ES420221A1 - Pharmaceutical compositions containing styrylpyridine derivatives - Google Patents

Pharmaceutical compositions containing styrylpyridine derivatives

Info

Publication number
ES420221A1
ES420221A1 ES420221A ES420221A ES420221A1 ES 420221 A1 ES420221 A1 ES 420221A1 ES 420221 A ES420221 A ES 420221A ES 420221 A ES420221 A ES 420221A ES 420221 A1 ES420221 A1 ES 420221A1
Authority
ES
Spain
Prior art keywords
group
formula
iiia
iia
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES420221A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robapharm AG
Original Assignee
Robapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robapharm AG filed Critical Robapharm AG
Publication of ES420221A1 publication Critical patent/ES420221A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A process for the preparation of stylbazole-derived compounds of the formula (I) or (II) or a respective acid addition salt: ** (See formula) ** in whose formulas "Py" represents a substituted or unsubstituted, N-oxidized or quatemized 2-, 3- or 4-pyridyl group, R1 represents a carboxylic acid group, a group that is converted in the human body to a carboxylic acid group or an acyl group, R2, R3 and R4 each represent hydrogen, a carboxylic acid group, a group that converts in the human body to a carboxylic acid group, an acyl group, a hydroxy group, an alkoxy group, an aralkoxy group or an aryloxy group, an esterified hydroxy group or a nitro, halogen or amino group, whose method comprises reacting a compound of formula (IA), (IA'), (IIA) or (IIA') with a compound (III) and/or alternatively reacting a compound of formula (IB) or (IIB) with a compound of the formula (IIIA) or (IIIA'): ** (See formula) ** in which formulas IA, IA', IIA, IIA', IB, IIB, III, IIIA and IIIA', the symbols R1, R2, R3, R4 and Py have the indicated meaning in relation to formulas (I) and (II) and Ra, Rb and Rc are the same or different and each is lower alkyl, aralkyl or aryl. (Machine-translation by Google Translate, not legally binding)
ES420221A 1972-11-04 1973-11-03 Pharmaceutical compositions containing styrylpyridine derivatives Expired ES420221A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5092472A GB1448366A (en) 1972-11-04 1972-11-04 Pharmaceutical compositions containing styrylpyridine derivatives

Publications (1)

Publication Number Publication Date
ES420221A1 true ES420221A1 (en) 1976-03-16

Family

ID=10457952

Family Applications (1)

Application Number Title Priority Date Filing Date
ES420221A Expired ES420221A1 (en) 1972-11-04 1973-11-03 Pharmaceutical compositions containing styrylpyridine derivatives

Country Status (13)

Country Link
JP (1) JPS49132078A (en)
AU (1) AU6218673A (en)
BE (1) BE806871A (en)
BG (1) BG20558A3 (en)
DD (1) DD107919A5 (en)
DE (1) DE2355195A1 (en)
ES (1) ES420221A1 (en)
FR (1) FR2205329B1 (en)
GB (1) GB1448366A (en)
HU (1) HU167662B (en)
IL (1) IL43550A0 (en)
NL (1) NL7315093A (en)
ZA (1) ZA738505B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1134828A (en) 1978-12-28 1982-11-02 Tadao Tanouchi Pyridine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3580909A (en) * 1968-12-09 1971-05-25 Hoffmann La Roche 4-styrylpyridines

Also Published As

Publication number Publication date
NL7315093A (en) 1974-05-07
BE806871A (en) 1974-04-30
AU6218673A (en) 1975-05-08
ZA738505B (en) 1974-09-25
FR2205329A1 (en) 1974-05-31
DE2355195A1 (en) 1974-05-16
HU167662B (en) 1975-11-28
GB1448366A (en) 1976-09-08
IL43550A0 (en) 1974-03-14
BG20558A3 (en) 1975-12-05
FR2205329B1 (en) 1976-07-02
JPS49132078A (en) 1974-12-18
DD107919A5 (en) 1974-08-20

Similar Documents

Publication Publication Date Title
GB1437781A (en) Pyridine derivatives having hypoglycaemic activity
ES462065A1 (en) Thiazolidine derivatives
ES394370A1 (en) Pharmacologically active 3-piperazinyl-carbonyloxy-2-pyridyl-isoindolin-1-ones
ES421067A1 (en) Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding)
ES420221A1 (en) Pharmaceutical compositions containing styrylpyridine derivatives
ES417471A1 (en) Acylated n6-aralkyl-adenosine derivatives
ES407866A1 (en) Preparation of n -diethylaminoethyl - 2 - methoxy- 5 - methyl sulphonylbenzamide
ES405645A1 (en) Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding)
ES386847A1 (en) Amino-oxy carboxylic acid amides
ES401342A1 (en) Pyridine derivatives
GB1421580A (en) Production of benzylamine derivatives
ES445343A1 (en) Quaternary xanthinylalkyl nortropine
ES429691A1 (en) Preparation of p-isobutyl hydratropic acid and intermediates therefor
ES429817A1 (en) 6-trichloroacetamido-penicillanic acid derivatives and their preparation
ES382438A1 (en) Pharmaceutical compositions
GB1032377A (en) Asymmetrical pyridoxolyl disulphides and their preparation
ES446295A1 (en) Derivatives of salicylic acid suitable for use in therapeutics
ES300123A1 (en) A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding)
ES446131A1 (en) A procedure for the preparation of new derivatives of 2-alkyl (bottom) -2 or 3-cefem-4-carboxylic acid. (Machine-translation by Google Translate, not legally binding)
ES410009A1 (en) Process for preparing 7-acylamino-3-substituted-3-cephem-4- carboxylic acid derivatives
ES377995A1 (en) Procedure for the preparation of new derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding)
ES379120A1 (en) Procedure for the preparation of new derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding)
ES397562A1 (en) Sa 8-amino-theohylline derivatives process for their preparation and therapeutic compositon containing same
ES454153A2 (en) Triazole derivatives and processes for their production
ES429857A1 (en) 7-monochloroacetamido-3-desacetoxy-cephalosporanic acid derivatives their preparation and use