GB1021946A - Alkyleniminopropionic compounds and the preparation thereof - Google Patents
Alkyleniminopropionic compounds and the preparation thereofInfo
- Publication number
- GB1021946A GB1021946A GB14822/64A GB1482264A GB1021946A GB 1021946 A GB1021946 A GB 1021946A GB 14822/64 A GB14822/64 A GB 14822/64A GB 1482264 A GB1482264 A GB 1482264A GB 1021946 A GB1021946 A GB 1021946A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- preparation
- compounds
- bis
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
Abstract
The invention comprises compounds of the general formula <FORM:1021946/C2/1> wherein R1 and R2 are hydrogen or C1-C4 alkyl and R3 or R4 are hydrogen, and the preparation thereof by reacting a compound of the general formula <FORM:1021946/C2/2> with N,N1-bis-acryloylpiperazine, preferably in the presence of a tertiary amine in the temperature range - 10 DEG to 100 DEG C., preferably in the presence of a solvent and with the reactants ordinarily in the required molecular ratio of 2 : 1. N,N1 - bis - acryloyl - piperazine may be prepared by condensing piperazine with acryloyl chloride. A carcinostatic composition comprises a compound of the above general formula and an inert carrier, e.g. ethylene glycol for injectable solutions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1915363 | 1963-04-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1021946A true GB1021946A (en) | 1966-03-09 |
Family
ID=11991466
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB14822/64A Expired GB1021946A (en) | 1963-04-11 | 1964-04-09 | Alkyleniminopropionic compounds and the preparation thereof |
Country Status (6)
Country | Link |
---|---|
US (1) | US3196156A (en) |
BE (1) | BE646325A (en) |
CH (1) | CH454870A (en) |
DE (1) | DE1216313B (en) |
FR (1) | FR1561905A (en) |
GB (1) | GB1021946A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3511840A (en) * | 1963-08-13 | 1970-05-12 | Stevens & Co Inc J P | Polyfunctional piperazine amides |
US3520889A (en) * | 1965-06-01 | 1970-07-21 | Stevens & Co Inc J P | Sulfonamide aziridinyl compounds |
LU81694A1 (en) * | 1979-09-17 | 1981-04-17 | Oreal | COMPOSITION CONTAINING QUATERNARY AMMONIUM BIS DERIVATIVES WITH TWO LIPOPHILIC CHAINS FOR THE TREATMENT OF KERATINIC MATERIALS AND NOVEL COMPOUNDS USED |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA673586A (en) * | 1963-11-05 | W. Horrom Bruce | Substituted piperazines |
-
1964
- 1964-04-03 US US357296A patent/US3196156A/en not_active Expired - Lifetime
- 1964-04-06 CH CH429664A patent/CH454870A/en unknown
- 1964-04-09 BE BE646325D patent/BE646325A/xx unknown
- 1964-04-09 FR FR1561905D patent/FR1561905A/fr not_active Expired
- 1964-04-09 GB GB14822/64A patent/GB1021946A/en not_active Expired
- 1964-04-10 DE DES90480A patent/DE1216313B/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US3196156A (en) | 1965-07-20 |
DE1216313B (en) | 1966-05-12 |
BE646325A (en) | 1964-07-31 |
FR1561905A (en) | 1969-04-04 |
CH454870A (en) | 1968-04-30 |
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