH2, or by reacting an ester of the appropriate a -acylaminoacrylic acid with diamine, and, in either case, if desired, reacting the base obtained with an acid in the presence of a solvent.
ES334530A 1965-12-20 1966-12-15 N-substituted amides of -acylamino-acrylic acids Expired ES334530A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DESC038215 1965-12-20
DESC039618 1966-10-03

Publications (1)

Publication Number Publication Date
ES334530A1 true ES334530A1 (en) 1968-02-16

Family

ID=25993340

Family Applications (1)

Application Number Title Priority Date Filing Date
ES334530A Expired ES334530A1 (en) 1965-12-20 1966-12-15 N-substituted amides of -acylamino-acrylic acids

Country Status (7)

Country Link
AT (1) AT277195B (en)
BE (1) BE690536A (en)
DE (2) DE1493184A1 (en)
ES (1) ES334530A1 (en)
FR (1) FR1511631A (en)
GB (1) GB1113569A (en)
NL (1) NL6617752A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI396543B (en) 2005-05-12 2013-05-21 Sankyo Co Substituted acrylamide derivatives and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
NL6617752A (en) 1967-06-21
DE1620463A1 (en) 1970-04-09
FR1511631A (en) 1968-02-02
DE1493184A1 (en) 1969-04-24
GB1113569A (en) 1968-05-15
AT277195B (en) 1969-12-10
BE690536A (en) 1967-06-01

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