ES463557A2 - N-(4-piperidyl)-benzamides and pharmaceutical compositions containing them - Google Patents
N-(4-piperidyl)-benzamides and pharmaceutical compositions containing themInfo
- Publication number
- ES463557A2 ES463557A2 ES463557A ES463557A ES463557A2 ES 463557 A2 ES463557 A2 ES 463557A2 ES 463557 A ES463557 A ES 463557A ES 463557 A ES463557 A ES 463557A ES 463557 A2 ES463557 A2 ES 463557A2
- Authority
- ES
- Spain
- Prior art keywords
- benzamides
- piperidyl
- pharmaceutical compositions
- compositions containing
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JMQDNLCNCDSHNC-UHFFFAOYSA-N n-piperidin-4-ylbenzamide Chemical class C=1C=CC=CC=1C(=O)NC1CCNCC1 JMQDNLCNCDSHNC-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000008430 aromatic amides Chemical class 0.000 abstract 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Natural products OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
An aromatic amide N-substituted by heterocyclic groups of general formula < IMAGE > is obtained by reaction of the substituted benzoic acid of formula < IMAGE > with a compound of formula < IMAGE > in which the radicals R1, R2, R3 and the letters x, y and z correspond to the definition given in Claim 1. The N-substituted aromatic amide thus obtained has the property of antagonising the effects of dopamine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4464976A GB1593851A (en) | 1976-10-27 | 1976-10-27 | N-(4-piperidyl)-benzamides and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES463557A2 true ES463557A2 (en) | 1978-11-16 |
Family
ID=10434204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES463557A Expired ES463557A2 (en) | 1976-10-27 | 1977-10-26 | N-(4-piperidyl)-benzamides and pharmaceutical compositions containing them |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5392783A (en) |
| BE (1) | BE860139R (en) |
| CA (1) | CA1085855A (en) |
| CH (1) | CH625219A5 (en) |
| ES (1) | ES463557A2 (en) |
| FR (1) | FR2378762A2 (en) |
| GB (1) | GB1593851A (en) |
| NL (1) | NL7711690A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1057101A (en) * | 1999-11-17 | 2001-05-30 | Kissei Pharmaceutical Co. Ltd. | Hydroxyethoxybenzamide derivatives and drugs containing the same |
| TWI295669B (en) | 2002-10-30 | 2008-04-11 | Theravance Inc | Substituted 4-amino-1-(pyridylmethyl) piperidine and related compounds |
| JP2007524641A (en) | 2003-07-11 | 2007-08-30 | セラヴァンス, インコーポレーテッド | Substituted 4-amino-1-benzylpiperidine compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5916M (en) * | 1966-01-21 | 1968-05-06 | ||
| GB1345872A (en) * | 1970-09-03 | 1974-02-06 | Wyeth John & Brother Ltd | Amino-and acylamino-pyridine and hydropyridine derivatives |
-
1976
- 1976-10-27 GB GB4464976A patent/GB1593851A/en not_active Expired
-
1977
- 1977-10-25 NL NL7711690A patent/NL7711690A/en not_active Application Discontinuation
- 1977-10-25 CH CH1295177A patent/CH625219A5/en not_active IP Right Cessation
- 1977-10-26 BE BE182086A patent/BE860139R/en not_active IP Right Cessation
- 1977-10-26 ES ES463557A patent/ES463557A2/en not_active Expired
- 1977-10-26 FR FR7733111A patent/FR2378762A2/en active Granted
- 1977-10-26 CA CA289,550A patent/CA1085855A/en not_active Expired
- 1977-10-27 JP JP12915777A patent/JPS5392783A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5392783A (en) | 1978-08-15 |
| BE860139R (en) | 1978-02-15 |
| FR2378762A2 (en) | 1978-08-25 |
| CA1085855A (en) | 1980-09-16 |
| NL7711690A (en) | 1978-05-02 |
| CH625219A5 (en) | 1981-09-15 |
| FR2378762B2 (en) | 1980-09-12 |
| GB1593851A (en) | 1981-07-22 |
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