GB1021946A - Alkyleniminopropionic compounds and the preparation thereof - Google Patents

Alkyleniminopropionic compounds and the preparation thereof

Info

Publication number
GB1021946A
GB1021946A GB14822/64A GB1482264A GB1021946A GB 1021946 A GB1021946 A GB 1021946A GB 14822/64 A GB14822/64 A GB 14822/64A GB 1482264 A GB1482264 A GB 1482264A GB 1021946 A GB1021946 A GB 1021946A
Authority
GB
United Kingdom
Prior art keywords
general formula
preparation
compounds
bis
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB14822/64A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of GB1021946A publication Critical patent/GB1021946A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom

Abstract

The invention comprises compounds of the general formula <FORM:1021946/C2/1> wherein R1 and R2 are hydrogen or C1-C4 alkyl and R3 or R4 are hydrogen, and the preparation thereof by reacting a compound of the general formula <FORM:1021946/C2/2> with N,N1-bis-acryloylpiperazine, preferably in the presence of a tertiary amine in the temperature range - 10 DEG to 100 DEG C., preferably in the presence of a solvent and with the reactants ordinarily in the required molecular ratio of 2 : 1. N,N1 - bis - acryloyl - piperazine may be prepared by condensing piperazine with acryloyl chloride. A carcinostatic composition comprises a compound of the above general formula and an inert carrier, e.g. ethylene glycol for injectable solutions.
GB14822/64A 1963-04-11 1964-04-09 Alkyleniminopropionic compounds and the preparation thereof Expired GB1021946A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1915363 1963-04-11

Publications (1)

Publication Number Publication Date
GB1021946A true GB1021946A (en) 1966-03-09

Family

ID=11991466

Family Applications (1)

Application Number Title Priority Date Filing Date
GB14822/64A Expired GB1021946A (en) 1963-04-11 1964-04-09 Alkyleniminopropionic compounds and the preparation thereof

Country Status (6)

Country Link
US (1) US3196156A (en)
BE (1) BE646325A (en)
CH (1) CH454870A (en)
DE (1) DE1216313B (en)
FR (1) FR1561905A (en)
GB (1) GB1021946A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511840A (en) * 1963-08-13 1970-05-12 Stevens & Co Inc J P Polyfunctional piperazine amides
US3520889A (en) * 1965-06-01 1970-07-21 Stevens & Co Inc J P Sulfonamide aziridinyl compounds
LU81694A1 (en) * 1979-09-17 1981-04-17 Oreal COMPOSITION CONTAINING QUATERNARY AMMONIUM BIS DERIVATIVES WITH TWO LIPOPHILIC CHAINS FOR THE TREATMENT OF KERATINIC MATERIALS AND NOVEL COMPOUNDS USED

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA673586A (en) * 1963-11-05 W. Horrom Bruce Substituted piperazines

Also Published As

Publication number Publication date
US3196156A (en) 1965-07-20
DE1216313B (en) 1966-05-12
BE646325A (en) 1964-07-31
FR1561905A (en) 1969-04-04
CH454870A (en) 1968-04-30

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