IE38234B1 - Tricyclic tetrazole derivatives their synthesis and composistions containing them - Google Patents

Tricyclic tetrazole derivatives their synthesis and composistions containing them

Info

Publication number
IE38234B1
IE38234B1 IE1589/73A IE158973A IE38234B1 IE 38234 B1 IE38234 B1 IE 38234B1 IE 1589/73 A IE1589/73 A IE 1589/73A IE 158973 A IE158973 A IE 158973A IE 38234 B1 IE38234 B1 IE 38234B1
Authority
IE
Ireland
Prior art keywords
compounds
radicals
formula
meaning stated
composistions
Prior art date
Application number
IE1589/73A
Other versions
IE38234L (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE38234L publication Critical patent/IE38234L/en
Publication of IE38234B1 publication Critical patent/IE38234B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86—Oxygen atoms, e.g. xanthones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Polycyclic compounds which contain at least one tetrazole ring and have the formula 1 in which the radicals Z<1>, Z<2> and Z<3> have the meaning stated in Claim 1 are obtained by reacting compounds of the formula 2 in which the radicals Y<1> and Y<2> have the meaning stated in Claim 1 with hydrazoic acid or a salt thereof, or by reacting compounds of the formula 2 in which the radicals Y<1> and Y<2> have the meaning stated in Claim 10 with nitrous acid, or by reacting compounds of the formula 2 in which the radicals Y<1> and Y<2> have the meaning stated in Claim 19 with nitrous acid and reducing the nitrosation product which is formed. The compounds are converted where appropriate into their salts or, if at least one of the substituents Z<1> and Z<2> is a carboxyl group, into their esters or amides by esterification or amidation. The compounds act as inhibitors in certain allergic reactions in mammals. <IMAGE> [GB1452891A]
IE1589/73A 1972-09-06 1973-09-06 Tricyclic tetrazole derivatives their synthesis and composistions containing them IE38234B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB4143072 1972-09-06
GB4143272 1972-09-06
GB4143172 1972-09-06
GB820073*[A GB1452891A (en) 1972-09-06 1973-02-20 Tricyclic tetrazole derivatives their synthesis and compositions containing them
GB829273 1973-02-20

Publications (2)

Publication Number Publication Date
IE38234L IE38234L (en) 1974-03-06
IE38234B1 true IE38234B1 (en) 1978-02-01

Family

ID=27515847

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1589/73A IE38234B1 (en) 1972-09-06 1973-09-06 Tricyclic tetrazole derivatives their synthesis and composistions containing them

Country Status (8)

Country Link
JP (1) JPS5849549B2 (en)
CH (1) CH626613A5 (en)
DE (1) DE2344814A1 (en)
FR (1) FR2197606B1 (en)
GB (1) GB1452891A (en)
IE (1) IE38234B1 (en)
IL (1) IL43160A (en)
NL (1) NL7312282A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4598155A (en) * 1981-11-18 1986-07-01 Ciba-Geigy Corporation 3(5-tetrazolyl)1,4-diaminoanthraquinones
US4714669A (en) * 1985-04-11 1987-12-22 Ciba-Geigy Corporation Radiation-sensitive polycondensates, their preparation, material coated therewith and the use thereof
US20040248926A1 (en) * 2001-11-13 2004-12-09 Hayashi Ken-Ichi Preventive or remedy for pruritus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759292A (en) * 1969-11-27 1971-05-24 Allen & Hanburys Ltd XANTHONE DERIVATIVES, THEIR PREPARATION AND THEIR USE
GB1339010A (en) * 1970-11-27 1973-11-28 Allen & Hanburys Ltd Tetrazolyl-anthraquinone derivatives

Also Published As

Publication number Publication date
IL43160A0 (en) 1973-11-28
NL7312282A (en) 1974-03-08
GB1452891A (en) 1976-10-20
IE38234L (en) 1974-03-06
IL43160A (en) 1977-02-28
CH626613A5 (en) 1981-11-30
JPS4985069A (en) 1974-08-15
JPS5849549B2 (en) 1983-11-05
FR2197606A1 (en) 1974-03-29
FR2197606B1 (en) 1976-05-14
DE2344814A1 (en) 1974-03-14
AU6003873A (en) 1975-03-06

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