ES422931A1 - Pharmaceutical compositions containing dioxo-isoquinoline derivatives - Google Patents
Pharmaceutical compositions containing dioxo-isoquinoline derivativesInfo
- Publication number
- ES422931A1 ES422931A1 ES422931A ES422931A ES422931A1 ES 422931 A1 ES422931 A1 ES 422931A1 ES 422931 A ES422931 A ES 422931A ES 422931 A ES422931 A ES 422931A ES 422931 A1 ES422931 A1 ES 422931A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- isoquinoline derivatives
- dioxo
- containing dioxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/14—Monocyclic dicarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Process for the preparation of novel acid amides of the formula I < IMAGE > in which R1 to R3 which are identical or different, denote hydrogen or alkyl having 1 to 3 carbon atoms. The novel compounds are distinguished by useful pharmacological properties, in particular by muscle-relaxant, sedating, antiarrhythmic and anticonvulsive actions. They are prepared, starting from the corresponding isochromanones or the corresponding dicarboxylic acids, by reaction with suitably substituted glycinamides or their acid addition salts.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2237770A DE2237770A1 (en) | 1972-08-01 | 1972-08-01 | NEW ACID AMID |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422931A1 true ES422931A1 (en) | 1976-06-16 |
Family
ID=5852334
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417443A Expired ES417443A1 (en) | 1972-08-01 | 1973-07-31 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422931A Expired ES422931A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422933A Expired ES422933A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422932A Expired ES422932A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422930A Expired ES422930A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422929A Expired ES422929A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417443A Expired ES417443A1 (en) | 1972-08-01 | 1973-07-31 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422933A Expired ES422933A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422932A Expired ES422932A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422930A Expired ES422930A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
| ES422929A Expired ES422929A1 (en) | 1972-08-01 | 1974-02-05 | Pharmaceutical compositions containing dioxo-isoquinoline derivatives |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS558973B2 (en) |
| AT (2) | AT329059B (en) |
| AU (1) | AU476552B2 (en) |
| BE (1) | BE803086A (en) |
| CH (6) | CH615918A5 (en) |
| DE (1) | DE2237770A1 (en) |
| DK (1) | DK137008C (en) |
| ES (6) | ES417443A1 (en) |
| FI (1) | FI52218C (en) |
| FR (1) | FR2194435A1 (en) |
| GB (1) | GB1450793A (en) |
| NL (1) | NL7310562A (en) |
-
1972
- 1972-08-01 DE DE2237770A patent/DE2237770A1/en active Pending
-
1973
- 1973-07-30 FR FR7327882A patent/FR2194435A1/fr not_active Withdrawn
- 1973-07-30 CH CH1106573A patent/CH615918A5/en not_active IP Right Cessation
- 1973-07-31 GB GB3638873A patent/GB1450793A/en not_active Expired
- 1973-07-31 BE BE134124A patent/BE803086A/en unknown
- 1973-07-31 JP JP8629773A patent/JPS558973B2/ja not_active Expired
- 1973-07-31 ES ES417443A patent/ES417443A1/en not_active Expired
- 1973-07-31 FI FI732412A patent/FI52218C/en active
- 1973-07-31 DK DK420373A patent/DK137008C/en active
- 1973-07-31 NL NL7310562A patent/NL7310562A/xx not_active Application Discontinuation
- 1973-07-31 AU AU58735/73A patent/AU476552B2/en not_active Expired
- 1973-08-01 AT AT673773A patent/AT329059B/en not_active IP Right Cessation
- 1973-09-01 AT AT225975*7A patent/AT329060B/en not_active IP Right Cessation
-
1974
- 1974-02-05 ES ES422931A patent/ES422931A1/en not_active Expired
- 1974-02-05 ES ES422933A patent/ES422933A1/en not_active Expired
- 1974-02-05 ES ES422932A patent/ES422932A1/en not_active Expired
- 1974-02-05 ES ES422930A patent/ES422930A1/en not_active Expired
- 1974-02-05 ES ES422929A patent/ES422929A1/en not_active Expired
-
1978
- 1978-05-07 CH CH498578A patent/CH611887A5/en not_active IP Right Cessation
- 1978-05-08 CH CH498678A patent/CH615423A5/en not_active IP Right Cessation
- 1978-06-12 CH CH638978A patent/CH611888A5/en not_active IP Right Cessation
- 1978-06-12 CH CH638878A patent/CH612184A5/en not_active IP Right Cessation
- 1978-06-12 CH CH639078A patent/CH611280A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI52218B (en) | 1977-03-31 |
| FR2194435A1 (en) | 1974-03-01 |
| ATA673773A (en) | 1975-07-15 |
| ES422933A1 (en) | 1976-06-16 |
| JPS4980080A (en) | 1974-08-02 |
| ES417443A1 (en) | 1976-03-16 |
| AU476552B2 (en) | 1976-09-30 |
| CH611888A5 (en) | 1979-06-29 |
| BE803086A (en) | 1974-01-31 |
| ES422932A1 (en) | 1976-06-16 |
| ATA225975A (en) | 1975-07-15 |
| CH611280A5 (en) | 1979-05-31 |
| CH611887A5 (en) | 1979-06-29 |
| AT329059B (en) | 1976-04-26 |
| AU5873573A (en) | 1975-02-06 |
| NL7310562A (en) | 1974-02-05 |
| ES422929A1 (en) | 1976-06-16 |
| CH612184A5 (en) | 1979-07-13 |
| DK137008B (en) | 1978-01-02 |
| AT329060B (en) | 1976-04-26 |
| ES422930A1 (en) | 1976-06-16 |
| DE2237770A1 (en) | 1974-02-14 |
| GB1450793A (en) | 1976-09-29 |
| FI52218C (en) | 1977-07-11 |
| CH615918A5 (en) | 1980-02-29 |
| JPS558973B2 (en) | 1980-03-07 |
| DK137008C (en) | 1978-05-22 |
| CH615423A5 (en) | 1980-01-31 |
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