GB920755A - Basically substituted phenyl-thiocarbamic acid-s-esters - Google Patents
Basically substituted phenyl-thiocarbamic acid-s-estersInfo
- Publication number
- GB920755A GB920755A GB1268961A GB1268961A GB920755A GB 920755 A GB920755 A GB 920755A GB 1268961 A GB1268961 A GB 1268961A GB 1268961 A GB1268961 A GB 1268961A GB 920755 A GB920755 A GB 920755A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- halogen atom
- alkyl
- nr1r2
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The invention comprises compounds of the general formula <FORM:0920755/IV(a)/1> (wherein X and Y, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl, alkoxy, nitro or cyano radical, A represents a straight or branched alkylene radical, and R1 and R2 represent alkyl or cycloalkyl radicals or jointly form with N a heterocyclic ring containing a second nitrogen atom which carries a hydrogen atom or a C1-4 alkyl radical) and their acid addition salts and quaternary ammonium compounds, and the preparation thereof by reacting an isocyanate of the general formula <FORM:0920755/IV(a)/2> with a thioalcohol of the general formula HS-A-Z (wherein Z represents -NR1R2 or a halogen atom or a hydroxy, optionally protected amino, nitrile or carbonamide group), or an amine of the general formula <FORM:0920755/IV(a)/3> with a haloformic ester of the general formula Hal-CO-S-A-Z (wherein Hal represents a halogen atom), or a salt of a thiocarbamic acid of the general formula <FORM:0920755/IV(a)/4> with a reactive ester of an alcohol of the general formula HO-A-Z, and in all cases subsequently converting Z into -NR1R2 if it is not this already, and, if desired, converting the product into an acid addition salt or quaternary ammonium compound. The products have inflammation-inhibiting properties.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF30948A DE1149709B (en) | 1960-04-07 | 1960-04-07 | Process for the preparation of basic substituted phenylthiocarbamic acid S-alkyl esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB920755A true GB920755A (en) | 1963-03-13 |
Family
ID=7093990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1268961A Expired GB920755A (en) | 1960-04-07 | 1961-04-07 | Basically substituted phenyl-thiocarbamic acid-s-esters |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE602274A (en) |
| DE (1) | DE1149709B (en) |
| GB (1) | GB920755A (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB599178A (en) * | 1945-10-03 | 1948-03-05 | John Woolley Batty | Thiolcarbamic esters |
| GB599179A (en) * | 1945-10-03 | 1948-03-05 | John Woolley Batty | Thiolcarbamic esters |
| DE896490C (en) * | 1950-11-01 | 1953-11-12 | Wingfoot Corp | Process for the preparation of organic isocyanates containing a thiourethane group |
-
1960
- 1960-04-07 DE DEF30948A patent/DE1149709B/en active Pending
-
1961
- 1961-04-06 BE BE602274A patent/BE602274A/en unknown
- 1961-04-07 GB GB1268961A patent/GB920755A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1149709B (en) | 1963-06-06 |
| BE602274A (en) | 1961-07-31 |
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