GB1331181A - Phenylacetohydroxamic acids process for their manufacture and preparations containing them - Google Patents
Phenylacetohydroxamic acids process for their manufacture and preparations containing themInfo
- Publication number
- GB1331181A GB1331181A GB4199071A GB4199071A GB1331181A GB 1331181 A GB1331181 A GB 1331181A GB 4199071 A GB4199071 A GB 4199071A GB 4199071 A GB4199071 A GB 4199071A GB 1331181 A GB1331181 A GB 1331181A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenylacetohydroxamic
- formula
- acids
- manufacture
- sept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1331181 Phenylacetohydroxamic acids CIBA-GEIGY AG 8 Sept 1971 [9 Sept 1970 16 July 1971] 41990/71 Heading C2C [Also in Division A5] Novel compounds of Formula I (in which each of R 1 , R 3 and R 4 is H, F, Cl, Br, C 1-6 alkyl or C 1-6 alkoxy and R 2 is H, F, Cl, Br, CF 3 , C 1-6 alkyl or C 1-6 alkoxy, with the proviso that at least one of R 1 , R 2 and R 3 is other than H) and salts thereof with inorganic bases, are prepared by reacting an amide or ester of an acid of Formula II with hydroxylamine or an acid addition salt thereof in a basic medium, and, if desired converting a resulting salt into the free acid or into another salt. Acids of Formula II and alkali metals salts, methyl, cyanomethyl and p-nitrophenyl esters and amides thereof are also disclosed.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1341570A CH550146A (en) | 1970-09-09 | 1970-09-09 | Substd anilino-phenyl acetylhydroxamic acids - anti-inflammatories , analgesics, antipyretics and uv absorbers in sun-screening |
| CH1058071 | 1971-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1331181A true GB1331181A (en) | 1973-09-26 |
Family
ID=25706940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4199071A Expired GB1331181A (en) | 1970-09-09 | 1971-09-08 | Phenylacetohydroxamic acids process for their manufacture and preparations containing them |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5544060B1 (en) |
| AT (1) | AT310720B (en) |
| BE (1) | BE772333A (en) |
| BR (1) | BR7105911D0 (en) |
| CS (1) | CS159288B2 (en) |
| DE (1) | DE2144641C3 (en) |
| DK (1) | DK143104C (en) |
| ES (1) | ES394894A1 (en) |
| FI (1) | FI55181C (en) |
| FR (1) | FR2106398B1 (en) |
| GB (1) | GB1331181A (en) |
| HU (1) | HU163847B (en) |
| IE (1) | IE35626B1 (en) |
| IL (1) | IL37678A (en) |
| NL (1) | NL175382C (en) |
| NO (1) | NO134946C (en) |
| SE (1) | SE379755B (en) |
| SU (1) | SU474975A3 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT72878B (en) * | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| US6355680B1 (en) * | 1996-02-20 | 2002-03-12 | Exocell, Inc. | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
| IT1283637B1 (en) * | 1996-05-14 | 1998-04-23 | Italfarmaco Spa | COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSOPPRESSIVE ACTIVITY |
| CN102976974B (en) * | 2012-12-29 | 2015-01-21 | 吉首大学 | Phenyl benzyl propionyl-N-methyloxyxamic urease inhibitor and synthesis and use thereof |
-
1971
- 1971-09-02 SE SE7111125A patent/SE379755B/xx unknown
- 1971-09-02 FI FI2453/71A patent/FI55181C/en active
- 1971-09-02 DK DK431771A patent/DK143104C/en not_active IP Right Cessation
- 1971-09-02 NO NO3282/71A patent/NO134946C/no unknown
- 1971-09-02 NL NLAANVRAGE7112085,A patent/NL175382C/en not_active IP Right Cessation
- 1971-09-07 DE DE2144641A patent/DE2144641C3/en not_active Expired
- 1971-09-08 HU HUCI1157A patent/HU163847B/hu unknown
- 1971-09-08 BE BE772333A patent/BE772333A/en not_active IP Right Cessation
- 1971-09-08 AT AT780571A patent/AT310720B/en not_active IP Right Cessation
- 1971-09-08 IE IE1144/71A patent/IE35626B1/en unknown
- 1971-09-08 CS CS640871A patent/CS159288B2/cs unknown
- 1971-09-08 FR FR7132401A patent/FR2106398B1/fr not_active Expired
- 1971-09-08 GB GB4199071A patent/GB1331181A/en not_active Expired
- 1971-09-08 ES ES394894A patent/ES394894A1/en not_active Expired
- 1971-09-08 BR BR5911/71A patent/BR7105911D0/en unknown
- 1971-09-08 JP JP6898671A patent/JPS5544060B1/ja active Pending
- 1971-09-08 IL IL37678A patent/IL37678A/en unknown
- 1971-09-09 SU SU1699014A patent/SU474975A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2106398A1 (en) | 1972-05-05 |
| DK143104C (en) | 1981-11-09 |
| DK143104B (en) | 1981-03-30 |
| FR2106398B1 (en) | 1974-10-18 |
| NL175382B (en) | 1984-06-01 |
| NO134946B (en) | 1976-10-04 |
| IL37678A0 (en) | 1971-11-29 |
| ES394894A1 (en) | 1974-05-16 |
| DE2144641A1 (en) | 1972-03-16 |
| IL37678A (en) | 1974-10-22 |
| FI55181B (en) | 1979-02-28 |
| FI55181C (en) | 1979-06-11 |
| BE772333A (en) | 1972-03-08 |
| NL175382C (en) | 1984-11-01 |
| DE2144641B2 (en) | 1980-04-03 |
| SE379755B (en) | 1975-10-20 |
| NL7112085A (en) | 1972-03-13 |
| NO134946C (en) | 1977-01-12 |
| AT310720B (en) | 1973-10-10 |
| DE2144641C3 (en) | 1980-12-04 |
| CS159288B2 (en) | 1974-12-27 |
| JPS5544060B1 (en) | 1980-11-10 |
| IE35626B1 (en) | 1976-03-31 |
| HU163847B (en) | 1973-11-28 |
| IE35626L (en) | 1972-03-09 |
| SU474975A3 (en) | 1975-06-25 |
| BR7105911D0 (en) | 1973-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |