GB1292662A - Bicycloheptaneheptanoic acids and esters thereof - Google Patents
Bicycloheptaneheptanoic acids and esters thereofInfo
- Publication number
- GB1292662A GB1292662A GB9562/72A GB956272A GB1292662A GB 1292662 A GB1292662 A GB 1292662A GB 9562/72 A GB9562/72 A GB 9562/72A GB 956272 A GB956272 A GB 956272A GB 1292662 A GB1292662 A GB 1292662A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- esters
- bicycloheptaneheptanoic
- acids
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- ARUKYTASOALXFG-UHFFFAOYSA-N cycloheptylcycloheptane Chemical class C1CCCCCC1C1CCCCCC1 ARUKYTASOALXFG-UHFFFAOYSA-N 0.000 abstract 2
- LBOKTHVXIPFAJO-UHFFFAOYSA-N 7-(5-oxocyclopenten-1-yl)heptanoic acid Chemical compound OC(=O)CCCCCCC1=CCCC1=O LBOKTHVXIPFAJO-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- UCUUFSAXZMGPGH-UHFFFAOYSA-N penta-1,4-dien-3-one Chemical class C=CC(=O)C=C UCUUFSAXZMGPGH-UHFFFAOYSA-N 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
1292662 Bicycloheptane derivatives AYERST McKENNA & HARRISON Ltd 22 Oct 1969 [22 Oct 1968 28 July 1969] 9562/72 Divided out of 1292661 Heading C2C Novel bicycloheptane derivatives of the Formula I in which R<SP>2</SP> is H or C 1-3 alkyl ; Y is H or Cl and n is 1 to 6 are prepared by reacting 2-(6- carboxyhexyl) - cyclopent - 2 - en - 1 - one or the C 1-3 alkyl esters thereof in the presence of ultra-violet light with vinyl ketones of the formula to give compounds of the above Formula I in which Y is Cl, and, if desired, reacting the compounds thus obtained with zinc and acetic acid to give compounds of the above Formula I in which Y is H.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76975068A | 1968-10-22 | 1968-10-22 | |
US84553269A | 1969-07-28 | 1969-07-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1292662A true GB1292662A (en) | 1972-10-11 |
Family
ID=27118218
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB51866/69A Expired GB1292661A (en) | 1968-10-22 | 1969-10-22 | Prostanoic acid derivatives and preparation thereof |
GB9562/72A Expired GB1292662A (en) | 1968-10-22 | 1969-10-22 | Bicycloheptaneheptanoic acids and esters thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB51866/69A Expired GB1292661A (en) | 1968-10-22 | 1969-10-22 | Prostanoic acid derivatives and preparation thereof |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS4843736B1 (en) |
DE (1) | DE1953232A1 (en) |
FR (1) | FR2021234B1 (en) |
GB (2) | GB1292661A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56171280U (en) * | 1980-05-21 | 1981-12-17 | ||
EP2329825B1 (en) * | 2005-03-04 | 2015-10-07 | Sucampo AG | Method and composition for treating peripheral vascular diseases |
-
1969
- 1969-10-21 FR FR6936080A patent/FR2021234B1/fr not_active Expired
- 1969-10-22 DE DE19691953232 patent/DE1953232A1/en active Pending
- 1969-10-22 JP JP44084577A patent/JPS4843736B1/ja active Pending
- 1969-10-22 GB GB51866/69A patent/GB1292661A/en not_active Expired
- 1969-10-22 GB GB9562/72A patent/GB1292662A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2021234A1 (en) | 1970-07-17 |
JPS4843736B1 (en) | 1973-12-20 |
FR2021234B1 (en) | 1974-11-15 |
DE1953232A1 (en) | 1970-04-30 |
GB1292661A (en) | 1972-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |