ZA8837B - N-(1h-indol-4-yl)benzamide derivatives and also their salts,their application by way of medicinal products and the compositions containing them - Google Patents

N-(1h-indol-4-yl)benzamide derivatives and also their salts,their application by way of medicinal products and the compositions containing them

Info

Publication number
ZA8837B
ZA8837B ZA8837A ZA8837A ZA8837B ZA 8837 B ZA8837 B ZA 8837B ZA 8837 A ZA8837 A ZA 8837A ZA 8837 A ZA8837 A ZA 8837A ZA 8837 B ZA8837 B ZA 8837B
Authority
ZA
South Africa
Prior art keywords
salts
indol
way
application
compositions containing
Prior art date
Application number
ZA8837A
Inventor
Francois Clemence
Clemence Francois
Jacques Guillaume
Guillaume Jacques
Gilles Hamon
Hamon Gilles
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA8837B publication Critical patent/ZA8837B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Products of formula (I): <IMAGE> in which one of the substituents X and Y denotes alkyl (C1-C5), alkoxy (C1-C3), chlorine, bromine, iodine, nitro or amino optionally substituted by an aliphatic acyl (C2-C5) or 2 alkyls (C1-C5) and the other substituent denotes a hydrogen, it being understood that Y does not denote methoxy and X chlorine, and their addition salts with acids. The products (I) are endowed with antiarrhythmic properties and some have anticalcic properties.
ZA8837A 1987-01-09 1988-01-05 N-(1h-indol-4-yl)benzamide derivatives and also their salts,their application by way of medicinal products and the compositions containing them ZA8837B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8700151A FR2609464B1 (en) 1987-01-09 1987-01-09 NOVEL N- (1H-INDOL 4-YL) BENZAMIDE DERIVATIVES AND THEIR SALTS, THEIR USE AS MEDICAMENTS, AND THE COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
ZA8837B true ZA8837B (en) 1989-03-29

Family

ID=9346770

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8837A ZA8837B (en) 1987-01-09 1988-01-05 N-(1h-indol-4-yl)benzamide derivatives and also their salts,their application by way of medicinal products and the compositions containing them

Country Status (14)

Country Link
EP (1) EP0275221B1 (en)
JP (1) JPS63188664A (en)
KR (1) KR880008988A (en)
AT (1) ATE62673T1 (en)
AU (1) AU619728B2 (en)
DE (1) DE3862380D1 (en)
DK (1) DK168377B1 (en)
ES (1) ES2029033T3 (en)
FI (1) FI85140C (en)
FR (1) FR2609464B1 (en)
GR (1) GR3002185T3 (en)
HU (1) HU201910B (en)
IE (1) IE60779B1 (en)
ZA (1) ZA8837B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234942A (en) * 1984-10-19 1993-08-10 Ici Americas Inc. Heterocyclic amides and leucotriene antagonistic use thereof
DE4119611A1 (en) * 1991-06-14 1992-12-17 Bayer Ag AGENTS FOR CONTROLLING PESTS BASED ON SUBSTITUTED OXAZOLIDINONE, NEW SUBSTITUTED OXAZOLIDINONE, THEIR PRODUCTION AND USE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853408A (en) * 1985-04-23 1989-08-01 Roussel Uclaf 4-phenylpropyl-indoles having antiarythmic activity
FR2583047B1 (en) * 1985-06-05 1988-01-08 Roussel Uclaf PROCESS FOR THE PREPARATION OF INDOLE 4-PHENYLPROPYL DERIVATIVES AND INTERMEDIATES
FR2584713B1 (en) * 1985-07-11 1988-09-09 Roussel Uclaf NOVEL CARBOXAMIDE INDOLE DERIVATIVES, SALTS THEREOF, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
EP0275762B1 (en) * 1986-12-19 1993-11-18 Roussel-Uclaf Indole carboxamide derivatives and their salts, process and intermediates for their preparation, their use as medicines and compositions containing them

Also Published As

Publication number Publication date
FI880064A0 (en) 1988-01-08
FI85140B (en) 1991-11-29
ATE62673T1 (en) 1991-05-15
EP0275221A2 (en) 1988-07-20
JPS63188664A (en) 1988-08-04
DE3862380D1 (en) 1991-05-23
HUT45491A (en) 1988-07-28
FI880064A (en) 1988-07-10
EP0275221A3 (en) 1988-08-24
IE880039L (en) 1988-07-09
DK3288A (en) 1988-07-10
EP0275221B1 (en) 1991-04-17
GR3002185T3 (en) 1992-12-30
ES2029033T3 (en) 1992-07-16
AU619728B2 (en) 1992-02-06
DK168377B1 (en) 1994-03-21
DK3288D0 (en) 1988-01-06
FI85140C (en) 1992-03-10
IE60779B1 (en) 1994-08-10
FR2609464A1 (en) 1988-07-15
HU201910B (en) 1991-01-28
FR2609464B1 (en) 1990-12-07
AU1012988A (en) 1988-07-14
KR880008988A (en) 1988-09-13

Similar Documents

Publication Publication Date Title
SE7900987L (en) ALKYLENDIAMINE DERIVATIVES
ES8503476A1 (en) Acrylic-acid amides, their preparation and use.
IE850140L (en) Methylenediphosphonic acid derivatives antirheumatic agents
ES8103030A1 (en) Benzamide derivatives and herbicidal composition containing the same
GB1154260A (en) N-Aromatically Substituted Acid Amides
ES8103007A1 (en) Derivatives of 2-hydroxy-naphthalene and diazo photographic material containing them as coupling components.
AU579116B2 (en) Use of quinoline derivatives for the protection of cultivated plants
ZA8837B (en) N-(1h-indol-4-yl)benzamide derivatives and also their salts,their application by way of medicinal products and the compositions containing them
ES8204414A1 (en) Amides of p-isobutyl-phenyl-propionic acid
GB1109308A (en) Heterocyclic alkanoic acid amides
ES463557A2 (en) N-(4-piperidyl)-benzamides and pharmaceutical compositions containing them
SE436870B (en) SET TO MAKE NEW N-SUBSTITUTED Cinnamic Acid Amides
ES8404150A1 (en) N-pteridinyl ureas, process for their preparation and their use.
AU4475993A (en) Carbamic acid derivatives
IL72681A (en) 4-alkyl-5-haloimidazole-1-carboxylic acid esters and amides,their preparation and their use as nitrification inhibitors
DE3468868D1 (en) Iminosulfon amides and processes for their preparation, pharmaceutical preparations containing such compounds, and the compounds for use
ES334530A1 (en) N-substituted amides of -acylamino-acrylic acids
NZ223664A (en) 2,3-dihydro-3-phenyl-2-oxo-benzofuranylacetic acid amide derivatives and pharmaceutical compositions
ES8606245A1 (en) Herbicidal Substituted Phenoxyanilines and Pyridyloxyanilines
ES8601122A1 (en) 2-Thiocyanato benzamides.
ES8407042A1 (en) Sulpiride derived compound
GB799778A (en) New n-alkyl-alkyl-piperidine-monocarboxylic acid amides and n-alkyl-alkyl-pyrrolidine-monocarboxylic acid amides
ES8202336A1 (en) Aminothiazoline derivatives
ES451645A1 (en) 3-( alpha -Cyanoalkyl)carbamyl benzimidazolyl carbamates
GB920755A (en) Basically substituted phenyl-thiocarbamic acid-s-esters