ES429691A1 - Preparation of p-isobutyl hydratropic acid and intermediates therefor - Google Patents

Preparation of p-isobutyl hydratropic acid and intermediates therefor

Info

Publication number
ES429691A1
ES429691A1 ES429691A ES429691A ES429691A1 ES 429691 A1 ES429691 A1 ES 429691A1 ES 429691 A ES429691 A ES 429691A ES 429691 A ES429691 A ES 429691A ES 429691 A1 ES429691 A1 ES 429691A1
Authority
ES
Spain
Prior art keywords
preparation
isobutyl
intermediates therefor
hydratropic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES429691A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Publication of ES429691A1 publication Critical patent/ES429691A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Abstract

Process for the preparation of p.isobutylhydratropic acid, characterized in that a compound of formula (II) is treated: **(See formula)** where alch represents a lower alkyl (1 to 5 carbon atoms) and the two alkyls may also be different from each other, as a mixture of two pairs of diesteromers, with strong acids in aqueous solution at a temperature between 200 and 240º, or, when presented in a bag, with strong acid salts with an organic base, for periods of time that vary between half an hour and 3 hours. (Machine-translation by Google Translate, not legally binding)
ES429691A 1974-04-11 1974-08-30 Preparation of p-isobutyl hydratropic acid and intermediates therefor Expired ES429691A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT5031574 1974-04-11

Publications (1)

Publication Number Publication Date
ES429691A1 true ES429691A1 (en) 1976-10-01

Family

ID=11272714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES429691A Expired ES429691A1 (en) 1974-04-11 1974-08-30 Preparation of p-isobutyl hydratropic acid and intermediates therefor

Country Status (11)

Country Link
JP (2) JPS553336B2 (en)
AR (1) AR201607A1 (en)
AT (1) AT338251B (en)
BE (1) BE820267A (en)
CA (1) CA1048054A (en)
DE (1) DE2452459A1 (en)
ES (1) ES429691A1 (en)
FI (1) FI340974A (en)
FR (1) FR2267303B1 (en)
GB (1) GB1462407A (en)
NL (1) NL7414715A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022440A1 (en) * 1979-06-22 1981-01-21 The Upjohn Company Process for preparing Michael addition products and for converting them to ibuprofen, an anti-inflammatory compound
JPS58147081U (en) * 1982-03-27 1983-10-03 サンデン株式会社 Coffee vending machine raw material information department
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1265800A (en) * 1917-04-07 1918-05-14 Ralph Harper Mckee Process of producing 1:2:4 methyl-hydroxy-isopropyl benzene.
GB1265800A (en) * 1968-11-05 1972-03-08

Also Published As

Publication number Publication date
FI340974A (en) 1975-10-12
GB1462407A (en) 1977-01-26
BE820267A (en) 1975-01-16
JPS50135026A (en) 1975-10-25
AT338251B (en) 1977-08-10
CA1048054A (en) 1979-02-06
FR2267303A1 (en) 1975-11-07
ATA858674A (en) 1976-12-15
FR2267303B1 (en) 1978-03-31
AR201607A1 (en) 1975-03-31
JPS5614654B2 (en) 1981-04-06
JPS50135049A (en) 1975-10-25
DE2452459A1 (en) 1975-10-23
JPS553336B2 (en) 1980-01-24
NL7414715A (en) 1975-10-14

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