ES412886A1 - A procedure for the preparation of tiazolcarboxilic acid derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of tiazolcarboxilic acid derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES412886A1 ES412886A1 ES412886A ES412886A ES412886A1 ES 412886 A1 ES412886 A1 ES 412886A1 ES 412886 A ES412886 A ES 412886A ES 412886 A ES412886 A ES 412886A ES 412886 A1 ES412886 A1 ES 412886A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- radical
- translation
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
A process for the preparation of derivatives of thiazolcarboxylic acids of general formula I: **(See formula)** where R1 represents an alcohol radical having 1 to 6 carbon atoms or a phenyl radical, R2 represents a hydrogen atom or an alcohol radical having 1 to 4 carbon atoms, X1 and X2 represent a hydrogen atom or of halogen, an alcoholic, alkoxyloxy or alcoholylthio radical having 1 to 4 carbon atoms, or a trifluoromethyl radical, and n represents an integer which may vary from 2 to 5, as well as of its addition salts with acids, characterized in that a thiazol-5-carboxylic acid of general formula II is reacted: **(See formula)** wherein R1 has the aforementioned meaning, or a functional derivative of this acid, with a phenylpiperazine of general formula III: **(See formula)** wherein R2, X1, X2 and n have the aforementioned meaning, and the amide obtained of general formula I is subjected, if desired, to the action of an acid to form the corresponding addition salt. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7210010A FR2176528B1 (en) | 1972-03-22 | 1972-03-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES412886A1 true ES412886A1 (en) | 1976-05-01 |
Family
ID=9095629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES412886A Expired ES412886A1 (en) | 1972-03-22 | 1973-03-21 | A procedure for the preparation of tiazolcarboxilic acid derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (5)
| Country | Link |
|---|---|
| ES (1) | ES412886A1 (en) |
| HU (1) | HU165121B (en) |
| IL (1) | IL41703A (en) |
| SU (1) | SU464115A3 (en) |
| ZA (1) | ZA731581B (en) |
-
1972
- 1972-03-07 ZA ZA731581A patent/ZA731581B/en unknown
-
1973
- 1973-03-06 IL IL41703A patent/IL41703A/en unknown
- 1973-03-21 SU SU1893650A patent/SU464115A3/en active
- 1973-03-21 ES ES412886A patent/ES412886A1/en not_active Expired
- 1973-03-21 HU HURO000713 patent/HU165121B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU464115A3 (en) | 1975-03-15 |
| IL41703A (en) | 1975-11-25 |
| ZA731581B (en) | 1974-04-24 |
| AU5358873A (en) | 1974-09-26 |
| IL41703A0 (en) | 1973-05-31 |
| HU165121B (en) | 1974-06-28 |
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