ES395958A1 - Hydroxyaryl amino acids - Google Patents

Hydroxyaryl amino acids

Info

Publication number
ES395958A1
ES395958A1 ES395958A ES395958A ES395958A1 ES 395958 A1 ES395958 A1 ES 395958A1 ES 395958 A ES395958 A ES 395958A ES 395958 A ES395958 A ES 395958A ES 395958 A1 ES395958 A1 ES 395958A1
Authority
ES
Spain
Prior art keywords
salt
acid
hydrogen atom
see formula
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES395958A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES395958A1 publication Critical patent/ES395958A1/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the production of an optionally substituted parahydroxyphenyl-α-amino acid (II) **(See formula)** or an acylic salt or derivatives thereof, where R1 is a hydrogen atom or a lower acyl group and R2, R3 and R4 are each a hydrogen or halogen atom or a hydroxyl, lower alkoxy, lower alkyl or acid group optionally esterified carboxylic acid or R3 and R4 attached to the carbon atoms to which they are attached form a carbocyclic ring, at least one of the radicals R2, R3 or R4 being a hydrogen atom; the procedure of which is to react one mole of glyoxylic acid or a precursor thereof with at least 1.3 mol of a compound of the general formula (V) or a salt thereof **(See formula)** and at least 1.5 moles of ammonia and then optionally forming a free acid, a salt or an N-acylated or O, N-diacylated derivative thereof, by known methods. (Machine-translation by Google Translate, not legally binding)
ES395958A 1970-10-15 1971-10-13 Hydroxyaryl amino acids Expired ES395958A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4894870 1970-10-15
GB1010571A GB1371896A (en) 1970-10-15 1971-04-20 Hydroxyaryl amino acids

Publications (1)

Publication Number Publication Date
ES395958A1 true ES395958A1 (en) 1977-02-01

Family

ID=26247279

Family Applications (1)

Application Number Title Priority Date Filing Date
ES395958A Expired ES395958A1 (en) 1970-10-15 1971-10-13 Hydroxyaryl amino acids

Country Status (8)

Country Link
BE (1) BE774029A (en)
CH (1) CH566965A5 (en)
DE (1) DE2151521A1 (en)
ES (1) ES395958A1 (en)
FR (1) FR2111362A5 (en)
GB (1) GB1371896A (en)
IT (1) IT944741B (en)
NL (1) NL7113621A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5917104B2 (en) * 1977-05-02 1984-04-19 田辺製薬株式会社 Method for producing hydroxyphenylglycine compounds
GB1576334A (en) * 1977-05-26 1980-10-08 Ici Ltd N-alkyl and n,n-dialkyl derivatives thereof process for the manufacture of p-hydroxyphenylglycine and
US5238958A (en) * 1990-02-26 1993-08-24 Warner-Lambert Company Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
NL9101380A (en) * 1991-08-13 1993-03-01 Dsm Nv PROCESS FOR THE PREPARATION OF AN ALFA-AMINOIC ACID, THE SIMILAR ESTER AND AMIDE.

Also Published As

Publication number Publication date
BE774029A (en) 1972-04-17
NL7113621A (en) 1972-04-18
IT944741B (en) 1973-04-20
GB1371896A (en) 1974-10-30
DE2151521A1 (en) 1972-04-20
CH566965A5 (en) 1975-09-30
FR2111362A5 (en) 1972-06-02

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