ES394894A1 - Phenylacetohydroxamic acids process for their manufacture and preparations containing them - Google Patents
Phenylacetohydroxamic acids process for their manufacture and preparations containing themInfo
- Publication number
- ES394894A1 ES394894A1 ES394894A ES394894A ES394894A1 ES 394894 A1 ES394894 A1 ES 394894A1 ES 394894 A ES394894 A ES 394894A ES 394894 A ES394894 A ES 394894A ES 394894 A1 ES394894 A1 ES 394894A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- hydrogen
- inclusive
- halogen
- atomic number
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for obtaining phenylacetohydroxamic acids of formula I ** (See formula) ** where R1 is hydrogen, lower alkyl, lower alkoxy or halogen with an atomic number of up to 35 inclusive, R2 is hydrogen, lower alkyl, lower alkoxy, halogen with an atomic number of up to 35 inclusive, or trifluomethyl, R3 is hydrogen, lower alkyl, lower alkoxy or halogen with atomic number up to 35 inclusive and R4 means hydrogen, lower alkyl, lower alkoxy or halogen with atomic number up to 35 inclusive, excluding the simultaneous definition of substituents R1, R2 and R3 as hydrogen, and its salts, characterized in that an amide or an acid ester of formula II ** (See formula) ** in which R1, R2, R3 and R4 have the meanings indicated for formula 1, it is reacted with hydroxylamine or a salt thereof in a basic medium and if desired, a compound obtained from formula I is transformed into a salt with an inorganic base. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1341570A CH550146A (en) | 1970-09-09 | 1970-09-09 | Substd anilino-phenyl acetylhydroxamic acids - anti-inflammatories , analgesics, antipyretics and uv absorbers in sun-screening |
| CH1058071 | 1971-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES394894A1 true ES394894A1 (en) | 1974-05-16 |
Family
ID=25706940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES394894A Expired ES394894A1 (en) | 1970-09-09 | 1971-09-08 | Phenylacetohydroxamic acids process for their manufacture and preparations containing them |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5544060B1 (en) |
| AT (1) | AT310720B (en) |
| BE (1) | BE772333A (en) |
| BR (1) | BR7105911D0 (en) |
| CS (1) | CS159288B2 (en) |
| DE (1) | DE2144641C3 (en) |
| DK (1) | DK143104C (en) |
| ES (1) | ES394894A1 (en) |
| FI (1) | FI55181C (en) |
| FR (1) | FR2106398B1 (en) |
| GB (1) | GB1331181A (en) |
| HU (1) | HU163847B (en) |
| IE (1) | IE35626B1 (en) |
| IL (1) | IL37678A (en) |
| NL (1) | NL175382C (en) |
| NO (1) | NO134946C (en) |
| SE (1) | SE379755B (en) |
| SU (1) | SU474975A3 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT72878B (en) * | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| US6355680B1 (en) * | 1996-02-20 | 2002-03-12 | Exocell, Inc. | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
| IT1283637B1 (en) * | 1996-05-14 | 1998-04-23 | Italfarmaco Spa | COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSOPPRESSIVE ACTIVITY |
| CN102976974B (en) * | 2012-12-29 | 2015-01-21 | 吉首大学 | Phenyl benzyl propionyl-N-methyloxyxamic urease inhibitor and synthesis and use thereof |
-
1971
- 1971-09-02 NO NO3282/71A patent/NO134946C/no unknown
- 1971-09-02 FI FI2453/71A patent/FI55181C/en active
- 1971-09-02 NL NLAANVRAGE7112085,A patent/NL175382C/en not_active IP Right Cessation
- 1971-09-02 DK DK431771A patent/DK143104C/en not_active IP Right Cessation
- 1971-09-02 SE SE7111125A patent/SE379755B/xx unknown
- 1971-09-07 DE DE2144641A patent/DE2144641C3/en not_active Expired
- 1971-09-08 FR FR7132401A patent/FR2106398B1/fr not_active Expired
- 1971-09-08 ES ES394894A patent/ES394894A1/en not_active Expired
- 1971-09-08 IL IL37678A patent/IL37678A/en unknown
- 1971-09-08 HU HUCI1157A patent/HU163847B/hu unknown
- 1971-09-08 BR BR5911/71A patent/BR7105911D0/en unknown
- 1971-09-08 JP JP6898671A patent/JPS5544060B1/ja active Pending
- 1971-09-08 GB GB4199071A patent/GB1331181A/en not_active Expired
- 1971-09-08 IE IE1144/71A patent/IE35626B1/en unknown
- 1971-09-08 BE BE772333A patent/BE772333A/en not_active IP Right Cessation
- 1971-09-08 CS CS640871A patent/CS159288B2/cs unknown
- 1971-09-08 AT AT780571A patent/AT310720B/en not_active IP Right Cessation
- 1971-09-09 SU SU1699014A patent/SU474975A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| DE2144641C3 (en) | 1980-12-04 |
| GB1331181A (en) | 1973-09-26 |
| SE379755B (en) | 1975-10-20 |
| IE35626B1 (en) | 1976-03-31 |
| BE772333A (en) | 1972-03-08 |
| FI55181B (en) | 1979-02-28 |
| NL7112085A (en) | 1972-03-13 |
| DE2144641B2 (en) | 1980-04-03 |
| SU474975A3 (en) | 1975-06-25 |
| IL37678A0 (en) | 1971-11-29 |
| NO134946B (en) | 1976-10-04 |
| NL175382C (en) | 1984-11-01 |
| CS159288B2 (en) | 1974-12-27 |
| BR7105911D0 (en) | 1973-05-10 |
| FI55181C (en) | 1979-06-11 |
| AT310720B (en) | 1973-10-10 |
| IL37678A (en) | 1974-10-22 |
| FR2106398A1 (en) | 1972-05-05 |
| FR2106398B1 (en) | 1974-10-18 |
| DK143104B (en) | 1981-03-30 |
| JPS5544060B1 (en) | 1980-11-10 |
| DK143104C (en) | 1981-11-09 |
| HU163847B (en) | 1973-11-28 |
| DE2144641A1 (en) | 1972-03-16 |
| NL175382B (en) | 1984-06-01 |
| IE35626L (en) | 1972-03-09 |
| NO134946C (en) | 1977-01-12 |
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